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Silvio Ragozzino

@docsilvio.bsky.social

Infectious disease physician - Médico Especialista en Medicina Interna - 'Napolide' - In un mondo di John e di Paul... #IDSky

727 Followers  |  99 Following  |  3 Posts  |  Joined: 15.11.2024  |  1.3055

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➡️ They may be rapid biomarkers and potential antifungal targets to differentiate C. albicans candidemia.
A further step toward molecular diagnosis in invasive fungal infections.
Thanks to the team for their great work 👏

07.12.2025 20:55 — 👍 0    🔁 0    💬 0    📌 0

🧪 20 patients with candidemia (10 C. albicans, 10 non-albicans) and 22 controls without sepsis.
📊 RNA-seq and qPCR revealed marked overexpression of miR-125a and miR-99b only in C. albicans.
🧬 These miRNAs were associated with repression of immune and cell-cycle genes.

07.12.2025 20:55 — 👍 1    🔁 0    💬 1    📌 0
Preview
MicroRNA whole-blood profiling in hospitalized patients with candidemia identified miR-125a-5p and miR-99b-5p as potential biomarkers for Candida albicans bloodstream infection Analyze miRNA and mRNA expression in patients with bloodstream infection (BSI) caused by Candida albicans (CA) and non-albicans Candida spp. (CNA).We …

I’m delighted to share this work from the research group led by
Dr. Miguel Marcos, derived from my doctoral thesis.
🔬 We studied miRNA and mRNA profiles in the blood of patients with candidemia caused by Candida albicans and other species. www.sciencedirect.com/science/arti...

07.12.2025 20:55 — 👍 1    🔁 0    💬 1    📌 0

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