Julien Roux

Thomas Hurd (Univ Toronto) @tomhurd on how paternal mtDNA gets “cut out of inheritance”; 100s of mtDNA in oocyte but <1 per sperm; this elimination takes place within spermatogenesis from immature to mature sperm; mtDNA eliminated but not mitochondria themselves (sperm need energy to swim) #Dros26

This year, ECCB comes to Geneva, Switzerland, hosted by SIB! Don’t miss your chance to join this exceptional event.
👇 Register now and be part of the leading European conference in computational biology:

New teaching video + paper out today on the role of gender in understanding sex disparities in adverse drug events!

This is the third of 3 videos we created to help build understanding and dialogue across fields and communities about the importance of considering gender-related variables.

Webinar at EMBL-EBI: Mapping tissue remodelling using sequencing-based spatial transcriptomics. 4 March 2026, 14:30-15:30 UK time. Speaker: Ricardo Ramirez, EMBL-EBI

Join us next week for the third free webinar in our spatial transcriptomics series: www.ebi.ac.uk/training/eve...

Ricardo Ramirez (EMBL-EBI) presents 'Mapping tissue remodelling using sequencing-based spatial transcriptomics' on 4 March| 14:30 UK time.

@saezlab.bsky.social
🧬🖥️

AI Keeps Failing at Microbiome Prediction Why simple models keep winning, where deep learning still shines, and where the field is headed

AI has huge promise for genomics -- but it has consistently failed at microbiome-based prediction.

My new post on why simple models keep winning, where deep learning actually earns its place, and where the field is headed

blekhman.substack.com/p/ai-keeps-f...

We have an opening in our team! See the link below if you are interested:

Universität Basel: Bioinformatician (100%) The Department of Biomedicine (DBM) is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health...

We have a 3-years position open in our facility. Come join us to do great science in a nice team!
jobs.unibas.ch/offene-stell...

Sex differences in health and disease

Sex differences in health and disease www.embl.org/about/info/c...

YouTube video by BiozentrumBasel Women in Science 2026

Happy International Day of Women & Girls in Science🧪. To mark this day, we feature three female scientists from our core facilities and share their professional journeys, which reflect the diversity of careers in science. #WIS #STEM
👉 www.biozentrum.unibas.ch/research/res...

youtu.be/BVkxirHBqJk

Again, if you were alive in the 1980s, this is among the most wonderful & truly incredible things you have ever witnessed in your lifetime.

Applications close for this 4-year postdoc on Feb 9th (2 days!). The associated post for a technician should be online next week 👀

Efficient near-telomere-to-telomere assembly of nanopore simplex reads - Nature A genome assembly method called hifiasm (ONT) allows the assembly of chromosomes from telomere to telomere without the need for ultra-long reads, and outperforms conventional methods on most evaluatio...

The most satisfying genome assembler to run, ever. Huge appreciation for the team behind hifiasm 👏

LOL. I can’t think of a better way to make sure they get loudly booed! Italian fans, please don’t disappoint

Actually, it's only 4 replicates per group (still not bad):
"Xenium spatial transcriptomics experiments were performed on aortas from db/db and db/dbDAPA groups (n=4/group)."

Unfortunately the GEO accessions are still private...

Cell type-specific responses to #Dapagliflozin in Diabetic arterial wall of db/db🐭

Take a look at this powerful multimodal single-cell dataset
scRNA-seq scATAC-seq Xenium (479 genes) #SpatialTranscriptomics
n=8🐭/group

Rama Natarajan lab #ATVB 2026
www.ahajournals.org/doi/10.1161/...

Gladys Mae West obituary: mathematician who pioneered GPS technology She made key contributions to US cold-war science despite facing huge barriers as a Black woman.

No joke: I got angry hate mail today for writing an obituary of a Black woman scientist—because the person felt she did didn’t deserve the recognition.

Which just makes me want to share it again: www.nature.com/articles/d41...

There must be a German word for it!

Interested in radical exploration in science? There's evidence that it can actually be the best strategy for discovery. We talk about it in our new episode of the Night Science Podcast episode with Marina Dubova (@mdubova.bsky.social)!
Apple podcast: podcasts.apple.com/us/podcast/n...

Stunning lecture („Antrittsvorlesung“) by @hilgerslab.bsky.social - friend, mentor and scientific inspiration at the very same time 😀 Happy that our paths join again in #Basel

The webinar series on spatial transcriptomics analysis is now open for registration!

Join me on 18 March to learn how we at @bayraktarlab.bsky.social integrate single-cell and spatial transcriptomics to map the rules of neurological conditions.

Why would Switzerland dissolve its Science Council? Saving no money and losing expertise which Swiss education, research and innovation need.
https://swr-web.vercel.app/en/blog/stellungnahme-des-swr-zu-seiner-geplanten-aufloesung

This poster is outside my little lab. There is nothing else like it. Please support this artist! @redpenblackpen.bsky.social

Head, Advanced Genomics Technologies Core Facility (Ref. CF/26/01) - IRB Barcelona IRB Barcelona invites applications for the position of&nbsp;Head, Advanced Genomics Technologies Core Facility. The successful candidate will report to the&nbsp;Director, Technology Strateg...

🚨WE'RE RECRUITING AT @irbbarcelona.org !!!!

--- ADVANCED GENOMICS FACILITY MANAGER ---

An amazing opportunity to help us drive the fight against cancer and other aging-related diseases using Single-cell, Bulk and Spatial genomics!!!!

APPLY NOW!!!!

recruitment.irbbarcelona.org/jobs/7124180...

A LinkedIn post from my profile, reading: “It's a very simple equation, really: Science communication needs to be accurate, it needs to be authentic, and it needs to be transparent. If you're not doing it that way, you're not doing science communication at all. In addition, *good* science communication is inclusive, it's ethical, it's sustainable. If you're not heeding these things, you're not doing science communication right. Which is why I am profoundly shocked by ostensibly reasonable people promoting the use of chatbots for science communication. Their use decreases factual accuracy. It decreases transparency. It decreases authenticity. Those things are true regardless of *which* chatbot you're using and regardless of *how* you're using it. Plus, the tech is not sustainable, not inclusive, not ethical. The promotion and use of Al chatbots is already damaging science communication and, if taken to the extreme, will be capable of quickly destroying it. Not through the rise of evil Al, but through ignorance on part of the users, rapidly destroying the trust that science communicators have been able to build over decades. Everything I will ever publish will be written by humans, and by humans only. If science communication goes the way of the robots, it will go there without me.”

LinkedIn probably wasn’t the best channel to post this, but I stand by it

Evolution of the median time under review of articles with female first authors, male first authors, female corresponding authors, and male corresponding authors.

#Women are underrepresented in academia, especially in #STEMM fields, top institutions & in senior positions. Analysis of millions of biomed & life science articles reveal that female-authored articles spend longer under review than comparable male-authored ones @plosbiology.org 🧪 plos.io/4658FZN

Nice sunrise over the Rhine in Basel! 🤩

🙏 to all who have contributed great ideas & motivational strategies to this thread. It’s clear that the effect of ongoing turmoil is heterogeneous; everyone, incl tenured professors, are facing changes, but those in transitional stages (looking for grad/postdoc/faculty positions) have it worst. 1/

Cartoon illustration showing the gap between Stegosaurus and T-Rex is about 90 million years, whereas between T-Rex and humans is "only" 65 million years. The T-Rex turns her head toward the human, licking her lips. The human is nervous, to say the least.

Visualising a fun fact.
#sciart

In remembrance of Peer Bork  | EMBL EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.

very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...

"C.ricketti, female from Jiangxi Province, China (CKYH), left: opisthosomal disc; right: details of radial ribs;" Source is given in thread.

Take a close look at this picture.

What an interesting coin or artifact, you probably think 🤔. Such interesting detail, intricately carved or molded 🧐 ... HAHA sucker, you're looking at a SPIDER'S BUTT.

Let's meet Cyclocosmia ricketti, the Chinese hourglass spider.

CW: spiders & their butts