The Gregory Lab @ DukeU

Privileged to have had the opportunity to advocate for biomedical research funding in #Congress yesterday! It was an honor to represent the @geneticssociety.bsky.social alongside my amazing colleagues @gregorylab.bskyverified.social and #JillFahrner! 🔬 🧠🧬
#ASHG #Genetics #ResearchMatters

Yesterday our leader @sgrayg.bsky.social, along with @lrizzardi.bsky.social & #JillFahrner advocated in #Congress on behalf of the @geneticssociety.bsky.social and described the amazing work #scientists are doing in the #NC districts! 🔬🧠🧬💻

#TedBudd #DeborahRoss #ValerieFoushee #ASHG #NorthCarolina

Engineers transform dental floss into needle-free vaccine New method places inactivated viruses directly into mice’s gums

Well this is really damn cool: Engineers transform dental floss into needle-free vaccine

www.science.org/content/arti...

Finding the perfect fit: How to choose the right single cell assay - 10x Genomics Find guidance to help decide on the right single cell assay for your experiments.

Unsure which #singlecell assay is right for your research? Our new blog post compares the capabilities of our Flex and Universal product families, from sample compatibility to time management, so you can find the best fit. Read now!

The @cellanome.bsky.social platform allows us to measure #temporal modalities of #cellular #phenotype and expression...

And the Gregory lab is so excited it's time to cell-ebrate these new insights! 🥳

Let us know if you have any questions about this exciting new technology🧬🖥️⚕️

New on Xenium: validated & ready-to-use protein panels! Now you can analyze 27 proteins alongside #spatial RNA for multiomic insights into #cancer, #immunology & more. Get a hands-on look with our interactive dataset & then pre-order your assay: bit.ly/4o0896R

Have any questions about adopting the @cellanome.bsky.social platform or our pilot projects? Interested in collaborating? Let us know!🧬

Last week, our fearless leader @sgrayg.bsky.social had the honor of speaking on the panel at @cellanome.bsky.social 1st customer forum event with @genomics-guy.bsky.social & Shawn Levy!

As an early access site for the #Cellanome instrument, we were invited to discuss our use of their platform. 🧬🔬💻

More than 13,000 Americans will be diagnosed with #glioblastoma in 2025, yet treatments and survival rates have remained largely unchanged for decades.

📣 This #GBMDay, reshare these stats to raise public awareness and inspire action.

Learn more: braintumor.org/events/gliob...

Spatial Transcript Omics DataBase (STOmics DB) is a comprehensive repository of literature and Datasets related to spatial transcriptomics topics, and provides convenient tools for Data analysis, search and visualization. db.cngb.org/stomics/

Figure summarizing the PuckerLab research interests. Source: https://www.pbb.uni-bonn.de

🚨 Seeking a brilliant postdoc for a Marie Skłodowska-Curie Fellowship! Work at the interface of bioinformatics, evolution & biotech.
🌱 Join a top German university
💡 Great science, strong mentoring
👉 www.izmb.uni-bonn.de/en/pbb/contact
#MSCA #Postdoc #Biotech #Bioinformatics #AcademicJobs

A comparison of long-read single-cell transcriptomic approaches. #LongRead #Sequencing #SingleCell #Transcriptomics #ToolsBenchmarking #Genomics #Bioinformatics @anitascoones.bsky.social @biorxiv-bioinfo.bsky.social 🧬 🖥️
www.biorxiv.org/content/10.1...

Come join us in Vancouver! Exciting opportunity for a more senior investigator researching new regenerative medicine approaches for Type 1 diabetes. $8M in funding for successful candidate research.ubc.ca/media/file/j...

Join us on July 15, for an educational webinar focused on the #Xenium platform. This session will cover:

🧬Technical concepts underlying the Xenium platform
👩🏽‍🔬The Xenium Panel Designer (XPD) design process
✏️Tips & tricks for designing new panels

Learn more and register at bit.ly/46pJCBI

Neuro-Immune Link Could Shape Brain Development, Study Finds Long seen as defenders against disease, immune cells in the brain are now emerging as architects of early brain development.

🧠 New Duke-led study in Immunity finds the brain relies on immune signals to form key connections.

Led by Dr. Staci D. Bilbo, the team discovered a chemical signal that may play a role in autism & Alzheimer’s.

Read more: medschool.duke.edu/news/neuro-i...

#AcademicSky #MedSky

📣 We are looking for a full-time research technician. This is a great opportunity for recent grads seeking additional hands-on experience before grad or med school. Join our team in exploring GPCR signaling and pharmacology at @dukemedschool.bsky.social Description: careers.duke.edu/job/Durham-R...

Late notice (due July 14th) but this RFI should be on people's radars:
"NIH is developing an institute-wide AI strategy that charts a progression from today’s data-science-driven analytics through semi-autonomous AI agents to fully autonomous, self-documenting biomedical AI beings."
#MedSky #MLSky

Discover the power of spatial transcriptomics with our on-demand webinar: "A Beginner's Guide to Spatial Transcriptomics." Learn how to map gene expression in spatial tissue contexts.

Watch now: bit.ly/3P5hWZ7

#SpatialTranscriptomics #GeneExpression #Genomics #CellBiology #ResearchInnovation

Cerebellum metastasis model of HER2-positive breast cancer unveils key role of IL34-induced Arg1+ macrophages Brain metastases occur in up to 40% of Stage IV breast cancer patients. The cerebellum is a frequent location for metastases in HER2-positive breast cancer patients, but the mechanisms for this are un...

Another Gregory lab collab, out now as a preprint!

'Cerebellum metastasis model of HER2-positive breast cancer unveils key role of IL34-induced Arg1+ macrophages', with #DukeMGC bioinformatician Khooshbu as 2nd author.

Congratulations to the whole team 🧬🔬💻⚕️

www.biorxiv.org/content/10.1...

a group of people inside of a lab, huddled around a computer

The AI tool Raygun (named as an homage to “Honey, I Shrunk the Kids”) is just one of several tools that a team led by Duke's Rohit Singh, PhD, has built to help scientists work both faster and smarter.

🔗 Read more: medschool.duke.edu/stories/hone...

#DukeB&B #DukeCellBiology #AcademicSky #MedSky

Stylized x ray featuring words: Diagnosis Young. The new face of cancer in NC. WRAL Documentary Thursday at 7:30 p.m.

“Cancer does not discriminate. It doesn’t care how young, how healthy, how fit you are.” Duke researchers & physicians work to uncover reasons more young people are diagnosed with cancer, & to develop new treatments to give patients a chance to become survivors.

#cancerawareness

Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD - Nature A comprehensive analysis of the cell-specific molecular regulatory mechanisms underlying post-traumatic stress disorder in the human prefrontal cortex.

New #publication out with #DukeMGC generated
@10xGenomics

#Xenium data from the Williamson lab - one of the first Xenium papers including #postmortem #PTSD samples! 🧠📷 #SingleCell #transcriptomic and #chromatin dynamics of the human brain in PTSD
www.nature.com/articles/s41...

Owkin and UNIL collaborators discuss the MOSAIC study: A conversation with Dr. Elo Madissoon and Dr. Raphael Gottardo - 10x Genomics We interviewed two of the scientists behind the MOSAIC study, a project that will leverage spatial biology and AI to develop targeted therapeutic strategies for cancer.

Read our interview with 2 of the scientists behind MOSAIC, a study that will generate a #Visium #spatialtranscriptomics dataset consisting of 7k+ patient tumor samples to advance therapeutic response modeling and #cancer #drugdiscovery. @owkin.bsky.social @unil.bsky.social

Moments from the #DukeMGC... lab work is fun with friends 🧬🤩🔬🧫👏

STAMP: Single-cell transcriptomics analysis and multimodal profiling through imaging @cellcellpress.bsky.social @lgmartelotto.bsky.social @hoheyn.bsky.social
www.cell.com/cell/fulltex...

Have you ever visited #DukeMGC's website?

If you're looking for more information on Duke's #MolecularGenomics #Core and the services we offer, please visit.... 🧬🧪🧫

dmpi.duke.edu/cores/molecu...

New posting for a Research Assistant in our division. Ideal position for recent graduate looking for experience in molecular neurobiology and microscopy. Team-oriented environment working across projects generating spatial transcriptomics data in human 🧠 tissue and human-derived neuronal cell models

#Throwback to the #SolarEclipse a few years ago...

The Gregory lab's future is so bright, we don't just need shades, we need eclipse glasses!!! 🧬🧠🤩🔬💻🧫

This summer @mssociety.bsky.social Undergraduate Summer Research Program placed a diverse group of undergrad students from around the country at @dukemedschool.bsky.social #MS labs to receive hands-on experience conducting MS research, 1:1 mentorship, and professional development opportunities 🧬🧠🔬💻🥼

How a discovery in Yellowstone National Park led to the development of PCR - Richmond Scientific A discovery in Yellowstone National Park led to the development of PCR, the gold-standard COVID-19 tests used to fight the global pandemic.

Reminder: Nobel-prize winning PCR (1983), used in basically all genetic tech today, was only possible because of extremophile bacterium discovered in 1964 in Yellowstone funded by a small ~$80k NSF grant with no obvious application at the time. #science 🧪
www.richmondscientific.com/how-a-discov...