Yiliang Ding

Biophysical Techniques Lecture Series 2025 - YouTube The LMB is home to a wide-array of scientific facilities, all of which work tirelessly to meet the research needs of LMB researchers.This playlist contains l...

The LMB is proud to be home to a wide array of scientific facilities, all of which work tirelessly to meet the research needs of LMB scientists. 🧪
Check out some of the biophysical techniques they offer in these talks on our YouTube channel: youtube.com/playlist?lis...

Many proteins bind RNA, yet we still don’t know what RNAs most bind because methods map one RBP at a time. In @cp-cell.bsky.social, with the Jovanovic lab, we describe SPIDR – a method for mapping the RNA binding sites of dozens of RBPs in a single experiment. www.sciencedirect.com/science/arti...

Calling all #RNA & #AI researchers! 🧬🤖 Submissions are open for the new open‑access collection “Exploring RNA Biology with Deep Learning Algorithms” in RNA Biology that I am guest editing with @yiliangding.bsky.social & Cliff Zhang. michaelwolfinger.com/blog/2025/bl... #DeepLearning #bioinformatics

Congratulations to all the prize winners from the Nucleic Acids Forum 2025! An amazing selection of talks and posters to choose from! Thank you to our prize sponsors Chemgenes and RSC Chemical Biology!
@rscchembio.rsc.org
@mikeboothlab.bsky.social

Me presenting my title slide for the event, with the wonderful sponsors!

an image of the ~130 attendees of the NAF!

It was a privilege to organise the 2025 RSC Nucleic Acids Forum at Burlington House last week - @rscnucleicacids.bsky.social!

The NAF has been my favourite event every year, so it was amazing to run it myself!

Full crowd, fantastic talks and posters, and a wonderful community 🧬❤️

plus some members who did not make it to the #2025NAF

Very honored to team up with @drmikebooth.bsky.social and @diantoniogroup.bsky.social to serve for the nucleic acids community @rscnucleicacids.bsky.social @rsc.org

@rscnucleicacids.bsky.social RSC nucleic acids new committee #2025NAF

As part of NAF 2025 we held a career event/panel discussion, sponsored by Glen Research! We are grateful to Stacey-Lynn Paiva, Hannah Pendergraff, and David Hammond for discussing their careers paths and all their advice! The session was chaired by our group's ECRs, Ellen Parkes and Vicky Kamperi!

Our final speaker of the day is Thomas Maher from Imperial College London, presenting his work on the “Interrogation of the nuclear G quadruplex interactome through SG4­directed proximity labelling“

Another event organised by our fabulous @rsc.org volunteers!

Career discussion #2025NAF @rscnucleicacids.bsky.social

Our final speaker of this session is Debashis Dhara from Oxford Univeristy, discussing "Synthesis and Properties of Densely Functionalised Charge Neutral Phosphothiotriester Oligonucleotides"

Highly collaborative efforts that involved 6 lab members and the labs of @yiliangding.bsky.social and @rdaslab.bsky.social. We uncovered a telomerase dimer and its potential role in telomere maintenance.

Our third speaker is Malou Coche from University College Doublin, talking on "Prodigiosin Modified Triplex-Forming Oligonucleotide Hybrids Enable Autocatalytic DNA Cleavage"

Next, we have Corinna Schlosser from UCL, discussing "Breaking barriers - Development of targeting peptides for enhanced delivery of antisense oligonucleotides to the brain"

Starting off our NAF 2025 meeting with an introduction of the RSC Nucleic Acids Group's new chair, Marco Di Antonio! An exciting new era for our group begins! 🧬
@diantoniogroup.bsky.social

Happy Nucleic Acids Forum!

Packed out at Burlington House today, as always.

Great to see the new leadership team of the Nucleic Acids Group in action ❤️

@rscnucleicacids.bsky.social
@rsc.org
@diantoniogroup.bsky.social
@yiliangding.bsky.social
@drmikebooth.bsky.social

Thank you 🙏

Structure of telomerase dimer with key catalytic codes and H/ACA RNPs highlighted with schematic illustrating how dimer disruption leads to shortened telomeres and disease mutations of the dimers causes premature ageing diseases

Sebastian Balch, Zala Sekne & Elsa Franco-Echevarría in @kellythd-nguyen.bsky.social's group have confirmed the existence of dimeric telomerase and illustrated how it is key to telomere maintenance:
www2.mrc-lmb.cam.ac.uk/first-struct...

#LMBResearch @yiliangding.bsky.social @rdaslab.bsky.social 🧪

Big congratulations to @kellythd-nguyen.bsky.social 👍👍👍Super beautiful structure👍👍👍Very happy to contribute some RNA structure work to this great collaboration😊 @johninnescentre.bsky.social @mrclmb.bsky.social

Independent Fellowship in Plant-Associated Microbial Interactions | John Innes Centre An exciting opportunity for an Independent Fellowship in Plant-Associated Microbial Interactions has arisen at the John Innes Centre. To read the full job description for this role…

New Independent Fellowship position in Microbiology to launch your lab in our department @johninnescentre.bsky.social (UK). We are conducting a broad search in the area of plant-associated microbial interactions. Message me if you have any questions.

Apply here: www.jic.ac.uk/vacancies/in...

It's a happy Monday when you realise a compound you discovered during your PhD is now commercially available!

TAP1 (forever etched into my mind) can disrupt G-quadruplex DNA structures and is now available from MedChemExpress
#chemsky

Dilek Guneri explains how DNA G-quadruplex structures appear to act like an on/off switch, whereas i-motif DNA structures act as a control dial in insulin gene expression at the Biochemical Society AlterNAT meeting

@biochemsoc.bsky.social
@rsc.org
@ucllifesciences.bsky.social

Shozeb Haider explains his love for Guanine at the Biochemical Society AlterNAT meeting.

What's your favourite nucleobase?

@shozebhaider.bsky.social
@rsc.org
@biochemsoc.bsky.social

#chemsky

Yiliang explains deep learning of nucleic acid structures - using an analogy of *babies* and *Shakespeare* at AlterNAT, hosted at RSC Burlington House

@biochemsoc.bsky.social
@rsc.org
@yiliangding.bsky.social

To kick off the final day of #Nucleic25, we had the pleasure of welcoming @lapassmore.bsky.social to the stage!
What better way to start the final day🌟

What an incredible few days it’s been with the amazing #Nucleic25 participants! 🌟
We can’t wait to celebrate all together at the Gala Dinner this evening! 🎉

🎉 Kicked off #Nucleic25 with Taekjip Ha talk on homology search in 3D genome, poster intros, and a dinner full of great conversations, new connections, and good food! 🧬✨