Dr Indranil Dev

Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis | NEJM In bronchiectasis, neutrophilic inflammation is associated with an increased risk of exacerbations and disease progression. Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1 (DPP...

Is there a better thing for a physician scientist than to have an impact on our patients - to take a previously ignored and hopeless disease and make it treatable?
Kudos Prof Chalmers ! What an amazing achievment!!! also 👏🏼to all #Aspen investigators 👏🏼
#CureBronchoiectasis
#ScienceMatters

A light blue diagram depicting the sea, with the water's surface at the top, and just below it is an outline of the Mary Rose, with the depth (12m, 40ft or 6.7 fathoms). There is a line showing the seabed, which takes a rapid dive into the vertical...

On the anniversary of the sinking of the Titanic, we thought we'd answer a question that's often asked,

"If they raised the Mary Rose, why not raise the Titanic?"

Allow our scaled diagram to explain...

My first post on BlueSky, I could not access the same handle as my X (someone hacked into that one):

So it's @peterhotez for X and @peterhotezmdphd for BlueSky

I'm a pediatric-vaccine scientist based in Houston TX at our Texas Medical Center

The Partition of India displaced 20 million people, killed almost 2 million & created a refugee crisis whose effects are still in play over 70 years later, if you actually think it's a model for anything but massive catastrophe, you should not only not be employed here you should be in a padded cell

Prevalence of Iron Deficiency and Iron-Deficiency Anemia in US Females Aged 12-21 Years, 2003-2020 This study examines prevalence of iron deficiency among females aged 12 to 21 years to inform future screening strategies for iron deficiency and iron-deficiency anemia.

If you’re feeling fatigued it could be existential doom or it could be iron deficiency.

One is much more easily treated so get those ferritins checked!

jamanetwork.com/journals/jam...

Nutritional care for TB-affected households is likely to be highly cost-effective & could avert a substantial amount of disease and death in India – our paper out now in Lancet Global Health @raclark18.bsky.social @reinhouben.bsky.social @lshtm-tbmod.bsky.social www.sciencedirect.com/science/arti...

The School Shootings Were Fake. The Terror Was Real The inside story of the teenager whose “swatting” calls sent armed police racing into hundreds of schools nationwide—and the private detective who tracked him down.

For two years, the serial swatter "Torswats" called in fake school shootings across the US, scrambling police, locking down schools, terrorizing hundreds of communities.

This is the untold story of his swatting rampage and the private eye who tracked him down. www.wired.com/school-swatt...

‘We have to be worried’: Top pediatric vaccine news of 2024 Routine childhood immunizations have prevented 1.1 million deaths in the United States since the CDC’s Vaccines for Children program launched in 1994, according to researchers.However, trust in ...

"Routine childhood immunizations have prevented 1.1 million deaths in the United States [since 1994]

However, trust in vaccines has eroded, leading to the reemergence of highly infectious diseases ..." www.healio.com/news/pediatr...
via @gohealio.bsky.social

Disinformation is one of the biggest threats to global health

Why I'm quitting the Washington Post Democracy can't function without a free press

Folks: please be diligent about not disseminating Ann Telnaes' cartoon in a way that she's not getting the clicks on it (until she says differently). Her IP matters now more than ever.

Make it go viral but make sure she benefits.

anntelnaes.substack.com/p/why-im-qui...

On 31 December 1995, Bill Watterson published the last ‘Calvin and Hobbes’ comic strip. It is a celebration of joy, friendship, and love, which is an appropriate reminder for kids of all ages at the start of every year.
#goexploring
#practicecourage
#LIVElife

A skull and neck partially embedded in the ground. Where the eye socket is, there is a large, black ball.

As we head into 2025, I'll be sharing 25 MEDICAL HISTORY OBJECTS starting with...

#1) 5,000-year-old prosthetic eye made of bitumen paste with lines radiating out from iris. Worn by a 6’ tall woman (possibly a priestess), found near the city of Zabol in Iran. The eye would have been painted gold.

Surgeons showed significantly greater manual dexterity compared with physicians, nurses, and non-clinical staff when assessed using a buzz wire game.

But had the highest rates of swearing
www.bmj.com/content/387/...

Happy New Year! 🥳

screenshot of reddit post showing a chai shop in india called ChaiGPT

Same in India!

MYTH: Drug companies apply for one patent per drug

FACT: Drug companies file dozens or even hundreds of patents on a single drug

ICU - Non-Invasive Ventilation (NIV) Secrets:

Did you ever admit to the ICU a patient with COPD exacerbation who came from the ED on NIV? Or who went home on NIV? If you are a pulmonologist, you can skip this post but, for the rest of us from different specialties (I am Internal Medicine),

This is a good thread on NIV.

I’m going to suggest some ways in which my practice differs from what is presented here. I don’t have any RCTs, but we try to consider physiologic plausibility (when has that ever failed?) and outcomes over time.

Between 1571 and 1573, Akbar moved the capital city to Fatehpur Sikri. The new city became the home of some of the most impressive architecture of Akbar’s reign and reflects a synthesis of Timurid traditions of Central Asia with indigenous traditions of Hindu and Muslim India.

She was one of SF's most decorated chefs. Now she feeds the Tenderloin for free Michelle Polzine closed her beloved 20th Century Café mid-Covid. Now she’s baking for anyone who needs a free meal.

This is so good. ❤️ sfstandard.com/2024/11/10/m...

Kal ho na ho !

"how can you block journalists" its actually really easy, all you have to do is click on those 3 dots on the right and it asks you right there

Prevalence of Iron Deficiency and Iron-Deficiency Anemia in US Females Aged 12-21 Years, 2003-2020 This study examines prevalence of iron deficiency among females aged 12 to 21 years to inform future screening strategies for iron deficiency and iron-deficiency anemia.

Just a reminder that iron deficiency is incredibly common

jamanetwork.com/journals/jam...

And reference intervals are garbage.

Join us at 2pm today #ASH24 in SDCC room 11 #ChoosingFairly to learn how you can work to change that!

#Aspirin Monotherapy vs No Antiplatelet Therapy in Stable Patients With Coronary Stents Undergoing Low-to-Intermediate Risk Noncardiac Surgery
(ASSURE-DES)

Article www.jacc.org/doi/10.1016/...
Editorial www.jacc.org/doi/10.1016/...
#CardioSky #JACC #MedSky
@jaccjournals.bsky.social

YouTube video by Dr. Glaucomflecken No More General Anesthesia

One thing I didn’t expect in the wake of the CEO shooting is the sudden attention on health insurance policy. I have seen this video and the BCBS policy itself go viral on almost every platform. People are waking up. Real lasting change in healthcare is coming. youtube.com/shorts/vWA2a...

T3a: #NephJC
🍯T2D pts with elevated SBP and ⬆️CV risk
♥️Intensive BP control reduced major CV events (HR 0.79 95% CI 0.69–0.9) over 5 yrs
⚠️Manageable increases in hypotension and hyperkalemia
💪Strengths: large sample, high adherence, minimal loss to follow-up, robust follow-up duration

@petchmo.bsky.social

Thanksgiving is a cranial nerve celebration! 🦃🧠 #neurosky

CN I: Smell the turkey
CN Il: See the feast
CN III, IV, VI: Keep eyes on the pie
CN V: Chew the stuffing
CN VII & IX: Taste the flavors
CN VIII: Hear the laughter
CN X: Digest it all
CN XI: Lift the turkey platter
CN XII: Toast your thanks