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Claire Gizowski

@clairegizowski.bsky.social

Senior Scientist in the brain aging team at Calico studying microglia and aging 🧠

60 Followers  |  90 Following  |  4 Posts  |  Joined: 28.01.2025  |  1.5243

Latest posts by clairegizowski.bsky.social on Bluesky

Data Explorer: Heterochronic myeloid cell replacement reveals the local brain environment as key driver of microglia aging

Have a peak at our interactive data explorer app tinyurl.com/Microglial-A...

08.09.2025 15:45 — 👍 0    🔁 0    💬 0    📌 0

Our new preprint!

"rejuvenation-by-replacement" might not work how we expect it to…

In short, we show the local brain environment drives microglia aging, with natural killer cells acting as an unexpected but necessary upstream player driving the age-dependent, stat1-mediated interferon response.

08.09.2025 15:45 — 👍 2    🔁 0    💬 1    📌 0
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Great way to end a week- our very first recordings with our brand spanking new 2photon microscope @brukercorporation.bsky.social 🥳🥳🥳 🔬🐭

~Nuclear tagged macrophages in mouse cortex in vivo

12.04.2025 01:18 — 👍 4    🔁 0    💬 0    📌 1
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Do you LOVE organelles??
Well I am THRILLED to announce that Nellie has been published in @naturemethods.bsky.social!

Nellie a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D, 3D, timelapse, multichannel live-cell microscopy

🧵1/N

27.02.2025 20:13 — 👍 188    🔁 74    💬 4    📌 10
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New ephys rig almost ready to rock 🤭 we’re so back

01.02.2025 01:09 — 👍 6    🔁 0    💬 0    📌 0

We lack tools to rapidly track >1-2 changing signals in brain fluids. Peter Kalugin and an amazing team begin to address this challenge with simultaneous, real-time tracking of many (10+) neuromodulatory signals using Multiplexed Optical Recording of Sensors on a micro-Endoscope. Feedback welcome!

27.01.2025 14:01 — 👍 19    🔁 5    💬 0    📌 1

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