Hunter Hill

Cheers!

Redesigning the Drosophila histone gene cluster: an improved genetic platform for spatiotemporal manipulation of histone function Abstract. Mutating replication-dependent (RD) histone genes is an important tool for understanding chromatin-based epigenetic regulation. Deploying this to

Crain, A. T., Nevil, M., Leatham-Jensen, M. P., ..., B., Matera, A. G., McKay, D. J., Duronio, R. J. (2024). Redesigning the Drosophila histone gene cluster: an improved genetic platform for spatiotemporal manipulation of histone function. Genetics, 228(1) academic.oup.com/genetics/art...

Sounds like a teaching opportunity!

Congratulations to both! I will miss seeing Ching-Ho at meetings and look forward to reading future papers from both labs.

I got my shirt and love it, thank you!! 😄

Very cool! Beautiful cytology

Introducing the 1,000 Flower Collection 🧬🌹

I’m creating 1,000 genetically designed flowers each crafted with new colors, patterns, and shapes.

Here’s how I’m making it happen… and how you can join me on this journey 🧵(1/7)

To promote the collection, I’ve launched a designer clothing line where synthetic biology meets aesthetics.

I will give out 100 free limited edition shirts to the first who retweet and order with their handle in the name! Available here → nickdesnoyer.com 🧵(6/7)

Looking forward to reading this!

Both are fun!

Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.

NEW: In an unprecedented move, the NIH will soon disinvite dozens of scientists about to take positions on advisory councils that make final decisions on grant funding.

NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.

I don’t think anyone is prepared for what they just did w/ ICE.

This is not a simple budget increase. It is an explosion - making ICE bigger than the FBI, US Bureau of Prisons, DEA,& others combined.

It is setting up to make what’s happening now look like child’s play. And people are disappearing.

Great dissection!!!

We had a system for this during my PhD and it worked well. Main issue is that its labor/time intensive. From wiping sharpie off the vials, autoclave, drill brush for cleaning in kitchen, and yes the vials eventually become deformed and opaque but we used cotton ball (not flugs).

Drosophila Genetic Database The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

#drosophila @flybase.bsky.social request emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!

www.philanthropy.cam.ac.uk/give-to-camb...

i encourage all to comment on the federal move to switch scientific staff to political appointees. this would be yet another disaster to the scientific process, unbiased pursuit of knowledge and medicine. deadline june 7.

www.federalregister.gov/documents/20...

www.regulations.gov/commenton/OP...

Treating a new Covid strain like a crime and not a public health issue is deranged.

I have found this very useful lately

Do not give them an INCH!

It's not: Well, maybe there are some areas where DEI has become too much a focus.
It's: FREE COUNTRIES DON'T SEND OUT BANNED WORDS LISTS TO THEIR SCIENTISTS

It's not: Well, science isn't perfect...
It's: FREE COUNTRIES DO NOT HAVE SCIENCE COMMISSARS

Summary of emerging technologies to study chromatin-protein interactions on native chromatin / in vivo.

🧬NEW review article from Henikoff and Ahmad about emerging epigenomic mapping technologies to study chromatin regulation. Very comprehensive - great for beginners and experts alike!

www.sciencedirect.com/science/arti...

For all the scientists who voted for Trump (and I know many of you), I hope the war on DEI was worth it.

Not weird at all!

If you're wondering why there's been so much insistence lately that COVID-19 was a lab leak, here's why: it is going to be an example for why all biomedical research & public health work should be defunded.

No evidence supports a lab leak, but it's used to justify cutting NIH's budget by 40%.

Gag proteins encoded by endogenous retroviruses are required for zebrafish development | PNAS Transposable elements (TEs) make up the bulk of eukaryotic genomes and examples abound of TE-derived sequences repurposed for organismal function. ...

💥🥳 At long last, our latest paper is out!

Gag proteins of endogenous retroviruses are required for zebrafish development

www.pnas.org/doi/10.1073/...

Led heroically by Sylvia Chang & @jonowells.bsky.social

A study which has changed the way I think of #transposons! No less! 🧵 1/n

It was awesome!!!!

Yes it was at the (now) Adam's Center and holds 7.5k. There were estimated~ 2k outside after it reached capacity

You may be fearing your 401k is no longer enough for you to retire. But with all the cuts to NIH and Medicare you also won't live as long. So the policies are integrated.

If only America would protect school children the way it protects Teslas.