Sergio Alcon-Rodriguez

TXNIP upregulation controls metabolism and cell cycle during androgen deprivation therapy in prostate cancer Cell Death & Disease - TXNIP upregulation controls metabolism and cell cycle during androgen deprivation therapy in prostate cancer

Here we show that androgens suppress TXNIP, which acts as a tumor suppressor in prostate cancer by regulating the cell cycle and glucose metabolism. As a result, TXNIP loss during androgen-deprivation therapy promotes tumor resistance 💊.

rdcu.be/ePmhY

23.11.2025 20:04 — 👍 0    🔁 0    💬 0    📌 0

🔬🍾 New publication! Happy to see part of my PhD work now published in Cell Death & Disease.

I am very grateful to everyone involved in making this happen.

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rdcu.be/ePmhY

23.11.2025 20:04 — 👍 0    🔁 0    💬 1    📌 0

First men invited to take part in most ambitious prostate cancer trial in decades First men invited to take part in the most ambitious prostate cancer trial in decades

The first men have now been invited to join the ambitious £42m TRANSFORM prostate cancer screening trial

It is co-led by six of the world’s leading #ProstateCancer researchers – including Professor Ros Eeles from the ICR.

Read more ⤵️

www.icr.ac.uk/about-us/icr...

21.11.2025 12:58 — 👍 0    🔁 1    💬 1    📌 0

After several intense and exciting years, I’ve finally defended my PhD! 🧬🎓 Huge thanks to my lab mates, my supervisors, family and friends for their support, and to the committee for their feedback and for making this day so special!! 🍾🍾

21.10.2025 09:06 — 👍 0    🔁 0    💬 0    📌 0