Carmen Buchrieser

Some #Pseudomonas aeruginosa strains naturally lack the major virulence system T3SS. 🦠 @inaattree.bsky.social & @cbuch.bsky.social labs reveal that avirulent isolates still produce valuable metabolites (e.g. rhamnolipids, elastase, pyoverdine)—making them promising for #biotech use.
buff.ly/JST7ZR1

Save the date! The @pasteur.fr Pasteur course on image analysis is announced:

It will happen from the 1st of June to the 5th 2026.

This year there will be only one track: the Early Career Investigator track (beginners). 👇

Mutations in the circadian cycle drive adaptive plasticity in cyanobacteria | PNAS Circadian clocks allow organisms to anticipate daily fluctuations in light and temperature, but how this anticipatory role promotes adaptation to d...

I am so proud to be part of this work, that we initiated Fernando de la Cruz and I, when he was on sabbatical in my lab in 2009... it took so much time for this achievement, 1000 thanks to Raúl Fernández-López! this brought me back to my PhD on cyanobacteria genetics. www.pnas.org/doi/10.1073/...

Plasticity of ventricle position after heart looping in heterotaxy with right isomerism The left/right position of ventricles needs to be maintained after heart looping, an unexpected step affected in heterotaxy.

New publication | Science Advances www.science.org/doi/10.1126/...

Die Infektionsforscherinnen Anja Lührmann, Sandra Reuter, Gabriele Pradel und Bärbel Stecher stehen stolz vor den Werbebannern von Infect-Net, Verband Deutscher Infektionsforscherinnen.

🔎 Find us at the 77th #DGHM Meeting in #Jena! Gabriele Pradel, Anja Lührmann, Sandra Reuter, Bärbel Stecher and others are happy to tell you more about our German network for women in infection research! 💜
👩‍🔬@gabrielepradel.bsky.social @sandrareuter.bsky.social @baerboletta.bsky.social

Phages are promising against antibiotic-resistant bacteria—but resistance can emerge. 🦠 New work from @baerboletta.bsky.social lab shows E. coli can resist phages in the lab, but in the gut that resistance comes at a cost: context is crucial for #PhageTherapy success.
buff.ly/NLOjnE2

Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols.
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🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫

Thread coming soon!

🇪🇺 Smooth publishing experience with #microLife, the new @femsjournals.bsky.social journal of the European Academy for Microbiology.

🙏 @erc.europa.eu, F.R.S-FNRS & WEL-RI for support
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Expanding the genetic toolbox of the obligate predatory bacterium Bdellovibrio bacteriovorus with inducible gene expression and CRISPR interference Inducible gene expression and CRISPR interference-mediated depletion in the predatory bacterium Bdellovibrio bacteriovorus.

🚨New paper out! #MicroSky
Studying obligate predators like Bdellovibrio bacteriovorus is tricky—essential genes for predation are also essential for survival.
We expanded its genetic toolbox:
🧬promoters to fine-tune expression
🧬IPTG-inducible system
🧬CRISPRi for rapid knockdown
bit.ly/46GUn2c
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Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters Uridine boosts aminoglycoside treatment efficiency against antibiotic-susceptible as well as antibiotic-resistant E. coli strains.

So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!

New preprint in the lab! How the mitochondrial ETC works during infection of human macrophages with #Legionella or #Salmonella? Spoiler: there are some similarities and also pathogen-specific differences. Work led by Francisco Garcia and Paula Martínez, with @cbuch.bsky.social at @pasteur.fr

🔬 We’re past the midpoint of the year; perfect time to look back at what’s been discovered so far. From how Salmonella slows its escape from immune cells to the microbes thriving in oil reservoirs, these are the most-read #microLife papers of 2025 so far: buff.ly/TfhOvEc

I was very honored to receive on of the Poster prizes at FEMS MICRO 2025 in Milan a few weeks back. It was such a great conference, heard so many interesting and stimulating talks & poster discussions.

Avirulent Pseudomonas aeruginosa T3SS-negative strains belonging to Clade 5 produce variable quantities of secondary metabolites Abstract. Pseudomonas species are ubiquitous in the environment and serve as valuable source of enzymes and secondary metabolites for industrial applicatio

Avirulent Pseudomonas aeruginosa T3SS-negative strains belonging to Clade 5 produce variable quantities of secondary metabolites

@femsjournals.bsky.social #microLife from @inaattree.bsky.social
with @cbuch.bsky.social

academic.oup.com/microlife/ad...

This 👇

Michael Patnode with Rachel Washburn, Jessica Aycock, and Mason Clark, winners of GRC MAST poster awards from Cell Press and FEMS

Congratulations to 2025 GRC Microbial Adhesion and Signal Transduction Poster Award Winners!! 🎆🥂🙌 Thank you @cp-cell.bsky.social and @femsmicro.org for sponsoring!

From,
Your secret judges 🤫

Congratulations @cbuch.bsky.social ! 👏

FEMS MICRO Milan 2025 is off to a great start with Prof. Carmen Buchrieser presenting her keynote on Legionella pneumophila and the fascinating ways this pathogen mimics eukaryotic cells.

What an inspiring first day at FEMS MICRO Milan! We heard from FEMS Pres. Antonio Ventosa at the Opening while former Pres. Hilary Lappin-Scott helped connect new attendees. Thanks to keynotes Profs. Carmen Buchrieser and Gian Rossolini for sharing their expertise. #FEMS2025

One of the most controversial sessions of the @femsmicro.org Congress—run by Malick Gibani—deals with the so-called *Human challenge studies* of pathogens ie deliberate inoculation of human subjects with virulent agents. The benefits are clear but … is informed consent enough 🤔?

Four leading researchers on bacterial computing in the @femsmicro.org Workshop on the the topic during the Congress—quite amazing talks by @angelgm.bsky.social, Yolanda Schaerli, Manish Kushwaha & Samgram Bagh. Do bacteria compute? Can we make them to compute wth our logic or do they have their own?

At my 1st @femsmicro.org congress (in Milan!) - it's a fantastic meeting. I co-chaired a superb session on Microbial Dark Matter with @jlewillett.bsky.social, who also kicked off the session with a talk on her lab's work. 🤩 We also heard from my FEMS Microbes co-EIC Kathleen Scott! 💪🏽 #FEMS2025

Delighted to have contributed to this fascinating paper led by Prof. Timmis on how helpful microbes can be for humanity at different scales! "The future is not set. There is no fate but what we make for ourselves". -John Connor (Terminator)
@microbiotech.bsky.social

New preprint from the lab!! Check it out!

The Respiratory Tract Microbiome and Human Health The respiratory tract microbiome (RTM) trains the immune system and protects against infections. Changes in the RTM are linked to various respiratory diseases. High-throughput methodologies and compu...

New mini-review on the respiratory microbiome and its contribution to human health from biotechnology 🫁🦠
@tmcoque.bsky.social @microbiotech.bsky.social
enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...

Thanks a lot Ana Elena

Congratulations to @cbuch.bsky.social on the FEMS-Lwoff Award!!! Well-deserved ❤️#FEMS2025

ᑎEᗯ IᑎᑎᗩTE IᗰᗰᑌᑎE EᖴᖴEᑕTOᖇ!

Anaya-Sanchez et al

Infected macrophages switch to aerobic glycolysis, generating toxic METHYLGLYOXOL

Bacteria lacking detox enzyme 𝘨𝘭𝘰𝘈 become highly mutagenic, lose virulence

Boosting methylglyoxal helps control 𝘓𝘪𝘴𝘵𝘦𝘳𝘪𝘢 or TB infection

www.cell.com/cell-host-mi...

🎶 Straight from the Lab to the Mic: when a Pasteur scientist turns her thesis into a rap 🎶
#FeteDeLaMusique