ATS G&G Section

Plasma nontargeted metabolomics study of H1N1 and H3N2 influenza in children https://pubmed.ncbi.nlm.nih.gov/40256448/

Smart contours: deep learning-driven internal gross tumour volume delineation in non-small cell lung cancer using 4D CT maximum and average intensity projections https://pubmed.ncbi.nlm.nih.gov/40251610/

A multidisciplinary approach towards modeling of a virtual human lung https://pubmed.ncbi.nlm.nih.gov/40251169/

Real-world application of targeted next-generation sequencing for identifying molecular variants in Asian non-small-cell lung cancer https://pubmed.ncbi.nlm.nih.gov/40247220/

RNase1-driven ALK-activation is an oncogenic driver and therapeutic target in non-small cell lung cancer https://pubmed.ncbi.nlm.nih.gov/40246819/

Carbon black induced pulmonary fibrosis through piR-713551/PIWIL4 targeting THBS2 signal pathway https://pubmed.ncbi.nlm.nih.gov/40246476/

Single-cell hdWGCNA reveals a novel diagnostic model and signature genes of macrophages associated with chronic obstructive pulmonary disease - PubMed The study provides new insights into the immune mechanisms of COPD and lays the theoretical foundation for its future clinical diagnosis and personalized treatment.

Single-cell hdWGCNA reveals a novel diagnostic model and signature genes of macrophages associated with chronic obstructive pulmonary disease https://pubmed.ncbi.nlm.nih.gov/40244418/

Unraveling the Immune Landscape of Chronic Obstructive Pulmonary Disease: Insights into Inflammatory Cell Subtypes, Pathogenesis, and Treatment Strategies - PubMed Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory disorder characterized by persistent airway inflammation and progressive airflow limitation, resulting in a significant global h...

Unraveling the Immune Landscape of Chronic Obstructive Pulmonary Disease: Insights into Inflammatory Cell Subtypes, Pathogenesis, and Treatment Strategies https://pubmed.ncbi.nlm.nih.gov/40244222/

Where lung cancer and tuberculosis intersect: recent advances - PubMed Lung cancer (LC) and tuberculosis (TB) represent two major global public health issues. Prior evidence has suggested a link between TB infection and an increased risk of LC. As advancements in LC trea...

Where lung cancer and tuberculosis intersect: recent advances https://pubmed.ncbi.nlm.nih.gov/40242762/

Lung-specific metastasis: the coevolution of tumor cells and lung microenvironment - PubMed The vast majority of cancer-related deaths are attributed to metastasis. The lung, being a common site for cancer metastasis, is highly prone to being a target for multiple cancer types and causes a h...

Lung-specific metastasis: the coevolution of tumor cells and lung microenvironment https://pubmed.ncbi.nlm.nih.gov/40241074/

Analysis of the bronchoalveolar lavage fluid microbial flora in COPD patients at different lung function during acute exacerbation https://pubmed.ncbi.nlm.nih.gov/40240456/

Comparative effect of different corticosteroids in severe community-acquired pneumonia: a network meta-analysis https://pubmed.ncbi.nlm.nih.gov/40307783/

Physiological signal entropy in patients with chronic respiratory disease: a systematic review - PubMed The review highlights the potential of entropy analysis of physiological signals for early detection of COPD exacerbations and for differentiating between various levels of disease severity in both CO...

Physiological signal entropy in patients with chronic respiratory disease: a systematic review https://pubmed.ncbi.nlm.nih.gov/40306956/

Prospective follow-up of New York City residents with e-cigarette, or vaping product use-associated lung injury-2020-2021 - PubMed NYC residents with EVALI reported symptoms throughout the follow-up period, and approximately half reported newly diagnosed health conditions. Further studies are needed to understand EVALI's relation...

Prospective follow-up of New York City residents with e-cigarette, or vaping product use-associated lung injury 2020-2021 https://pubmed.ncbi.nlm.nih.gov/40305486/

Application and research progress of artificial intelligence in allergic diseases https://pubmed.ncbi.nlm.nih.gov/40303497/

Analytical validation of total mucin concentration assay using SEC MALLS dRI for diagnosing and monitoring mucoobstructive lung diseases - PubMed Mucins play a pivotal role in the pathophysiology of mucoobstructive lung diseases. Accurate quantification of total mucin concentrations in clinical sputum samples is critical for developing objectiv...

Analytical validation of total mucin concentration assay using SEC MALLS dRI for diagnosing and monitoring mucoobstructive lung diseases https://pubmed.ncbi.nlm.nih.gov/40301448/

Systematic Review and Meta-Analysis of the Association Between Clinical Severity and Co-Infection of Human Adenovirus With Other Respiratory Pathogens in Children - PubMed The correlation between the co-infection of human respiratory adenovirus (HAdV) and clinical severity has not been firmly established yet. We carried out a systematic review and meta-analysis. We scou...

Systematic Review and Meta-Analysis of the Association Between Clinical Severity and Co-Infection of Human Adenovirus With Other Respiratory Pathogens in Children https://pubmed.ncbi.nlm.nih.gov/40297972/

Mechanical stress facilitates calcium influx and growth of alveolar epithelial cells via activation of the BDKRB1/Ca2+/CaMKII/MEK1/ERK axis - PubMed Appropriate levels of mechanical stress contribute to the growth and calcium influx of alveolar epithelial cells by modulating BDKRB1/Ca²⁺/CaMKII/MEK1/ERK signaling.

Mechanical stress facilitates calcium influx and growth of alveolar epithelial cells via activation of the BDKRB1/Ca2+/CaMKII/MEK1/ERK axis https://pubmed.ncbi.nlm.nih.gov/40296124/

Low levels of DNA repair enzyme NEIL2 May exacerbate inflammation and genomic damage in subjects with stable COPD and during severe exacerbations - PubMed Not applicable.

Low levels of DNA repair enzyme NEIL2 May exacerbate inflammation and genomic damage in subjects with stable COPD and during severe exacerbations https://pubmed.ncbi.nlm.nih.gov/40296120/

Check out @saahimall.bsky.social's #skysplain of our latest work! Very proud of all her hard work on this study and REALLY excited for what she's got planned next!

#bpd #lungdevelopment #genomics #science

#Medsky🧪 #IDsky #immunosky Macrophages are versatile innate immune cells that act as sentinels, warriors & healers in virtually every tissue. This review on current insights into their developmental origins and the organ-specific cues that imprint diverse tissue-resident & monocyte derived programs

#ATS2025 featured cutting-edge technology, engaging educational sessions, and the opportunity to connect with the respiratory health community.

Multi-omics characterization of early chronic obstructive pulmonary disease - PubMed Chronic obstructive pulmonary disease (COPD) is projected to become the third leading cause of death globally by 2030, accounting for 71.9% of chronic respiratory diseases cases in 2019. Early COPD (E...

Multi-omics characterization of early chronic obstructive pulmonary disease https://pubmed.ncbi.nlm.nih.gov/40296012/

Dissecting cross-population polygenic heterogeneity across respiratory and cardiometabolic diseases https://pubmed.ncbi.nlm.nih.gov/40295474/

Healthful Plant-Based Dietary Patterns Associated with Reduced Adverse Effects of Air Pollution on COPD: Findings from a Large Cohort Study https://pubmed.ncbi.nlm.nih.gov/40292512/

An Automated Algorithm for Obstructive Sleep Apnea Detection Using a Wireless Abdomen-Worn Sensor - PubMed Obstructive sleep apnea (OSA) is common among older populations and individuals with cardiovascular diseases. OSA diagnosis is primarily conducted using polysomnography or recommended home sleep apnea...

An Automated Algorithm for Obstructive Sleep Apnea Detection Using a Wireless Abdomen-Worn Sensor https://pubmed.ncbi.nlm.nih.gov/40285102/

snCED-seq: high-fidelity cryogenic enzymatic dissociation of nuclei for single-nucleus RNA-seq of FFPE tissues https://pubmed.ncbi.nlm.nih.gov/40316516/

The role and machine learning analysis of mitochondrial autophagy-related gene expression in lung adenocarcinoma - PubMed COASY, FTSJ1 and MOGS have emerged as critical biomarkers in LUAD, potentially influencing tumorigenesis through mitophagy-related mechanisms and immune modulation. These findings provide promising av...

The role and machine learning analysis of mitochondrial autophagy-related gene expression in lung adenocarcinoma https://pubmed.ncbi.nlm.nih.gov/40313958/

Multi‑omics analysis identifies different molecular subtypes with unique outcomes in early-stage poorly differentiated lung adenocarcinoma https://pubmed.ncbi.nlm.nih.gov/40312720/

Artificial intelligence driven 3D reconstruction for enhanced lung surgery planning - PubMed The increasing complexity of lung surgeries necessitates the need for enhanced imaging support to improve the precision and efficiency of preoperative planning. Despite the promise of 3D reconstructio...

Artificial intelligence driven 3D reconstruction for enhanced lung surgery planning https://pubmed.ncbi.nlm.nih.gov/40312393/