Jeremy Labrecque's Avatar

Jeremy Labrecque

@jeremylabrecque.bsky.social

Canadian epidemiologist and causal inference person at Erasmus Medical Center. Big fan of Northern Expsoure and Car Talk. jeremylabrecque.org

2,476 Followers  |  1,209 Following  |  908 Posts  |  Joined: 01.12.2023  |  2.2907

Latest posts by jeremylabrecque.bsky.social on Bluesky

Yes. You just have to make sure you haven’t induced any biases by conditioning on that subgroup.

09.12.2025 15:54 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Or could conceivably be pregnancy but not birth (loss or given away to adoption). there are many potential meanings of the effect of birth.

09.12.2025 15:52 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Yeah, that is the tough question! Even if you ask a question only about the effect of birth, you can’t have a birth without also having been pregnant (well, you could adopt) so pregnancy is necessarily part of the treatment. And the control arm could either be no birth or pregnancy

09.12.2025 15:52 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Shhhh! Don't anger the gods of perinatal research!

I think there are potentially some issues though with the precise research question and with competing events (infertility, losses) but my own eyes are rolling as I write this so I'll just keep them to myself.

09.12.2025 13:49 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Ignore the competing events of perinatal epidemiology at your peril!

09.12.2025 12:34 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Particularly because I've been in rooms where people say "let's plug that estimate into our model." When I tell them you can't because it's from a predictive model they say "but surely having some number and being able to run our model is better than having no number."

09.12.2025 09:05 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Yeah, my feeling as well. I think they might be useful to find dynamics that we might not find otherwise but I'm really skeptical about their ability to estimate magnitudes of causal effects.

09.12.2025 09:05 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

I hope you're successful in getting people to think about their controls!

09.12.2025 09:02 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

My suggestion was going to be to simulate the DAG to check. But even better is to post it on bluesky and wait for people like @stephenjwild.bsky.social to do the simulation for you!

09.12.2025 09:01 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Or am I missing something here?

08.12.2025 20:54 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

nice work on the paper. But for this one, adjusting for the parent shouldn’t adjust (even partially) for the descendent. The inverse is true: adjusting for the descendent partially adjusts for the parent. We would be in big trouble if we could never adjust for variables that influenced mediators!

08.12.2025 20:53 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I’m just an astronomy nerd so I was pumped about this one

08.12.2025 20:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I don’t get this one. Why is adjusting for judge characteristics a problem on this DAG? And why (or how) is judge prejudice being conditioned on?

08.12.2025 17:15 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Did not think I could enjoy M estimator more until you added in astronomy

08.12.2025 15:44 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I like this! But what are the identification assumptions when the research question is an association?

07.12.2025 21:46 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

How often do you see in an intro section the authors making a clear distinction bw causal papers they cite and observational ones? All seem to be magically causal. πŸ€”

07.12.2025 15:52 β€” πŸ‘ 25    πŸ” 4    πŸ’¬ 4    πŸ“Œ 1

Thereβ€˜a just no way to get any shred of evidence for a causal effect (even if that evidence is just something that makes you slightly more likely to do a second study) without inputing some kind of causal assumption.

But maybe I’m totally out to lunch!

07.12.2025 21:22 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

The way I think about this is it only works if you can argue that if X does not cause Y you would have been less likely to observe an association. Which is an argument about the potential absence of biases which is, therefore, a causal argument!

07.12.2025 21:22 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I get most of mine while running or cycling. I had a bad knee injury for a while and I was worried I wouldn't be to run and therefore not have any new ideas.

06.12.2025 21:31 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I both approve and am extremely envious!

05.12.2025 22:43 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Something something Dahlphi process

05.12.2025 22:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I particularly like jokes in a peer review where I’m forced to be really critical because I hope it conveys a message like β€œlook, iβ€˜m being tough here but it’s nothing personal. You still deserve a chuckle.”

05.12.2025 16:15 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

We don’t just assume new treatments will work, we test them thoroughly.

Why do we think we can just throw AI at a problem and it will just work?

05.12.2025 12:22 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

And more jokes during the peer review process. I always like to include one or two

05.12.2025 12:16 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

People rarely check the positivity assumption but I’d say 5% of the time it shows something strange is going on that we wouldn’t have caught otherwise.

04.12.2025 08:01 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Will this be my chance to buy you a beer?

02.12.2025 21:57 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I also feel better inside when DAGs flow from left to right.

02.12.2025 21:00 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I could almost tell you the day AI was incorporated into autocorrect. The change was that drastic. Started automatically changing the word β€œthe” to tge. (and right now it autocorrected to thΓ© even though I’m using an English keyboard

01.12.2025 16:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

"Unusually insightful" is a perfect way to put it.

01.12.2025 15:33 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you for making me aware that this exists

29.11.2025 22:17 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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