Aniek Janssen

Ready to establish your own research group at the Hubrecht Institute for Molecular and Developmental Biology? We’re seeking a tenure-track group leader to develop an innovative research line within our vibrant scientific community. Learn more & apply! https://f.mtr.cool/jncxfqkuds

An electrostatic repulsion model of centromere organisation During cell division, chromosomes reorganise into compact bodies in which centromeres localise precisely at the chromatin surface to enable kinetochore-microtubule interactions essential for genome se...

1/ New preprint alert!
In collaboration between the Rosen, Redding, Collepardo-Guevara & Gerlich labs, we uncover a surprising principle of chromosome organisation: electrostatic repulsion positions centromeres at the chromosome surface during mitosis.
🔗 doi.org/10.1101/2025...

Please please please, if you are able, consider supporting Flybase fiscally. They need our help! I donated this evening. They are in danger of closing and any amount will help. We cannot allow this critical pillar of science to collapse!

Harvard University lays off fly database team The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.

FlyBase, a Drosophila database, will lose a third of its team in early October because the Harvard grant that covered the employees’ salaries was canceled. Scientists warn that losing FlyBase could devastate fly research.

By @claudia-lopez.bsky.social

www.thetransmitter.org/community/ha...

WORK!

I currently have 5 (!) open positions for postdocs/PhD students in our CDlab for projects:

- Nanopore protein sequencing
- Archaeal CDV cell division
- Microfluidics for synthetic cells
- Nuclear Pore Complex
- Origami mimics of peroxisomes

Please apply! ceesdekkerlab.nl/come-join-us/

RT=👍

MRC Postdoctoral Research Scientists x 5 - MRC Laboratory of Medical Sciences Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.

Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc!

Multiple positions across multiple groups @mrc-lms.bsky.social

Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇

lms.mrc.ac.uk/work/vacanci...

Retrospective and multifactorial single-cell profiling reveals sequential chromatin reorganization during X inactivation - Nature Cell Biology Kefalopoulou, Rullens et al. develop Dam&ChIC to assay chromatin state at two different time points in the same cell. The method was used to study the reorganization of LADs during cell division a...

I am very excited to share our latest work where we describe a new method to profile genome-wide chromatin transitions over time in single cells. Great collaborative effort with the van Oudenaarden group @hubrechtinstitute.bsky.social @oncodeinstitute.bsky.social www.nature.com/articles/s41....

Congratulations Leo!!

WHAT?! hahaha, haven't seen anything like that for fly people no ;P

Advancing cancer research via comparative oncology Nature Reviews Cancer - Comparative oncology combines evolutionary biology, ecology, veterinary medicine and clinical oncology to better understand cancer, for example, by identifying the molecular...

Happy to share a new publication: an introduction to comparative oncology in @natrevcancer.nature.com‬. Thanks to the leaders in the field for welcoming me as an invertebrate researcher.
rdcu.be/etKdN

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature Communications Redox signalling is emerging as an important regulator of metabolism and physiology, which is dysregulated in ageing and disease. Here, the authors show that redox regulation of a key redox sensitive ...

🎉Excited to share our latest paper, published in Nature Communications!🎉

"Enhancing autophagy by redox regulation extends lifespan in Drosophila"

#redox #metabolism #ageing #Drosophila

@natcomms.nature.com @mrc-lms.bsky.social

doi.org/10.1038/s414...

Please consider donating to help maintain FlyBase

Postdoctoral Research Associate in the Blackford Group A position as Postdoctoral Research Associate is available at the Department of Cellular and Molecular Medicine, in the group headed by Dr. Andrew Blackford. Th

We’re #hiring, please share! A fully funded #postdoc position is available in my lab to work on DNA damage response mechanisms.

Please get in touch with your CV if you are interested; closing date: 27th June 2025.

More details here: candidate.hr-manager.net/ApplicationI...

If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social

A few days left to apply for exciting PhD and Postdoc opportunities in wonderful Copenhagen and join our efforts in understanding Epigenetic Cell Memory.

🔥New Night Science paper!!
Discovery happens when your initial plans fall apart but it requires you to have a particular mindset: it's not extraverted, orderly, neurotic or agreeable that's the most important – discovery requires an OPENNESS to new ideas and unexpected insights.

Who does that? We rented a train JUST for the conference, that will take the participants from Prague to the woods of Bohemia. There'll be talks ON THE TRAIN. In Prague we'll have 5 locations with different atmospheres.
#theconferencetoendallconferences Register now:
woodstock.img.cas.cz

Gender equality doesn’t just 'happen.'

Women’s rights must be fought for and protected.

Our responsibility is clear.

To lead by example and create a world where opportunities are fair for all.

Not just today, but every single day.

#InternationalWomensDay

Post-doc in fungal molecular cell biology. Seeking person with an understanding of gene expression and phenotypic analysis, who is interested in epigenetic regulation in fungi, to explore mechanisms of antifungal resistance in Zymoseptoria tritici and Schizosaccharomyces pombe. Email me! #ECFG17

For all of you who cannot access pubmed, here is a good alternative:
europepmc.org

It seems PubMed has disappeared. This is the digital equivalent of burning a library.

Disabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viability Losing parental histones during DNA replication fork passage challenges differentiation competence and cell viability.

𝐇𝐨𝐰 𝐝𝐨 𝐜𝐞𝐥𝐥𝐬 𝐫𝐞𝐦𝐞𝐦𝐛𝐞𝐫 𝐰𝐡𝐨 𝐭𝐡𝐞𝐲 𝐚𝐫𝐞 𝐚𝐟𝐭𝐞𝐫 𝐃𝐍𝐀 𝐫𝐞𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧? Our new study “Disabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viability” is out in 𝘚𝘤𝘪𝘦𝘯𝘤𝘦 𝘈𝘥𝘷𝘢𝘯𝘤𝘦𝘴. Led by @lleonie.bsky.social @biranalva.bsky.social 🧵 More below👇

Very happy to share that our work on identifying and characterizing factors affecting DNA replication is published by Nature Communications!

Center for Molecular Medicine

Our Center for Molecular Medicine (cmmutrecht.eu) at UMC Utrecht, NL, is looking for a Principal Investigator in the field of fundamental Cancer Biology! The vacancy states tenure track level, but candidates with a more advanced career are very welcome to apply. shorturl.at/KZeYQ. Please repost!

Long-term imaging of individual ribosomes reveals ribosome cooperativity in mRNA translation Ribosomes cooperate through transient collisions to ensure efficient translation.

Our paper on Stopless-ORF Circular RNAs (socRNAs) is now out in Cell. By high-res tracking and comparing translation by either single or multiple ribosomes, we find that ribosomes cooperate to overcome pausing to ensure fast and efficient translation

www.cell.com/cell/fulltex...

Congrats Agathe & lab!! 🙌

Article on the mass eXit of German universities from plattform X in protest against anti-democratic discourse pushed by Elon Musks algorithms.

This is a turning point.

We Europeans have the power to push X into irrelevance across our continent. Freeze or delete your accounts now.

Media, it’s time to stop citing X.

Dozens of universities are leading the way. Let’s limit Elon Musk’s influence in 🇪🇺.

#eXit #SciXit #Democracy

6 more weeks to apply !

Become our new colleague at the Cell Biology Dpt and join the growing group of junior teams of @i2bcparissaclay.bsky.social shaping the scientific environment of the institute.

Apply if you are looking for a place to start a lab or forward to any potential candidates.

Are you aware of our collection of #Drosophila #history articles? Feel free to suggest more!!!!!!!! droso4public.wordpress.com/history/

Very excited to see our work on genome-wide mapping DNA repair in single cells out @naturecomms.bsky.social
Amazing work by Kim de Luca & Pim Rullens. Wonderful collaboration with the Legube lab, @mariekeoudelaar.bsky.social & @jjachowicz.bsky.social . rdcu.be/d0ZAM