Anne-Clemence Vion

NET1/ARHGEF8 is a mechanosensitive Guanine Exchange Factor controlling vascular smooth muscle cells' contractility Cyclic stretch, generated by pulsatile blood pressure, has been identified as a pivotal regulator of vascular smooth muscle cell (VSMC) behavior and arterial wall homeostasis. Research has demonstrate...

🔬 New preprint !!! 👇
📃 shorturl.at/uTj8m
🧫 We identified NET1/ARHGEF8 as a stretch-sensitive RhoGEF in smooth muscle cells
Thanks to Mary-Adel Mrad and the team for their hard work 💪
#vascularbiology #smoothmusclecell #cyclicstretch↔️
@inserm.fr @cnrsbiologie.bsky.social

#EVBOSeminarSeries Moderated by Joanna Kalucka. Speakers: Ralf Adams and Mariona Graupera. ⏰When: Wednesday, 18th June 2025, 3PM EU time (2PM UK). Place: online. See you there! For registration evbo.org

#EVBOSeminarSeries Moderated by Mara Pitulescu. Speakers:
Valeria Orlova, Anne Eichmann and João Cardeira da Silva. ⏰When: Thursday, 5th June 2025, EU time (2PM UK). Place: online. See you there! For registration www.evbo.org

ARHGEF18 is a flow-responsive exchange factor controlling endothelial tight junctions and vascular leakage Batta et al. identified ARHGEF18 as a flow-responsive RhoGEF with high phosphorylation-dependent activity under physiological shear stress and as necessary to maintain tight junctions by recruiting ZO...

It’s out ! My first last author paper 🥰…
We identified ARHGEF18 as a flow responsive protein participating in vascular barrier maintenance 🔬🧫
Congratulations to the whole team, especially Surya Batta, PhD at that time in the lab !
www.cell.com/cell-reports...
@inserm.fr @cnrsbiologie.bsky.social

Vacatures - PhD vascular cell biology - Amsterdam UMC Are you a motivated researcher with a passion for cell biology and blood vessels? Do you want to uncover the molecular mechanisms that drive vascular function? Join our team and apply now!

Interested in research on cell-cell junctions and vascular biology? We are recruiting a PhD student!

werkenbij.amsterdamumc.org/en/vacatures...

HAPPENING TOMORROW!! #EVBOSeminarSeries Moderated by Maria Ulvumar. Speakers:
Sarah De Val, Matthew Campbell and Ashik Ahmed Abdul Pari. ⏰When: Wednesday, 5th February 2025, EU time (2PM UK). Place: online. See you there! For registration www.evbo.org

#EVBOSummerSchool 2025: Please help spread the news!
10-11 June 2025 | Biomedicum Helsinki, Finland
Registration will open soon. Stay tuned!
The summer school will be preceded by the excellent and free-of-charge Wihuri Research Symposium on Cardiovascular Biology!

More info buff.ly/42I9fvY

This is what happens when you lab engineer is also the owner of a bar… ♥️ #bestteam #science #cocktailevening #vascularbiology

ANGPTL6 variant induces cerebral vascular dysfunction and predisposes to intracranial aneurysm in mice Background: Intracranial aneurysm (IA) is a common cerebrovascular abnormality characterized by localized dilation and wall thinning in intracranial arteries, that frequently leads to fatal sub-arachn...

Happy to share our new preprint ! We studied how a genetic variant favors intracranial aneurysms in mice.
#vascularbiology #aneurysms @chunantes.bsky.social
@cnrsbiologie.bsky.social @insermgrandouest.bsky.social
www.biorxiv.org/content/10.1...

Great PhD defense by Tom Lecorvec, vascular surgeon who did his scientific thesis in our lab ! Smooth muscle cells rock 💪
@chunantes.bsky.social, Nantes university, L’institut du thorax

Brain vascular imaging in live animal… 3D-ULM rocks !
Great talk by Olivier Couture at the « folle journée de l’anévrisme »

Giving a open conference for the general public tonight on Intracranial Aneurysm 🧠
Together with Romain Bourcier, neuroradiologist @chunantes.bsky.social
@inserm.bsky.social @cnrs.bsky.social

The crew !

As usual in December, our institut is doing the “advent offices” which consiste in one office each day is providing treats and food for the rest of the institute.
Today is our day 😋 🥰

Amazing defense and stimulating discussion! Well done Clémence and thank you @team6lvts.bsky.social for making me part of this jury

Ça se passe mercredi prochain !
@institut_thorax @Inserm @NantesUniv @CNRSbiologie