Hellmut Augustin

Exciting new work for the Angiopoietin aficionado: Angiopoietin dysregulation as early hallmark of amyloid- driven vascular dysfunction in Alzheimer's disease. Must read work from the Wysscoray and Keller laboratories published on @biorxivpreprint.bsky.social.

Three new @erc.europa.eu Starting Grants for vascular researchers: Congratulations to Vanessa Coelho-Santos (@vcoelhosantoslab.bsky.social) for "AngioArchitects“ (LS5], Leire Bejarano for "MetaVasc" (LS4], and Mahak Singhal for "Vascular Rhythm" (LS4). Great success!

Congratulations to Mahak Singhal @uniheidelberg.bsky.social on being awarded an @erc.europa.eu Starting Grant for his project "Vascular-Rhythm" focussing on "DeClocking the vascular rhythmic control of tissue homeostasis and disease initiation". Pioneering a new branch of vascular research!

2025 has been an intense and in part rough year. Time to let body and soul heal and recover. Found a wonderful place overlooking Costa Adeje on the lovely island Tenerife (www.oceanviewmontesol.com). Spectacular view – plenty activities – great new ideas - feels like rejuvenation - check it out!

Still time to apply to the 2 open 6-year Junior Group Leader positions at the European Center for Angioscience (ECAS) at Heidelberg University. Application deadline is September, 10, 2025.

Interested in pursuing a postdoc in the Augustin lab at the German Cancer Research Center in Heidelberg (www.augustinlab.de)? Working at the interface of angioscience and metastasis. Apply to the DKFZ postdoctoral fellowship program (www.dkfz.de/en/karriere/...). Deadline: Sept. 15, 2025.

Spread the word: The European Center for Angioscience @uniheidelberg.bsky.social continues to grow: We have openings for 2 additional Junior Group Leader positions. Get in touch with us if you are ready to start your own lab. See also corresponding ad in @nature.com: www.nature.com/naturecareer...

Following our epigenetic placental vasculature paper in Dev Cell‬ (www.sciencedirect.com/science/arti...), the second chapter of our vascular epigenetic trilogy was now published in @narjournal.bsky.social‬ (academic.oup.com/nar/article/...): DNMT3A regulation of EC enhancer landscape. More to come!

Don Nguyen, PhD, (center) chaired an Education Session at #AACR25 on Non-Genetic Drivers of Cancer Metastasis featuring @hellmutaugustin.bsky.social and Dr. Ashley Laughney. @theaacr.bsky.social @yalepathology.bsky.social

Another hyped study published in Nature Medicine claiming to have developed a predictive test for the identification of women at risk of developing preeclampsia. Sobering: The predictive value is no better than the cheap routine measurement of sICAM-1 and sVCAM-1 reported more than 20 years ago.

Gratifying to now see our pericrine liver signaling work in the print version of @Nature.com (www.nature.com/articles/s41...). Massive piece of work with 651 display items (174 main, 477 supplement). Feels like we are publishing books and not papers. Thanks to Robert Schwabe for great collaboration!

Angiocrine signaling is rocking - pericrine signaling is the new kid on the block: Hepatic stellate cells control liver function (‘HSCs make the liver great again’) - now published @nature.com (www.nature.com/articles/s41586-025-08677-w). Fantastic collaboration with the Schwabe lab at Columbia Uni

Spectacular hemangioma work from Joyce Bischoff's lab in @jclinical-invest.bsky.social. Fantastic basic science (discovery of SOX18-mevalonate pathway) combined with great translational perspective (drug repurposing). Congrats to Anne Holm! Check it out: dm5migu4zj3pb.cloudfront.net/manuscripts/....

Epigenetic regulation of placental vascularization - now published in Developmental Cell (www.sciencedirect.com/science/arti...). Congratulations & thanks to Stephanie Gehrs for fantastic work and paving the way of the www.augustinlab.de into the world of vascular epigenetics. There’s more to come!