Huber Lab @ RU Bochum

Early Career Research (ECR) Group Leader position (m/f/d) with the thematic focus on “Catalysis” within the Cluster of Excellence RESOLV

Please check this announcement for an early-career group leader, hosted jointly by our cluster of excellence RESOLV and the MPI Kofo. The thematic focus should be on catalysis: jobs.ruhr-uni-bochum.de/jobposting/4...

Biaxial Recognition: Towards Chiral Resolution of Allene-Dicarbonyl Compounds by Iodolium-Based Halogen Bond Donors The coordination of allene dicarbonyl compounds to cyclic iodonium salts is presented as a new biaxial halogen bonding recognition motif. 1H¬ NMR titrations and isothermal titration calorimetry (ITC) ...

(here is the link:) chemrxiv.org/engage/chemr...

In a preprint, we report a particularly interesting substrate for biaxial halogen bonding with iodine(III)-based Lewis acids: allenes. We also introduce chiral variants which allow enantiodiscrimination of allenes via NMR:

At the end of August, we said goodbye to Julian Wolf, former PhD student and postdoc. Thanks a lot for your contributions, particularly all the work to establish highly enantioselective XB catalysis, and all the best!

Paris said au revoir to cars. Air pollution maps reveal a dramatic change. Air pollution fell substantially as the city restricted car traffic and made way for parks and bike lanes.

Wow. Check this out.
Politicians actually trying to solve problems can achieve a lot!
www.washingtonpost.com/climate-solu...

Yes, I like how the viewing angles combine (by chance)

We welcome Katyayani and Jelke as new PhD students to our group - both will explore different aspects of halogen and chalcogen bonding organocatalysis. All the best!

We have now finally completed the renovation of our synthesis labs. Thanks to Ruhr-University Bochum for providing us with such excellent infrastructure!

Thanks to Saber and Richard for the many measurements, to Christoph Held for the very nice cooperation and to our NMR department for their patience!

Halogen Bonding in Solution: Under Pressure The first study of the high-pressure behavior of organic halogen bond donors in solution is presented: HP-NMR titrations were performed in various solvents, primarily with a neutral tridentate halogen...

A paper with a Queen song title? Check! (Even though that was an easy one).
We've investigated the high pressure behavior of halogen bonding and found some unexpected solvent @solvationsci.bsky.social dependence:
pubs.acs.org/doi/10.1021/...

Last monday, we bid farewell to Saber Mehrparvar now that his two-year postdoc stay came to an end. He tackled a difficult project, under high pressure, which will hopefully be published soon. Saber, it was a GREAT pleasure having you around, all the best for your future!

Highly Enantioselective Organocatalysis with Bidentate Halogen Bond Donors In a model Mukaiyama aldol reaction with unbiased substrates, high enantioselectivity was achieved with a modifiable bidentate iodine(I)-based halogen bonding organocatalyst. The crucial role of halo...

Said opus magnum (see below) is now in its final layout: highly enantioselective organocatalysis with bidentate halogen bond donors! A breakthrough that we had been hunting fir many, many years: onlinelibrary.wiley.com/doi/10.1002/...

Congrats - very useful method. And welcome to BlueSky!

Today, Julian Wolf briliantly defended his thesis, congrats! His opus magnum can be found here: chemrxiv.org/engage/chemr.... Thanks to Raphael Stoll for chairing and to Gerald Dyker, Nils Metzler-Nolte for co-reviewing!

Ein Appell von S4F an die Politik

Die Klima­krise und weitere Umweltkrisen (Biodiversitätsverlust, Überlastung biogeochemischer Stoffkreisläu­fe, ...) sind mittelfristig die größte Bedrohung für Sicherheit, Wirtschaft und Wohlstand, Demokratie, Zivilisation und Menschenleben.

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Asymmetric Counteranion-Directed Halogen Bonding Catalysis Halogen bonding has been established as a promising tool in organocatalysis. Asymmetric processes are nevertheless scarce, and their applications are limited to a few studies applying chiral halogen b...

The combined power of halogen bonding and asymmetric counteranion-directed catalysis = XB-ACDC: pubs.acs.org/doi/10.1021/.... Thanks to @mertenlab.bsky.social for structure elucidation and to the List group for this beautiful cooperation! A perfect #RESOLV project! @solvationsci.bsky.social

Ortho‐Carborane‐Derived Halogen Bonding Organocatalysts Multidentate neutral halogen bonding catalysts based on iodinated icosahedral ortho-carborane moieties are introduced. Co-crystallization-studies, calorimetric measurements, and 1H NMR titrations dem...

So far, strong neutral halogen bond donors were often based on fluoroarenes. Here, we present ortho-carborane-based systems that clearly outcompete them: onlinelibrary.wiley.com/doi/10.1002/.... Thanks to Jas Ward and Kari Rissanen for the X-ray analyses and to Sandro Keller for assistance with ITC.

Thanks for the list! Could you please add our group? Thanks!

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After a one-year hiatus on this platform, we have decided to move here for good - it's just a so much nicer place than the other one...

PS: For all biochemists and biologists who have started to follow us: thank you for your interest, but be aware that we don't really work much in these areas...

We all wish you Merry Christmas and a great start into the New Year!

It's nice and concise, just consider it a suggestion for future version v2...

No offense, but by now this is indeed a bit outdated... no halogen bonding, chalcogen bonding, etc. ... ;-)

We wish you - and in particular our three followers - merry Christmas and a great start into the new year!