Radovan Sebesta

Spreading the word that mechanochemistry is great for metal catalyzed cross-couplings and carbonylations at 77. Meeting of chemists in High Tatras

I am proud to present three new doctors from our group: Dr. Henrich Szabados, Dr. Barbora Zahradnikova, and Dr. Klara Stankovianska.
@comeniusuni.bsky.social

Our newest example of catalytic mechanochemistry - atroposelective organocatalytic synthesis of 1,2'-binaphthalene-3'-carbaldehydes under mechanochemical conditions - now published in RSC Mechanochemistry
@comeniusuni.bsky.social, with Henrich Szabados
doi.org/10.1039/D5MR...

I played the Leningrad variation of the Dutch defense.

I always love returning to Switzerland. This time to attend #EuCOMC2025 in Bern and speak about mechanochemical cross-couplings.

Cordial congratulations to our PhD student Zuzana Mravíková for receiving Dean´s award for the best publication of PhD students for her work published in ChemSusChem 2025, 18, e202402599 (lnkd.in/eWDu5ppB)

I cordially welcome our new postdoc, Dr. Suman Yadav, have a good time in research group.

Yes, arrows are a fascinating topic 😃

The thematic issue “Advances in asymmetric #organocatalysis II” ed. by Radovan Šebesta @rsebesta.bsky.social, @comeniusuni.bsky.social, in the Beilstein Journal of Organic Chemistry is complete ➡️ https://tinyurl.com/yc24a85y
#GreenChemistry #greensolvents #catalysis #DiamondOpenAccess 💎🔓 #BJOC

Outstanding peer reviewers | Royal Society of Chemistry Thank you to each and every one of our peer reviewers working tirelessly to ensure that the scientific record is accurate and getting great science into the world.

I am happy to share that I’ve been recognised as one of the Royal Society of Chemistry’s 2024 outstanding reviewers for @chemcomm.rsc.org . Explore the full list at rsc.li/OutstandingReviewers2024 #RSCPeerReview

Mechanochemical Radical Boronation of Aryl Diazonium Salts Promoted by Sodium Chloride Mechanochemically performed boronation of arene diazonium salts is presented. The key feature of this method is NaCl which significantly enhances this procedure. Mechanistic and DFT investigations su...

It is nice to learn that our work is read. Our article received enough views to be a Top Viewed Article. Read it here onlinelibrary.wiley.com/doi/full/10.... #TopViewedArticle
@wiley.com

Our chapter "Partial Reduction of Enones, Styrenes, and Related Systems" for the upcoming release of Comprehensive Organic Synthesis is published
doi.org/10.1016/B978...
With Dr. Viktoria Nemethova, @comeniusuni.bsky.social

Pd‐Catalyzed Cross‐Coupling of Organozinc Pivalates with Arene Thianthrenium Salts under Ball‐milling Conditions Cross-coupling reactions are important tools in the synthesis of complex molecules. Here we show that the Pd-catalyzed cross-coupling of aryl zinc pivalates with aryl thianthrenium salts offers a gre...

Mechanochemistry and organometallics - Pd-catalyzed coupling of organozinc pivalates and arene thianthrenium salts go well together as can be seen in our recent work
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
@comeniusuni.bsky.social, T. Carny, M. Mart, M. Blauciak, B. Steinhublova.

Reunion with past and present group members at the occasion of my 20 years at Comenius University

🧪Here are our current open positions:
www.benferinga.com/vacancies/

- PhD on Functional DNA-Rotator Motors
- PhD in the Origin of Homochirality
- PhD on Expanding Prebiotic Chemistry Through Reactivity in Oil Droplets
- Postdoc Molecular motors based DNA-walkers

📢 PhD position is open in my group starting in october 2025 for 3-years.
MSc. 👨‍🎓 interested in environmental chemistry; it is time to apply for exciting science at #PC2A @univlille.bsky.social @cnrs-hautsdefrance.bsky.social
@ph15.bsky.social @arizonastateuni.bsky.social
deadline: april 25th 2025

Mechanochemical Palladium‐catalyzed Cross‐coupling of Thianthrenium Salts and Arylboronic Acids Cross-coupling reactions are indispensable for the construction of complex molecular scaffolds. In this work, we developed a sustainable methodology for the cross-coupling reaction of arene thianthre...

Another product of our passion for catalytic mechanochemistry - Suzuki-type cross-coupling with thianthrenium salts #ChemSusChem, #Mechanochemistry
doi.org/10.1002/cssc...
@comeniusuni.bsky.social
Zuzana Mravikova, Tibor Penaska, Daniela Horniakova

Recent advances in organocatalytic atroposelective reactions Beilstein Journal of Organic Chemistry

If you are interested in asymmetric organocatalysis and axially chiral compounds, check out our recent review in Beilstein J. Org. Chem. Chem.
www.beilstein-journals.org/bjoc/article...

Utilizing N‐Hydroxylamine‐Based Active Esters for the Synthesis of Oseltamivir Amide Derivatives Hydroxylamine-derived active esters were synthesized from oseltamivir, which can serve as practical synthetic handles to prepare oseltamivir analogs. Succinimide-based active ester was the most effec...

If you are interested in how to make carboxamide derivatives of oseltamivir, check out our recent article in EurJOC chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

Mechanochemical Pd‐Catalyzed Cross‐Coupling of In‐Situ Generated Reformatsky Zn‐Enolates Transition-metal-catalyzed α-arylations of carbonyl compounds have shown to be a useful strategy for the late-stage synthesis of α-arylesters. However, the use of strong basic conditions and difficul...

I present our newest work on mechanochemical cross-couplings of Reformatsky enolates with aryl halides, which has been published in Advanced Synthesis and Catalysis onlinelibrary.wiley.com/doi/10.1002/...

Our new toy for mechanochemistry! We believe chemical reactions should be shaken, not stirred. :D