Kevin Frank, MD

It has taken medical science 200 years to advance humans to the point where people are so healthy and living so long that they can deny that science and medicine is what got us here.

DOI: 10.1016/j.chest.2024.06.1618, pmids 38465145 and 37265888. Hope it helps!

Some case reports of methylene blue plus hydroxycobalamin are promising. But yes.

I feel like 2025 is more IVC plus VeXUS plus lung u/s plus echo (vti and E/e’ as a surrogate for wedge, specifically). But I’m a fancy boi, so.

Wow! France gifted her to us, and now they’ve captured what so many Americans are feeling on Independence Day. The values the Statue of Liberty stood for are no more.

📌 A stunning mural of the Statue of Liberty covering her face was unveiled in Roubaix, France, on July 3, 2025.

With hazard ratios like this, it’s pretty obvious the study was underpowered. Curious why the authors didn’t try to amend it for additional patients after an interim analysis.

ZODIAC trial: For ischemic stroke patients who are awaiting thrombectomy, flat positioning reduced the risk of neuroworsening or death

Premature termination but seems reasonable

Statistically robust results

Best available evidence; should change practice

pubmed.ncbi.nlm.nih.gov/40465238/ #EMIMCC

old drugs in HT

Plenary at @hypertensioncanada.bsky.social with @drjmluther.bsky.social on new drugs

He starts of with the really old drugs!

#CHC25

When they accidentally tell the truth... (Pt. 2)

(also try to avoid swimming in sewage)

Antimicrobial Chemotherapy for Legionnaires' Disease: A Review Abstract. Controlled trials of antimicrobialchemotherapy for legionnaires' diseasehave not been performed, although erythromycin and tetracycline appear to

Seems like a lot of the references come back to Edelstein’s 1995 article from Clinical Infectious Diseases.

Sanford guide agrees (and Hopkins abx).

Harvard has set an example for other higher-ed institutions - rejecting an unlawful and ham-handed attempt to stifle academic freedom, while taking steps to make sure students can benefit from an environment of intellectual inquiry, rigorous debate and mutual respect. Let’s hope others follow suit.

I may be tired and a little hoarse, but as I said again and again on the Senate floor, this is a moment where we cannot afford to be silent, when we must speak up.

what’s not to love about HIGH-INTENSITY bipap? 😂 💪 #EMIMCC

2025 ILCOR CoSTR
1/14 🧵 Just released! The 2025 @ILCOR_org Consensus on Science With Treatment Recommendations (CoSTR) brings major updates to #resuscitation guidelines. Let's break down the key changes across all task forces! #CPR #ECC #FOAMed #Emedsky #medsky #emimcc #emergencymedicine

Especially for LV function in critical illness, MAPSE rocks.

Obituary: Luciano Gattinoni - ESICM In Memory of Professor Luciano Gattinoni

A sad day for critical care - and what a phenomenal legacy he has left us.

RIP Prof Gattinoni, a Giant ⚕️📟

www.esicm.org/obituary-luc...

When interpreting this trial, it is also important to consider the pre-specified adjusted analysis [OR 0.89 (95%CI 0.79 to 0.99)] as adjustment improves statistical efficiency. This article explains the benefits of adjustment quite well. #emimcc jamanetwork.com/journals/jam...

If the LV of the patient with sepsis is «hyperdynamic» when on noradrenaline, then EF dropps and the LV looks poorly when vasopressin is added, but recovers to normal with dobutamine, you likely haven’t «uncovered hidden LV dysfunction» or septic cardiomyopathy. #emimcc #pocus #echofirst 1/

Bubble chart showing the ethnic makeup of Queens, NYC in 2021z

Diversity is strength, and it is joy. #IDIC IYKYK

Facts matter. Science saves lives. Anti-science destroys them.

Long COVID: a clinical update Post-COVID-19 condition (also known as long COVID) is generally defined as symptoms persisting for 3 months or more after acute COVID-19. Long COVID can affect multiple organ systems and lead to sever...

Reproducing my thread from the Other Place on our Lancet paper 'Long COVID - a clinical update'. Coauthors Manoj Sivan, Alice Perlowski, Janko Nikolich. 1/

www.thelancet.com/journals/lan...?

Check out the CCT infographic on ICU delirium:
🥴 causes
😴 prevention
💊 treatment

Listen to our podcast with @weselymd.bsky.social:
Apple podcasts.apple.com/us/podcast/c...
Spotify open.spotify.com/episode/6fKD...
YouTube youtu.be/hp9baJl51lQ?...

Shownotes www.criticalcaretime.com/episodes/del...

Reposting an old thread on the history of MAPSE! The first to recognise long axis movement as the primary movement of the heart was none other than da Vinci! #echosky #pocus #medsky # #cardiosky www.onlinejase.com/article/S089...

Great pack!

Would appreciate being added!

Correction Rates and Clinical Outcomes in Hospitalized Adults With Severe Hyponatremia This systematic review and meta-analysis evaluates the association of sodium correction rates with mortality among hospitalized adults with severe hyponatremia.

Honey, stop what you're doing, new hyponatremia research just dropped!

What's it say?

It looks like slow correction is associated with worse outcomes, like death and length of stay!

Was it just a small study?

No, it was a meta-analysis of almost 12,000 patients!

jamanetwork.com/journals/jam...

#VEXUS cheat sheet by Sonosite

VEXUS is mainstream...

#EMIMCC #POCUS