Nadja Ging Jehli

From symptom-based heterogeneity to mechanism-based profiling in youth ADHD: the promise of computational psychiatry - Neuropsychopharmacology Neuropsychopharmacology - From symptom-based heterogeneity to mechanism-based profiling in youth ADHD: the promise of computational psychiatry

#ThisWeekInNPP

This 🔃 Review🔃 discusses how computational psychiatry can reveal latent mechanisms in ADHD & mood disorders, emphasizing ways to ⬆️ reliability & develop more precise, ecologically valid models for diagnosis & treatment / @nadjagingjehli.bsky.social

www.nature.com/articles/s41...

Keynote by Dr. Ging-Jehli on Adaptability in the Digital Age: From Neuroscience to Next-Generation Agentic AI and Health Ecosystems, 7 October 2025 Tuesday, 07 October 2025,  4.15 pm CET, Hybrid: HSG–ITEM A 24-0-216 or ZOOM  About Nadja Ging-Jehli Dr. Nadja Ging-Jehli is a neuroscientist and economist studying how people and machines adapt in u...

Excited to keynote the HSG Digital Health Forum next week! 🚀
Topic: how our brains adapt to change and how neuroscience × economics × agentic AI can drive adaptive digital health for ADHD, anxiety & depression.
📅 Oct 7, 16:15 CET
👇 Join us: www.c4dhi.org/news/251007-...

From symptom-based heterogeneity to mechanism-based profiling in youth ADHD: the promise of computational psychiatry - Neuropsychopharmacology Neuropsychopharmacology - From symptom-based heterogeneity to mechanism-based profiling in youth ADHD: the promise of computational psychiatry

Our #ComputationalPsychiatry review paper is published in #Neuropsychopharmacology! 🎉
We outline how to move beyond single constructs, and what’s needed for real clinical impact, with ADHD as a key case example. Toward adaptive, precision psychiatry👉 www.nature.com/articles/s41...

Heading to #AIplusX2025 in Zurich! 🚀
My focus: agentic AI × neuroscience x mental health.
I’m building Gearshift Fellowship: an adaptive game platform to study adaptability + digital mental health. Who else is exploring this space? Let’s connect!
#AgenticAI #AIforHealth #Neuro #AIXSUMMIT

A Novel Approach-Avoidance Task to Study Decision Making Under Outcome Uncertainty To behave adaptively, people need to integrate information about probabilistic outcomes and balance drives to approach positive outcomes and avoid negative outcomes. However, questions remain about ho...

Our newest preprint “A novel approach-avoidance task to study decision making under outcome uncertainty” investigates the dynamics of approach-avoid decisions!

Check out www.biorxiv.org/cgi/content/..., led by Ziwei Cheng and @nadjagingjehli.bsky.social

Honored to receive a Travel Award from #CPConf2025 😇 Presented on ADHD-specific adaptive mechanisms in social strategic interactions - underexplored aspects of clinical significance!
🔥 Inspired our #GearshiftFellowship platform 🧠🎮 Link: osf.io/preprints/ps...

… or a task battery. it’s a structured, scalable environment to study how minds and machines adapt across changing goals, uncertainty, and social cues. First validation studies + human-AI experiments coming soon. Stay tuned! 🥳🤩

🚀 Our GearshiftFellowship method paper introducing “Supertask” has been accepted in Springer LNCS!
We propose a reconfigurable game environment to study adaptability in humans & AI. 🌍🧠
Preprint: osf.io/preprints/ps...

#NeuroAI #MetaLearning

Supertask isn’t just a game…

🥳 Honored to join the ACNP community as an Awardee! ✨ Excited to step into this exceptional space where neuroscience, AI, and psychiatry meet to advance how we understand and care for mental health. Toward an integrative ecosystem. #ACNP2026 #GearshiftFellowship #AdaptiveMinds

At #RLDM2025 presenting Gearshift Fellowship: a reconfigurable platform to study how humans & AI agents co-adapt under shifting uncertainty, effort & control. More than a framework - it’s a testable ecosystem. Let’s connect. 🔁🤖🧠
#AI #MetaLearning #CompPsych #SeriousGames

I am hiring for RA, PhD, and postdoc positions. Come work with me on how we use simplified models of the world to plan in complex environments!

University of Arizona is located in Tucson with incredible access to the outdoors.

If you are interested, reach out to me! (2/2)

How do we decide when to switch gears - when surrounded by uncertainty and control loss?
🧠Calling scientists in cog modeling & AI: Let’s connect at #RLDM2025 if you are working on adaptive agents, meta-learning. Towards adaptive co-evolving human-AI systems: www.gingjehli.com/gearshiftfel...

2/2 A next-gen ecosystem bridging neuroscience, AI, behavior and clinical insights - not just for psychiatry but for how we understand adaptable minds! 🧠💡🔬 An early glimpse into what I’ve been building and my vision: www.gingjehli.com/gearshiftfel...

The future of brain and mental health research won’t come from static tasks or narrow models. It’ll be built through adaptive systems - ones that learn, reason, and scale with us. That’s what I’m building with Gearshift Fellowship 👇 1/2

Excited to share our upcoming workshop on neuroscience, reinforcement learning, and decision making at RLDM 2025 in Dublin, Ireland — June 11–14!

Check out the terrific speaker lineup:

🔗 sites.google.com/view/neurorl...

Co-organized with @angelaradulescu.bsky.social

@rldmdublin2025.bsky.social

📢 #RLDM2025 is nearly here – 11–14 June at Trinity College Dublin ☘️

Join researchers from AI, neuroscience, psychology & beyond to explore the latest in reinforcement learning & decision making.

🎟️ Register now to secure your spot: rldm.org #ReinforcementLearning #AI #Neuroscience #CognitiveScience

Our work from a great collaboration now out at Brain Stimulation: doi.org/10.1016/j.br...

We find that 4 Hz STN stimulation in *humans* changes decision thresholds:

Data: narayanan.lab.uiowa.edu and osf.io/hsz3u
With Rachel Cole and Jim Cavanagh

Are you planning to attend @rldmdublin2025.bsky.social #RLDM2025 and interested in human and artificial intelligence across the adult lifespan? Come check out our Representational Alignment and Aging Workshop!👇
sites.google.com/brown.edu/raa/

Theta-frequency subthalamic nucleus stimulation increases decision threshold Executive functions are often impaired in patients with Parkinson’s disease (PD), and these deficits can be predicted by decreased frontal cortical 4-…

Excited to share our new paper: whether STN stimulation increases impulsivity depends on theta frequency. 🧠🤓 Grateful to have contributed alongside such a fantastic team! Rachel, Kumar,
@jimfcav.bsky.social @janw.bsky.social and more! Link 👇: www.sciencedirect.com/science/arti...

Absolutely! 😃

Computational Psychiatry Conference Tübingen, Germany (July 14-16, 2025)

📢 Early registration prices end tomorrow 15 April! 🚨

Computational Psychiatry Conference is 14-16 July in Tübingen, Germany. www.cpconf.org

Speakers inc. Phil Corlett, Charlotte Fraza, Andreas Heinz, Georgia Koppe, Jill O'Reilly, Chandra Sripada, Sophie Valk, Tor Wager

Life update 🚨🧵 This job market season I got close, but no spaghetti 🍝, to landing an assistant professor job. I put in 52 customized applications, expending a level of effort on par w grad school qualifying exams & dissertation defense 😅. I gave it my all at campus interviews, & enjoyed meeting many

a red neon sign that says help wanted on a black background . ALT: a red neon sign that says help wanted on a black background .

ATTENTION: TALENT AVAILABLE

It appears that termination of SROs from institute review branches at NIH is underway (or worse).

There are also program officers and SROs who have been terminated over the past month.

IF YOU HAVE POSITIONS FOR SKILLED SCIENTIST-ADMINISTRATORS, PLEASE POST INFO HERE

🍂 List of rescinded NIH Grants
🧪
Add terminated awards to list

I’m an NIH-funded researcher, drowning in uncertainty “I’ll keep doing what I can to move my research forward. But I, and so many others, can’t do this indefinitely,” this assistant professor writes

The devastating uncertainty caused in researchers by the NIH funding cuts/policy changes www.science.org/content/arti...

Book cover: orange yellow background, and generated tree in front

If you would like to teach theoretical modeling skills to your psychology or cognitive science students, or would like to learn these skills yourself, check out our open online textbook: computationalcognitivescience.github.io/lovelace/

Upon learning that yesterday would be my last day as a program officer at the National Science Foundation, I shared this parting message with my colleagues. The next few months will be frenetic and stressful for them. Here are some things that you can do to help them with the mission ahead. (1)

🥳thrilled that our dockerHDDM tutorial paper, after many years's work was published in my dream journal AMPPS of @psychscience.bsky.social 🤩
👇
doi.org/10.1177/2515....

The image's been downloaded 10K+⏬ docker Hub

Such a pleasure to work w/ Wanke, Ru Yuan, Haiyang & member of HDDM/HSSM team!

In case you were worried about PubMed disappearing

Task-evoked neuronal response. Left: Stimulus-induced mean changes (solid/dotted bold lines) in theta power (4–8 Hz) by condition. Right: Time frequency plots show a task-evoked increase in LFO power (averaged across channels) relative to baseline. Spectra are shown for high minus low conflict (averaged across coherence) aligned to stimulus onset (left panel) and response (right panel) for each basal ganglion component (STN – subthalamic nucleus; GPe – globus pallidus externus; GPi – globus pallidus internus).

#BasalGanglia are critical for decision-making, but how are their subregions coordinated? @nadjagingjehli.bsky.social &co show how the different subregions regulate #decision dynamics under varying degrees of conflict & uncertainty in a perceptual decision task 🧪 @plosbiology.org plos.io/3WC13cq