Spyros Lytras

Interesting interview of @peterdaszak.bsky.social by @nicolascgrey.bsky.social on the personal consequences of having become a public villain in a set of conspiracy theories

www.thisrobotdreaming.com/blog/intervi...

🚨 New Web Resource Alert! 🚨 We're delighted to share Viro3D a database of >85000 viral protein structure predictions from >4400 human & animal viruses.

🔗 viro3d.cvr.gla.ac.uk
📄 www.embopress.org/doi/full/10....

@molsystbiol.org @cvrinfo.bsky.social @uofgmvls.bsky.social #Virology #AlphaFold 🧪 🦠

Viro3D: a comprehensive database of virus protein structure predictions | Molecular Systems Biology imageimageViro3D provides proteome-level, high confidence AI-protein structure predictions for >4,400 viruses, allowing mapping of form and function across the human and animal virosphere. Viro3D i...

Viro3D paper is out! We predicted 85,000 protein structures from human & animal viruses. 1/5 🧵

📑 Paper doi.org/10.1038/s443...
🔭 Explore virosphere viro3d.cvr.gla.ac.uk

The Viro3D database includes:

✅protein structures across the human and animal virosphere
✅comparative analysis between structures
✅interactive web interface
✅taxonomic indexing

We hope that this turns into a useful resource for all kinds of virologists!

Browse here: viro3d.cvr.gla.ac.uk

Viro3D: a comprehensive database of virus protein structure predictions | Molecular Systems Biology imageimageViro3D provides proteome-level, high confidence AI-protein structure predictions for >4,400 viruses, allowing mapping of form and function across the human and animal virosphere. Viro3D i...

New exciting resource published!! The Viro3D paper is out, describing our comprehensive database of predicted virus protein structures! 💻🧬

Work with @ulad-litvin.bsky.social , @grovearmada.bsky.social , Alex Jack, @bljog.bsky.social , @davidlrobertson.bsky.social

www.embopress.org/doi/full/10....

#RECOMB2026 will be in Thessaloniki, Greece on May 26-29, 2026. Satellites on May 24-25. Save the date!

Το συνέδριο #RECOMB2026 θα πραγματοποιηθεί στη Θεσσαλονίκη, στις 26-29 Μαΐου 2026. Οι δορυφορικές εκδηλώσεις θα διεξαχθούν στις 24-25 Μαΐου 2026. Σημειώστε την ημερομηνία!

My understanding is that the situation for H1B visa holders outside the US today is urgent: if a current H-1B holder seeks entry into the U.S. after 12:01 a.m. EDT on September 21, 2025, it is too late to avoid the fee—entry will be restricted without the newly-imposed $100,000 employer payment.

New Paper Identifies Widespread Risk Of Coronavirus Spillover In Pigs And People Across Southeast Asia And China - Nature.Health.Global A new scientific paper from Nature Health Global scientists identifies widespread spillover risk of a group of coronaviruses in China and Southeast Asia.

New paper from @naturehealthglobal.bsky.social scientists identifies extensive spillover risk of an under-researched group of coronaviruses in China and Southeast Asia. 🧵
naturehealthglobal.org/new-paper-id...

Arrived in gorgeous cote d' azur just in time for the first day on the European Meeting on Viral Zoonoses!

Aside from enjoying the weather and the wine I'll also be presenting some exciting (and still unpublished) work on novel sarbecovirus discovery! 🍷🏖️🦇

Molecular basis of sarbecovirus evolution and receptor tropism in natural hosts, potential intermediate hosts, and humans Kosugi et al. elucidate sarbecovirus evolution and ACE2 receptor tropism in natural hosts (12 Rhinolophus bat species), potential intermediate hosts (civets and raccoon dogs), and humans using a pseud...

Great to have this one published @cp-cellreports.bsky.social !! Some sarbecoviruses can use more ACE2 orthologs than others. The reason? A few sites in the RBD modulating the receptor usage of these viruses throughout their evolution! Worth a read 👇👇👇

www.cell.com/cell-reports...

Dr. @angierasmussen.bsky.social breaking down current policies and the anti-vaccine trends/rhetoric within the US that will lead to significant global health ramifications - #19vaccinecongress

A bunch of awesome looking vaccinologists standing on a balcony in Kyoto with a backdrop of forested hills

At Vaccine, our editorial team is united to defend and support immunization and vaccine science around the world. I am so proud & honored to stand alongside these outstanding scientists & clinicians to prevent disease & save lives with integrity & courage.

Great to be at Elsevier's 19th Vaccine Congress in beautiful Kyoto! 💉💉

An exceptionally important topic to global health, especially in the current political climate...

Graph showing wildfire carbon emissions in Spain. This year's fires are in a league of their own.

This summer's raging wildfires in Spain are the red spike in this graph. atmosphere.copernicus.eu/copernicus-i...

When Dissent Becomes Domestic Terrorism The call is coming from inside HHS

The shooting at CDC was domestic terrorism. It was instigated by the HHS Secretary's years-long campaign against an agency he oversees.
open.substack.com/pub/rasmusse...

Fantastic work George et al!!!!

GitHub - gbouras13/colabfoldv: Augmented Local MSA Generation for Phage and Viral Proteins using the ColabFold Framework Augmented Local MSA Generation for Phage and Viral Proteins using the ColabFold Framework - gbouras13/colabfoldv

I also put together an extra ColabFold formatted database of nearly 130M phage proteins that can be used to make better viral protein structure predictions github.com/gbouras13/co...

c) With Phold we released more than 3M phage protein structure predictions (see the preprint for bulk download links), including a ColabFold generated proteome for each unique genus in INPHARED. We will make these more user-friendly soon.

For now see linsalrob.github.io/PHROG_struct...

In the arms race between viruses and their hosts, viruses have found a dependable ally..

Integrative modeling of seasonal influenza evolution via AI-powered antigenic cartography Seasonal influenza viruses evade host immunity through rapid antigenic evolution. Antigenicity is assessed by serological assays and typically visualized as antigenic maps, which represent antigenic d...

Check out our latest preprint led by Jumpei Ito and @shusukekawakubo.bsky.social !!

PLANT 🌱 a protein language model for predicting antigenic cartography!

PLANT takes HAs and predicts antigenic map coordinates, allowing for a deep dive into flu antigenic evolution!

www.biorxiv.org/content/10.1...

They are really destroying all research on infectious diseases.

If you're in Oxford tomorrow 👀👀

Some very inspiring science at #ismb2025 in Liverpool this week! And great to see lots of Glasgow friends! 😁

Unfortunately had to dip early to get to Oxford! Giving a talk on structural phylo and discussing some exciting projects with @mghafari.bsky.social tomorrow!👀👀

Today at 5pm, @eunbelivable.bsky.social will present her work on the Big Fantastic Viral Database (BFVD) at #ISMB2025 in BOSC. She also has a poster B-123 (tomorrow, 22nd), so please drop by to have ta chat and grab some stickers!
📄 academic.oup.com/nar/article/...

We look forward seeing you Aug. 12 for our next webinar on Vector-Borne and Zoonotic Diseases. Dr Maringer @maringerlab.bsky.social will present "Virus-specific innate immune responses in Aedes aegypti". Register: lnkd.in/gJdiYGm7. @astmh.bsky.social @sbvirologia.bsky.social @utmbhealth.bsky.social

Protein structure competition, of AlphaFold fame, nearing deal to replace lost NIH funding CASP, a popular research competition that spawned three Nobel laureates, is set to lose NIH funding.

If CASP falls apart, the U.S. would lose its leadership in this area. Without U.S. federal funding, a European or Chinese organization would likely pick up the reins in some way, cofounder John Moult, tells STAT's @brittanytrang.com

www.statnews.com/2025/07/16/c... via @statnews.com

We made structural predictions of representatives of each #PHROG from #phage genomes, and put the whole lot online. You can browse through montages or go to your favourite phrog directly and download its PDB.

💻🧬 #phagesky

linsalrob.github.io/PHROG_struct...

The people in power who are obliterating science are working out of McCarthy’s playbook:

-Don’t attack vaccines or research directly
-Attack the scientists doing the work indirectly
-Imply they are untrustworthy or conflicted
-Accuse them of perpetrating what they are actually the targets of

They've got windows arm laptops now too! Very glad for my little dell's 20hour battery life!! 💻💻💻

Unicore is now published on GBE 🚀
Unicore rapidly identifies structural single-copy core genes from input species proteomes for phylogenetic analysis. Powered by Foldseek and ProstT5, Unicore enables linear-scale structure-based phylogeny of any given set of taxa. 🧵1/n
📃 doi.org/10.1093/gbe/evaf109