The first patients were enrolled into a clinical trial of alpelisib in Dent disease 2 at Bambino Gesù Hospital, funded by Lowe Syndrome, Trust UK and Association USA, and Dent Disease Foundation. The drug was identified by the Gallop and Devuyst labs. Read more: www.bioc.cam.ac.uk/news/first-p...

We're loving hosting students for the @gurdoninstitute.bsky.social ASTP programme, along with @mrc-mbu.bsky.social . As ever, so impressed with the next generation of scientists!

We had a such a great week with this lovely group of students on @gurdoninstitute.bsky.social ASTP programme- they did some fantastic presentations on Friday! Well done to all of them 👋👋👋

Check out this list of posts on @prelights.bsky.social, discussing #preprints in #DevBio and #StemCell biology.

Featured #preLight is by Jethro Lundie-Brown @scicambridge.bsky.social on a preprint by @sumrubayin.bsky.social & co.

journals.biologists.com/dev/article/...

🌟Congratulations to Azim Surani @gurdoninstitute.bsky.social @cam.ac.uk for receiving the 2025 Kyoto Prize - Basic Sciences. Azim's research fundamentally advanced our understanding of developmental biology🔬🧬 www.gurdon.cam.ac.uk/kyoto-prize-...
#KyotoPrize #AzimSurani #DevelopmentalBiology

🎉 Congratulations to the Rawlins Lab on receiving an ERC Advanced Grant for their LungDeCode project! 🫁🔬The project lays the foundation for future human lung regeneration.
#ERCGrant #GurdonInstitute #SBS_Cambridge

CRAMP1 drives linker histone expression to enable Polycomb repression In contrast to the well-understood role of core histones in DNA packaging, the function of the linker histone (H1) remains enigmatic. Challenging the …

🆕 New publication from the Tchasovnikarova Lab!
CRAMP1 drives linker histone expression to enable Polycomb repression 🧬
Read the full study in Molecular Cell:
🔗 sciencedirect.com/science/arti...

#Epigenetics #Chromatin #GeneRegulation #Polycomb #GurdonInstitute #SBS_Cambridge

Carmina Santa-Cruz Mateos from PDN, University of Cambridge: "Condensing the Message: How Notch Signaling Forms Transcriptional Hubs to Control Gene Activation" Jimena Berni from Medical Research Building, University of Sussex – “Hox Activity Levels Govern the Evolution of Behaviors” Expect refreshments and pizza, this is a great chance to meet colleagues, exchange ideas, and build collaborations. Spread the word, everyone is welcome!

🗓️#CambridgeFlyClub 2nd meeting this year on July 16th (Weds) 4pm at @gurdoninstitute.bsky.social. Our speakers are Carmina Santa-Cruz Mateos from Sarah Bray's lab @pdncambridge.bsky.social and Jimena Berni from University of Sussex.
It's not the Dmel on our poster, guess what species is it?

Welcome 2025 Fellows and congratulations to all! Excited to see our @geraldinejowett.bsky.social in the list! @gurdoninstitute.bsky.social

Amazing to host Jen Sucre to give a talk @gurdoninstitute.bsky.social yesterday. Fun times and the most beautiful lung images. Plus a relaxing evening with the whole lab - thanks all! Warm June evening in Cambridge - Pimms was required!

A beautiful day to celebrate #CambridgePride with the Old Addenbrooke’s Neighbourhood @phar.cam.ac.uk @mrc-tu.bsky.social @cambiochem.bsky.social @gurdoninstitute.bsky.social 🏳️‍🌈

Frontiers | Lowe Syndrome and Me: a co-creation video series connecting patients, caregivers, and researchers Lowe syndrome (LS) is a rare genetic disorder leading to significant physical and cognitive impairments. Recognizing the need to bridge the gap between resea...

The Gurdon Institute Public Engagement team, Lowe Syndrome Association patient charity and Gallop laboratory have written an article about their co-production collaboration for the 2024 International Lowe Syndrome Symposium www.frontiersin.org/journals/cel...

May is Lyme Disease Awareness Month
Lyme disease is a bacterial infection transmitted through the bite of an infected tick. If caught early, antibiotic treatment is usually effective but treatment delay can lead to long term debilitating symptoms. Prevention is better than cure, please read here!

Photo of seminar with headshot of Sumru Bayin and title of her talk

Today we welcomed Dr Sumru Bayin for our Group Leader Seminar! Dr Bayin is CSCI's Affiliate PI, and Group Leader at @gurdoninstitute.bsky.social. She was hosted by @bertiegottgens.bsky.social and presented on 'Age-dependent regenerative mechanisms in the brain.' Thanks to all who joined!

We are looking forward to @schierlab.bsky.social talk tomorrow at 11 AM in our Tea Room

We're looking forward to host Professor Merixtell Huch back @gurdoninstitute.bsky.social on Tuesday, 29 April at 11AM.

My lab decided to celebrate international women's day this year - though women in STEM is clearly every day 😀

Graphic containing the Cambridge Festival pink logo and four Fast Facts on Lyme disease. It is caused by bacteria Borrelia - the bacteria can be passed to human through the bite of an infected tick. It can cause a distinctive rash called an EM rash, but not everyone with the disease will have one. Not all ticks are the same - there are around 20 different species of tick in the UK. Bites can be missed by patients - nymph ticks (the immature stage) can be as small as a poppy seed.

If you are in or around Cambridge UK, join us at the @cambridgefestival.bsky.social family weekend on 29th and 30th March. Stop by my stand and learn some tick bite prevention techniques in #TickBitePreventionWeek. Sharing resources from @lymeresourcecentre.bsky.social @lymediseaseuk.bsky.social

Starting the new year with the last chapter of my PhD finally published on how physical forces and neighbour interaction regulate extrusion in @bladoux.bsky.social @rmmege.bsky.social in collaboration with Doostmohammadi group. Details below:https://www.nature.com/articles/s41567-024-02716-5

It was a lovely event - thanks for organising @gurdoninstitute.bsky.social public engagement team! Great that 2 lab members could showcase their work also.

We had an excellent time yesterday welcoming science enthusiasts to @gurdoninstitute.bsky.social and sharing our research as part of @camfest1.bsky.social
@cambridgebiosci.bsky.social 🧠

Thank you everyone for joining us in person or online.

Congratulations to Mien Chew (Rawlins Lab) who won 1st prize and Ana Hernandez Rodriguez (Xiong Lab) who won runner up for the PhD poster presentations at the Biologist100 conference 🧬
Thank you to the organisers: biologist.bsky.social and bsdb.bsky.social

The emergence of human primordial germ cell–like cells in stem cell–derived gastruloids 3D human gastruloids mimic gastrulation and postgastrulation development, forming the three germ layer derivatives and hPGCLCs.

Enjoy a facinating new publication from the Surani lab here at the Gurdon Institute 🗞️

It explores "The emergence of human primordial germ cell-like cells in 3D gastruloids".

Read the full article here: www.science.org/doi/10.1126/...

#DevBio #research #science #GurdonInstitute

Join us on Monday, 17 March at 4pm for drinks and nibbles and meet Prof. Christine Holt, Professor Emerita of Developmental Neuroscience. Christine will share with us her journey and the challenges she faced. This event will kick off the Couch Talks, an initiative organized by the WIDE Committee.

It was great to be back @cambridgeuni.bsky.social to give a talk @gurdoninstitute.bsky.social Developmental Biology Seminar Series, and to talk science with people from @scicambridge.bsky.social, @loke-ctr.bsky.social, and @mrclmb.bsky.social!

Spring has sprung @christscollegecam.bsky.social!

@gurdoninstitute.bsky.social We celebrate the contributions of women in science and beyond. We recognise women who inspire, lead and push the boundaries of discovery every day.
Together we work towards a future where science thrives through diversity, inclusion and equality.

#InternationalWomensDay

Should be fun events @gurdoninstitute.bsky.social

Cambridge Festival 2025 - 25 March 6pm
Join Prof. Emma Rawlins 👩🏻‍🔬🫁 @gurdoninstitute.bsky.social
and her team 👩🏻‍🔬👨🏼‍🔬 for an evening of drinks 🍷🍻🍕 nibbles, discussion and discovery 🔬🧪. Come for the science, stay for the conversation 🙋🏼‍♀️🙋🏻🙋🏽‍♂️—don’t miss out on this exciting event!

📢 We are delighted to host
@mhaniffa.bsky.social on Thursday for our Gurdon Institute Seminar Series, hosted by Emma Rawlins and @sumrubayin.bsky.social

All welcome 😀
🗓️ Thursday, 20 February 2025 at 11 am
🎙️ The tapestry of human prenatal immunity
📍Gurdon Institute, Tennis Court Road CB2 1QN