From Venoms to Vanity: Exploring Animal Toxins as Cosmeceuticals - PubMed The integration of biologically active compounds into cosmetics has led to the emergence of cosmeceuticals, bridging the gap between traditional skincare and pharmaceutical applications. While animal ...

Interesting review of animal toxins as cosmetic supplements (Botulinum toxin being a prime example): pubmed.ncbi.nlm.nih.gov/40759186/

The transcriptome of the olm provides insights into its evolution and gene expression - PubMed The olm (Proteus anguinus), with a predicted maximum lifespan of more than 100 years, is the longest-lived amphibian, which in addition possesses a range of unique adaptations to its dark, subterranea...

A new study on one of my favorite animals- the olm (the oldest living amphibian 100+ years)!
pubmed.ncbi.nlm.nih.gov/40754627/

Moderate coffee and tea consumption is associated with slower cognitive decline - PubMed BackgroundGlobally, coffee and tea are consumed extensively, potentially providing neuroprotection through anti-inflammatory and antioxidative stress effects.ObjectiveThis study aimed to investigate a...

Maybe evening the negative paper about coffee yesterday, here's yet another study showing coffee/tea is good for your brain. pubmed.ncbi.nlm.nih.gov/40686251/

Plant-based diet and risk of arthritis: a nationwide cohort study of the Chinese elderly population - PubMed <span><i>Background</i>. This study was aimed at investigating the association between a plant-based diet and the risk of arthritis and at identifying a strategy that achieves the ambitious goal of he...

A plant-based diet may help decrease arthritis: pubmed.ncbi.nlm.nih.gov/40704423/

Epidemiology of pickleball injuries by age group treated in emergency departments in the United States - PubMed Distinct injury patterns between younger and older players suggest the need for age-specific prevention strategies. Older players face higher fracture risks, while younger players are more prone to st...

Pickleball- it's a danger to older people (65+) :p
pubmed.ncbi.nlm.nih.gov/40704451/

Association Between Low Calf Circumference and Incident Sarcopenia in Community-Dwelling Older Adults: A 3-Year Prospective Cohort Study Calf circumference (CC) is a widely acknowledged indicator of skeletal muscle mass within the current consensus among experts. Nevertheless, the relationship between low calf circumference and new-ons...

If you're going to work out some muscles, make sure its your calves :) I think forearms and calves are the muscle groups best correlated with other beneficial effects (can't remember ever seeing any other muscles mentioned for some reason).

www.jamda.com/article/S152...

Retraction of Controversial Arsenic-Life Paper Stirs Debate Among Scientists Science retracted a 2010 study that claimed bacteria could use arsenic for growth. Some scientists support the decision, while others find it harsh.

There are many papers from the past that turn out to be incorrect about their conclusions or over enthusiastic in their interpretation of the data. Science is self-correcting. It is a mistake to retract this paper as their was no scientific misconduct involved.
www.the-scientist.com/retraction-o...

Coffee consumption as a double-edged sword for serum lipid profile: findings from NHANES 2005-2020 - PubMed Coffee consumption exerts both beneficial and adverse effects on serum lipid profile. While it is positively associated with elevated TC and LDL-C levels, its relationships with HDL-C and TG are more ...

I guess it was inevitable but here's some data showing the negative effects of coffee: pubmed.ncbi.nlm.nih.gov/40704303/

Sequencing | Test 100% Of Your Genes | DNA Kits + Reports Everything you need to transform your DNA into clear solutions for better health. Whole genome sequencing (WGS) kits + DNA Reports + Privacy Forever protection.

Wow, only $379 for whole genome sequencing (WGS) now (in my head I thought WGS was still $1,00)? Sale going on at sequencing.com. 30x coverage too. I'm getting myself sequenced :)

Sedentary behavior accelerates biological aging mediated by body mass index in adults - PubMed Sedentary behavior is widely recognized as a detriment to health. Limited conclusions have been drawn about the relationship between sitting time and biomarkers-measured aging. 12,504 eligible adults ...

Fat is old?

pubmed.ncbi.nlm.nih.gov/40594876/

Exploring the impact of coffee consumption and caffeine intake on cognitive performance in older adults: a comprehensive analysis using NHANES data and gene correlation analysis - PubMed Not applicable.

Another study finding a positive correlation between caffeine intake and better cognitive outcomes in older people.
pubmed.ncbi.nlm.nih.gov/40597402/

Staying in unhappy marriages and mental health of children and adolescents: A large-scale cross-sectional study in China - PubMed Public awareness should be raised that divorce may not be the worst option when parents are in an unhappy relationship, at least when considering the potential association with their child and adolesc...

New study from China suggests that staying in an unhappy marriage "for the children" may not actually be a good idea:

pubmed.ncbi.nlm.nih.gov/40555348/

This is the first ever confirmed skull of a Denisovan Finally, we can put a face on a Denisovan.

The first skull of a Denisovan has been positively identified: www.nationalgeographic.com/history/arti...

Coffee Consumption Is Associated With Later Age-at-Onset of Parkinson's Disease - PubMed Observation studies suggest that coffee consumption may lower the risk and delay the age-at-onset (AAO) of Parkinson's disease (PD). The aim of this study was to explore the causal relationship and ge...

More benefits of coffee? This time it may delay the age of onset of Parkinson's disease.

pubmed.ncbi.nlm.nih.gov/40503905/

Suicidal hanging with complete decapitation: A forensic case report with review of biomechanics - PubMed Decapitation resulting from hanging is an infrequent phenomenon, often influenced by multiple biomechanical factors. We report a case of a 72-year-old male who committed suicide by hanging, leading to...

Not exactly sure why this popped up in my pubmed feed but ☠️🤮 pubmed.ncbi.nlm.nih.gov/40479918/

Kennedy Removes All C.D.C. Vaccine Panel Experts

What?!? Kennedy Removes All C.D.C. Vaccine Panel Experts www.nytimes.com/2025/06/09/h...

Scurvy, all the faces you can see: our experience and review of the literature - PubMed At present, scurvy is a more contemporary condition than previously thought. It is fundamental to recognize both typical and atypical manifestations to avoid delay of diagnosis or rarely life-threaten...

Wow, two papers on scurvy popped up in my alerts today! And here I thought we had finished with this disease in the 1800s. pubmed.ncbi.nlm.nih.gov/40437614/
pubmed.ncbi.nlm.nih.gov/40433577/

Spicy food consumption and biological aging across multiple organ systems: a longitudinal analysis from the China Multi-Ethnic cohort - PubMed Spicy foods may have potential benefits for biological aging. Our findings highlight that spicy foods may slow comprehensive and organ-specific biological aging, especially metabolic and kidney biolog...

Eating spicy food can decrease your biological age? pubmed.ncbi.nlm.nih.gov/40410899/

Frontiers | Creatine supplementation is safe, beneficial throughout the lifespan, and should not be restricted As researchers investigating creatine supplementation, we have become increasingly concerned about reports that government agencies are attempting to restric...

With a title like this you would think that the authors must be paid by the creatine supplement companies- and you'd be right 😉
www.frontiersin.org/journals/nut...

Calf circumference predicts changes of bone mineral density in postmenopausal osteoporotic women receiving denosumab - PubMed In postmenopausal osteoporotic women, the CC was positively and independently associated with denosumab treatment response.

Did you know that your calf muscles are considered your "second heart?" Maybe that's why there's always these weird correlation studies between calf-size and positive outcomes: pubmed.ncbi.nlm.nih.gov/40323522/

Habitual coffee consumption and risk of frailty in later life: the Longitudinal Aging Study Amsterdam (LASA) - PubMed This study examined associations of current habitual and midlife coffee consumption with risk of (pre-)frailty in 1161 community-dwelling older adults (≥ 55 years) participating in the Longitudinal Ag...

Another study correlating coffee consumption and better health: pubmed.ncbi.nlm.nih.gov/40274674/

The mammalian longevity associated acetylome - PubMed Despite extensive studies at the genomic, transcriptomic and metabolomic levels, the underlying mechanisms regulating longevity are incompletely understood. Post-translational protein acetylation is s...

This paper looks pretty interesting! It takes a cross species look (107 different species) at acetylated proteins. If you like NAD and Sirtuins, you should like this paper :) pubmed.ncbi.nlm.nih.gov/40263264/

The Placebo Hypoalgesic Response Is Reduced in Healthy Older Adults Showing a Decline in Executive Functioning - PubMed We demonstrated an age-related reduction in placebo hypoalgesia in older adults showing a decline in executive functioning. This is an important finding, considering the fact that placebo effects cont...

Two interesting findings: 1) the placebo effect is not age dependent and 2) people with cognitive decline are less susceptible to it.
pubmed.ncbi.nlm.nih.gov/40191618/

Antiviral Chewing Gum May Prevent Flu and Herpes Transmission A chewing gum made from lablab beans was effective at neutralizing both influenza and herpes simplex virus (HSV) transmission.

Well this is an interesting idea/result:
www.insideprecisionmedicine.com/topics/patie...

After ‘coding error’ triggers firings, top NIH scientists called back to work Neuroscience institutes tells 10 scientists placed on leave it’s working on a “long-term” solution to officially reinstating them

www.science.org/content/arti...

This administration 🤦🏻‍♂️

More babies born to women over 40 than to teens More women over 40 are giving birth than teens for the first time in history, as teen birth rates hit record lows.

Here's some interesting news- way to go teenagers! www.mother.ly/birth/histor...

Let's hope so.

I can't believe that Luigi Ferrucci, one of the best researchers in aging (objectively by the numbers with over 400k citations), was just fired from the NIA. The USA is going to lose a lot of great scientists and science to other countries 😥

Ohh, a new type of Waymo vehicle- visiting from Michigan apparently!