Carolyn de Graaf

Dear Everyone, I've read the #NHMRC draft strategy and I have notes ...

So I'm going to...🧵🤔🧵😱🧵😵‍💫🧵🙏🧵🧵🧵
This is a repost from X because you all need to know!

#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience

@nhmrc.bsky.social

Secure your early bird rate for Lorne Genome 2026 before Nov 7th! lornegenome.org

We are excited to welcome Prof Duncan Odom as a speaker - a leading researcher in regulatory genomics and cancer genome evolution https://www.lornegenome.org/duncan-odum

Don't forget to register and submit an abstract for the 𝐋𝐨𝐫𝐧𝐞 𝐆𝐞𝐧𝐨𝐦𝐞 𝟐𝟎𝟐𝟔!

𝐓𝐡𝐢𝐬 𝐰𝐞𝐞𝐤'𝐬 𝐬𝐩𝐞𝐚𝐤𝐞𝐫 𝐬𝐩𝐨𝐭𝐥𝐢𝐠𝐡𝐭: 𝐏𝐫𝐨𝐟 𝐁𝐫𝐞𝐧𝐝𝐚 𝐀𝐧𝐝𝐫𝐞𝐰𝐬, a leading systems biologist whose research focuses on mapping genetic interaction networks and protein localisation patterns in yeast and human cells.

Apply to our PhD program!!

Researchers, if you have career disruptions e.g. parental leave 👶, and would like a simple way to calculate full-time equivalent (FTE) years you might like our new calculator, eramezani.github.io/career/ - Written by @eramezani.bsky.social‬ 🙌. Feel free to share around.

Reconfiguration of genome-lamina interactions marks the commissioning of limb cell-fates Diverse forms of heterochromatin block inappropriate transcription and safeguard differentiation and cell identity. Yet, how and when heterochromatin is reconfigured to facilitate changes in cell-fate...

Very excited to share our latest work revealing a prominent role for LADs in commisioning cell fates in mouse organ & tissue development, particularly of the limb. Amazing work by Isabel and Samy together with @stemundi.bsky.social & @drmrobson.bsky.social
www.biorxiv.org/content/10.1...

Creating simple websites with Quarto + GitHub Pages, Wed, May 28, 2025, 5:30 PM | Meetup Want to build your own website in minutes? Join us to learn how to create a simple, stylish website using **Quarto**, and publish it for free with **GitHub Pages**! 🌐✨ Per

Happening today! Learn how to own your digital space by creating your own website FOR FREE using Quarto + GitHub Pages. We will teach you! Join this hybrid event with us ✨ Details below ⬇️ #quarto #GitHubPages #RLadies #Rworkshop

LoxCode in vivo barcoding reveals epiblast clonal fate bias to fetal organs Much remains to be learned about the clonal fate of mammalian epiblast cells. Here, we develop high-diversity Cre recombinase-driven LoxCode barcoding…

A triumph of perseverance from twitterless Tom Weber, Christine Biben and the team, our in vivo barcoding "LoxCode mouse" used to resolve epiblast fate to fetal organs is finally published in @cellpress.bsky.social and available through @jacksonlab.bsky.social www.sciencedirect.com/science/arti...

I had it recommended by a Russian friend as pretty spot on. It would have already been 50 years old when I saw it, but definitely lasted the distance.

@anti-d.bsky.social trying to save Summer by CRISPR screen to block bluebottle "jellyfish" 🪼venom. Identified that it binds via heparinoids - so heparin is potential treatment against pain and cell death caused by it. Also convergent evo as sim pathway in other species 🐍 #lornegenome25

Siu Sylvia Lee - Screen found chromatin factors SET26 and HCF1 as regulators of C elgans lifespan - bind overlapping parts of the genome - possibly by regulating balance of mitochondrial and lipid metabolism genes. #Lornegenome25

Guojie Zhang #lornegenome25 There are > 10k bird species, with lack of consensus of their evolutionary history. Took 363 species (92% familes), developed ref free genome alignment for this giant dataset ➡️ new phylogeny ➡️ rapid evolution and population bottlenecks in some parts of tree 🦚🦃🐔🦅🦉🐦🐦‍⬛

@janstrugnell.bsky.social past breeding history is kept in genomes of animals alive today, so using octopus genomes to test for historic Antarctic ice sheet collapse. Showed that last time global temp was 1.5 deg higher than today the Antarctic ice sheet collapsed #lornegenome #lornegenome25

Learning to catch a wave between sessions #lornegenome #lornegenome2025

Maddy Comerford using massively parallel reporter assay to characterise activity of Denisovan and Neanderthal sequences in the modern genome identifying a denisovan snp with immune specific expression. #lornegenome #lornegenome2025

Ira Deveson - Millenium Prize Winner #lornegenome2025 Assembling a genome with “cornetto” for "no boring bits". Use Oxford Nanopore “read until” to focus extra reads on poorly sequenced parts of the genome to get complete contigs #lornegenome

Heading to #lornegenome25 #LorneCancerConference ? Looking for a computational postdoc to work on spatial and single nuclei transcriptomics of poor prognosis cancers, please DM me or see me at Lorne. We will be advertising soon. @ozsinglecell.bsky.social #LorneCancer2025 #Lorne2025

Our new paper examining how to analyse longread RNA-seq with no reference genome. We compare approaches for assembly and downstream analysis, from transcript accuracy to differential expression. Lead by @alexyfyf.bsky.social. Thnx to all contributors incl. @qgouil.bsky.social for the pea data!