The Lancet Respiratory Medicine

ICYMI: Our new cross-journal Series with @thelancet.com on #Asthma is now live: www.thelancet.com/series-do/as...

Credit: Adria Volta Pinball machine imagery including the lungs and eosinophils

🫁 Explore our October 2025 issue, out now in print and online!

This issue covers a multitude of respiratory and critical care content including mechanical ventilation, #NSCLC, #bronchiectasis, as well as out-of-hospital cardiac arrest.

www.thelancet.com/issue/S2213-...

#respmed #lungsky

300 million people have asthma. A joy co-authoring this @lancetrespirmed.bsky.social MS: Genetic+ environmental risk factors for asthma: towards prevention, led by G Koppelman+G Bruselle with @erikmelen.bsky.social+ M Pino as co-authors @atscommunity.bsky.social authors.elsevier.com/c/1ls9A7tFB1...

Additional Series content 📚

💡Spotlight💡
We also have a Profile of Prof Guy Brusselle who shaped the Series
tinyurl.com/yw9t68e2

🎙️Podcast 🎙
Featuring Professors Porsbjerg and Brusselle to discuss the Series further tinyurl.com/mtwc9ns2

@thelancet.com

1️⃣ Genetic and environmental risk factors for asthma: towards prevention
tinyurl.com/y2w4ez27

2️⃣ Anti-cytokine biologics for asthma in adults
tinyurl.com/334592tf

3️⃣Reframing remission in severe asthma: a conceptual framework for distinguishing disease activity versus damage
tinyurl.com/bdhew5f2

Credit: Adria Volta Alt text: Image representing the complex causal diversity of asthma and its pathways to solutions. These themes are represented by various hallways and staircases leading to biologicals or inhalers. DNA strands are represented, alluding to the advancement of genetic research and some of the most vulnerable social groups (bottom left) who lack access to solutions.

🫁 Asthma 2025 🫁

New Series on #Asthma, launched today at #ERSCongress Check out the Series hub here: www.thelancet.com/series-do/as...

👩‍⚕️ In this Series, we provide new insights into the genetics, prevention, and risk factors of the disease; monoclonal antibody therapeutics; and remission

⏰#ERSCongress ALERT

📰 #Morphine for chronic #breathlessness (MABEL) in the UK: a multi-site, parallel-group, dose titration, double-blind, RCT

This study found no evidence that morphine improves worst breathlessness intensity

Online now and free to access: www.thelancet.com/journals/lan...

Morphine for chronic breathlessness (MABEL) in the UK: a multi-site, parallel-group, dose titration, double-blind, randomised, placebo-controlled trial We found no evidence that morphine improves worst breathlessness intensity. Further research is needed to understand whether there is any role for morphine in chronic breathlessness, but our findings ...

King’s researchers Irene Higginson & @sbajwah.bsky.social contributed to the MABEL trial, published today in @lancetrespirmed.bsky.social, examining the role of morphine in chronic breathlessness.

🔗 www.thelancet.com/journals/lan...

⏰#ERSCongress ALERT

📰 Dupilumab versus omalizumab in patients with chronic rhinosinusitis with nasal polyps and coexisting asthma (EVEREST): a multicentre, randomised, double-blind, head-to-head phase 4 trial

🔓 Online now and free to access for all: tinyurl.com/4nhbtj89

🌍 New @lancetrespirmed.bsky.social!
Pooled sputum testing for TB: revisiting a cost-saving innovation

🚫 Let's bust pooling myths & misconceptions!

🔬 Pooling is efficient, accurate, cost-saving & improves equity of access!

📖 Read at doi.org/10.1016/S221...

Thanks @unitaid.bsky.social for funding!

www.thelancet.com/journals/lan...

Copyright © 2025 Angela Weiss/Contributor The United Nations logo is seen on a fence outside UN Headquarters on September 18, 2025, in New York City. The first day of high-level General Debate for the 80th session of the UN General Assembly will begin on Sept 23, 2025

💡New Spotlight: Chronic respiratory diseases and inhalers in Africa

Esther Nakkazi reports on chronic respiratory diseases as a neglected health crisis ahead of the 4th High-level Meeting of the UN General Assembly in New York on Sept 25, 2025

tinyurl.com/yejfbz2v

Credit: Adria Volta Image representing the complex causal diversity of asthma and its pathways to solutions. These themes are represented by various hallways and staircases leading to biologicals or inhalers. DNA strands are represented, alluding to the advancement of genetic research and some of the most vulnerable social groups (bottom left) who lack access to solutions.

🌉 Only a few days now until #ERSCongress in Amsterdam!

📰 We will be launching our new cross-journal Series with @thelancet.com on #asthma on 30th September at 10:15 CEST

📅The Lancet Group will be publishing plenty of new respiratory content during the conference so keep an eye out for updates!

📈 New phase 3 trial in #lungcancer

Retifanlimab vs placebo with platinum-based chemotherapy in patients with first-line metastatic non-small-cell lung cancer (POD1UM-304)

Retifanlimab improved overall survival compared with placebo when added to platinum-based chemotherapy

tinyurl.com/483jf7k8

Credit: H. Armstrong Roberts/ClassicStock

📚 New Editorial

Farming life: a double-edged sword for respiratory health

The #farming environment is an exemplar of disparate and antagonistic influences on respiratory health

www.thelancet.com/journals/lan...

Chrysotile asbestos fibers Copyright © 2025 Science Stock Photography / Science Photo

💡Spotlight

Chrysotile asbestos—the deadly consequences of a retreat from national bans

"There is no safe level of asbestos, whether chrysotile or amphibole, and global bans remain the only solution to this ongoing devastating occupational health tragedy"

tinyurl.com/5n7rctz2

Credit: Adria Volta

📰The Lancet Respiratory Medicine’s September issue is out now

Read content on obstructive sleep apnoea, #tuberculosis, cardiogenic shock, #pneumonia, and much more

Check out the full issue here: bit.ly/3P2PVls

Images of police officers and police cars around cordoned off area at CDC headquarters. Credit: Elijah Nouvelage / Stringer

🗞️ News

Vaccine disinformation motivated gunman's attack on US CDC headquarters

@bryantfurlow.bsky.social

tinyurl.com/mu2nen8d

Undoing progress through sudden tuberculosis funding cuts Tuberculosis remains the world's leading infectious killer, resulting in more than 1·25 million deaths in 2023 alone.1 During the past decade, efforts to end tuberculosis have achieved important miles...

Abrupt funding cuts to international aid are disrupting essential tuberculosis (TB) services. Ending TB remains within reach—but only with adequate adaptation, investment, and will.

New Comment ⤵️
tinyurl.com/2xccptr5

🌎 Symposium Spotlight

Join us at the Union World conference on Lung Health for a critical symposium with The Lancet Global Health Commission on Medical Oxygen Security.

🗓️18 November 2025
⏰ 11:30 - 13:00

📰 The US FDA has approved the first immunotherapy for recurrent respiratory papillomatosis tinyurl.com/3db69ye4

Approval is based on a pivotal phase 1/2 clinical trial of PRGN-2012 gene therapy published in @lancetrespirmed.bsky.social

🔗 Check out the full trial results here: tinyurl.com/yzjdc665

Image of Yvonne Hughes

💡New Spotlight

Unique perspective on cystic fibrosis at @edfringe.bsky.social

by Peter Ranscombe

tinyurl.com/5r8sykbn

📄✨ New publication! A @lancetrespirmed.bsky.social study co-authored by #AusHSI Prof Stephanie Yerkovich and Prof Anne Chang highlights geographical variations in childhood bronchiectasis and its management using data from the international Child-BEAR-Net Registry.

🔗 Read the paper: bit.ly/46RdLdx

Trump administration decimates worker health oversight The Trump administration's sweeping deregulation, funding cuts, and layoffs are undermining workplace respiratory health protection and research, leaving employees—particularly miners and firefighters...

The Trump administration’s sweeping deregulation, funding cuts, and layoffs are undermining workplace respiratory health protection and research, say experts.

Explore what it means for workers in @lancetrespirmed.bsky.social ⤵️
bit.ly/3J7jW3d

Copyright © 2025 Jim West/Science Photo Library Image showing costruction workers with appropriate PPE and protections in place

🗞️ News from the US covered by @bryantfurlow.bsky.social

Trump administration decimates worker health oversight tinyurl.com/3kpx4fdf

US FDA authorises Juul e-cigarette marketing, imperilling youth #vaping declines
tinyurl.com/23hn996v

New Comment - Pre-#COPD: an evolving concept with practice potential

The concept of pre-COPD holds strong potential for both clinical and public health strategies

🔗 tinyurl.com/4a6wtcds

🎙️For new followers, our Podcast is a monthly audio companion to the journal, covering all things respiratory and critical care, from #longCOVID to #tobacco control, #asthma, #TB, #sepsis, and more

🎧Listen to previous episodes here: www.buzzsprout.com/admin/145996...

#lungsky #MedSky

So honoured and humbled to be profiled by @lancetrespirmed.bsky.social

📑 New Article available #OpenAccess

Type 2 inflammation biomarkers and their association with response to dupilumab in #COPD (BOREAS): an analysis of a randomised, placebo-controlled, phase 3 trial

tinyurl.com/b34yzm3v

#lungsky #respmed

Conceptual image showing the risk factors for lung disease. Image includes a globe, lit cigarette, cross section of the inside of a lung, and someone using an inhaler. Copyright: Adrià Voltà.

📚 August issue of The Lancet Respiratory Medicine out now!

Read the full issue here: lnkd.in/eh_i8K2k

This issue includes groundbreaking research on #NSCLC, #COPD, and #bronchiectasis, alongside important discussion on a variety of #respiratory and #criticalcare topics