Zheng Shi

🚀The #BiomembraneDays2025 concluded

WE THANK ALL PARTICIPANTS & OUR SPONSORS🙏🙏🙏

@abberior.rocks
Critical Insights in Biophysics
Ernst Rudolf Schloeßmann Foundation
@dfg.de
@jcellsci.bsky.social
@lipotype.bsky.social
@naniontech.bsky.social
@picoquant.bsky.social
Refeyn Ltd
@biologists.bsky.social

That’s great, thanks Helge!

Can’t believe Germany 🇩🇪 has an entire day off so that people can listen to the new Taylor Swift album 🎧🎶 😂

Any lab here open to hosting a visiting scientist next year?
For someone who is interested in advanced microscopy and cellular mechanics (and can still do experiments 🙋)?

Look what I found in Berlin!

Aka, “cell membranes resist flow”😉

Wish @adamezracohen.bsky.social and @sorkinlab.bsky.social were here!
Here is the authors’ reaction:

Something magical happened at #BiomembraneDays2025 today! The speaker (Tanmoy Ghosh) showed two papers in his slide, and it just happened that the authors of the two papers were sitting right next to each other among hundreds of people listening 😁. #BiomembraneDays25

Having a blast at #BiomembraneDays2025!

Here is a fun little note: scientists profile pictures should always go with clearly labelled names…

Well, unless it’s Albert Einstein.

Afternoon session of #BiomembraneDays2025 starts with Zheng Shi and a genuine fluorescent sensor for membrane tension.

We continue the #BiomembraneDays25 with Zheng Shi @zs-biophys.bsky.social who presented nice work on mechanosensors and membrane tension.

Thanks Helge!

When you submit an abstract for #bps2026 you're not only sharing your work, you're:
🤝 connecting with your community
✍️ getting important feedback
📊 hearing the latest from your own and related fields
💻 learning about emerging technologies
🧑‍🏫 accessing career development workshops
buff.ly/ckmwI4E

Vielen Dank an die tollen Organisatoren😉

Biomembrane Days 2025 Membranes form the intricately shaped compartments of life. The Biomembrane Days are a triannual workshop that highlights recent advances in understanding the morphology and molecular organization of ...

Looking forward to the Biomembrane Days next week!

I’m supposed to learn basic German but I ran into @markusdeserno.bsky.social at the airport. Now I’m wasting time on social media 😂

events.mpikg.mpg.de/event/15/

See you in Berlin Markus!

Tenure-track Position in Biophysics at Carnegie Mellon University, Department of Physics Location: Pittsburgh, PA Open Date: Sep 19, 2025 Description The Department of Physics at Carnegie Mellon University invites applications for a tenure-track faculty position in biophysics. The appointment is intended to be at the Assistant Professor level, but exceptional candidates at a higher level may also be considered. We seek outstanding candidates with a strong record in cellular and subcellular biophysics. Topics of particular interest include, but are not limited to, uncovering how key characteristics of living systems arise from the interplay between supramolecular cellular structures, how the emergent cellular circuitry defines goals and enables robust decision making, and how metabolic resources are allocated. This encompasses understanding of how information is learned, stored, transduced, and processed across subcellular structures. Applicants with theoretical, data science, or experimental backgrounds within biological physics are encouraged to apply. The ideal candidate will strengthen and extend research programs of current biophysics faculty in the Department of Physics and collaborate with broader life science activities across many departments at CMU and the wider Pittsburgh area. More details on Interfolio: https://apply.interfolio.com/174360

I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪

Interfolio link: apply.interfolio.com/174360

PLEASE, share widely across the blue skies!

Let me briefly explain what we're looking for:

1/10

yeah, that's probably why we study biophysics in a chemistry department 😅

I do find the analogy between Chemistry and New Jersey amusing - both are like a keg that had been tapped at both ends😂

Who Exactly is a

The last sentence summarizes my feeling to the question of "who exactly is a real chemist"...

"Do you want to spend more time feeling like real inside members of a pure and defined club, or do you want to discover things?"

Who Exactly is a "Real Chemist"? | Science www.science.org/content/blog...

Nuclear mechanics as a determinant of nuclear pore complex plasticity - Nature Cell Biology In this Review, Lusk et al. discuss emerging insights into nuclear pore complex variability with regard to composition and dilation state, and propose nuclear mechanics as a key determinant of driving...

Did you know that all nuclear pore complexes (NPCs) are not the same? @luskinglab.bsky.social propose a new hypothesis for how nuclear mechanics may impact the compositional plasticity of NPCs with implications for tissue-specific diseases caused by NPC dysfunction.

www.nature.com/articles/s41...

Tau accelerates tubulin exchange in the microtubule lattice - Nature Physics Beyond its known role in stabilizing microtubules, it is now shown that tau protein actively promotes lattice defect repair by enhancing tubulin turnover at topological defects.

Excited to share that my paper on Tau–Microtubule interactions is now published in Nature Physics!🎉

Our work shows that tau goes beyond stabilizing microtubules—it also promotes the removal of defects in the microtubule lattice.

www.nature.com/articles/s41...

Thanks to the Cornell Chronicle for highlighting our work! news.cornell.edu/stories/2025...

Electrophysiology in small compartments Voltage-gated ion channels are found in many membrane-enclosed structures, including synaptic vesicles, endosomes, mitochondria, chloroplasts, viruses and bacteria. In small compartments, assumptions ...

In small enclosed structures (like vesicles), the flickering of individual ion channels can have substantial effects on membrane voltage and internal ion concentrations. Mean-field conductance-based models break down. We studied what happens:
www.biorxiv.org/content/10.1...

I saw the preprint title and thought “oh, I should send this to Adam” :)

Ah, I was looking at it upside down 😅, thanks!

Yes! There is a small ester egg when you find where the crossing points exactly are:)

Ah, could be!

How often do you buy a book, then the author makes a series of free videos to help you read/understand the book?!
Check out @longformmath.bsky.social 's Youtube videos (youtu.be/2QcJB-Yl7h8?...),
On a related note, guess how many times the red and black lines cross with each other😉

Thanks for sharing! Is there a reason that the PM is drawn to be slightly curving into the cell? (sorry haven't yet read the paper in detail)

Thanks Markus, I’m pretty sure I need both :)