Max Gutierrez

YouTube video by KeystoneSymposia KSQA: Dr. Max Gutierrez (Tuberculosis)

🔬 TB, infectious disease & global health researchers: Save $250 by registering for the Keystone Symposium on Tuberculosis by Jan 22 (11:59 PM MST). Join leaders in TB biology & global health. 🎥 youtu.be/4L_N79rDCfw
🔗 keysym.us/KSTB26
@maxgg.bsky.social @breealdridge.bsky.social #KSTB26 #TBResearch

Continuum architecture dynamics of vesicle tethering in exocytosis Data from complementary imaging techniques were integrated into a model that resolves the dynamic exocyst ensemble and membrane architecture during exocytosis, an essential cellular pathway. Sec18 med...

0/10
🥳 our #exocyst paper out in @cp-cell.bsky.social, led by Marta, Sebas & @sasmeek.bsky.social in collab with @jonasries.bsky.social, @cmanzo.bsky.social & Castaño-Díez labs #Quantitative_Cell_Biology

Continuum architecture dynamics of vesicle tethering in exocytosis
www.cell.com/cell/fulltex...

Congratulations Oriol and the team! Beautiful work!👏

Interested to see what each face will give you after swabbing and doing CFUs

🥳 𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐥𝐚𝐭𝐞𝐬𝐭 𝐰𝐨𝐫𝐤 𝐬𝐡𝐨𝐰𝐢𝐧𝐠 𝐡𝐨𝐰 𝐩𝐨𝐥𝐲𝐬𝐢𝐚𝐥𝐲𝐥𝐚𝐭𝐢𝐨𝐧, 𝐚 𝐫𝐚𝐫𝐞 𝐩𝐫𝐨𝐭𝐞𝐢𝐧 𝐦𝐨𝐝𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧, 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐞𝐬 𝐢𝐧𝐟𝐥𝐚𝐦𝐦𝐚𝐭𝐨𝐫𝐲 𝐦𝐨𝐧𝐨𝐜𝐲𝐭𝐞 𝐦𝐨𝐛𝐢𝐥𝐢𝐳𝐚𝐭𝐢𝐨𝐧 𝐟𝐫𝐨𝐦 𝐭𝐡𝐞 𝐛𝐨𝐧𝐞 𝐦𝐚𝐫𝐫𝐨𝐰.

✍️ Aurélien Boyancé, Nelly Gilles, @yoannrombouts.bsky.social & coll. @ipbstoulouse.bsky.social

📖 shorturl.at/IDwza

👇 A short thread...

A great meeting ahead for host and pathogen aficionados! Keynote speakers: Florence Niedergang (Cochin) and Raphael Valdivia (Duke)- plenty of opportunities for early career researchers to present their work and a very collegial and supportive network. Belfast here we go! Please repost.

🧐”Study reveals how #tuberculosis exploits immune defenses to promote infection.”
🔗to study published in Science Immunology ⬇️
Mycobacterial α-glucans hijack dectin-1 to facilitate intracellular bacterial survival
www.science.org/doi/10.1126/...

Very relatable. Number of items and system is similar. Only difference is that I do account for the time every item needs (e.g. from 1h to one day and level of distraction allowed), I add deadlines to them too. sigh 😂

Scientists at MRC CMM & collaborators discover how Mycobacterium tuberculosis harnesses the immune system to cause infection.

Gordon Brown @mrccmm.bsky.social Claire Hoving @uct-fhs-research.bsky.social @maxgg.bsky.social @crick.ac.uk @wellcometrust.bsky.social

Read more:

I am thrilled to share that the work from @maxgg.bsky.social team @crick.ac.uk engineering a lung-on-chip from human iPSC is published in #ScienceAdvances @science.org in the new year.

Thanks Jenny!

Congratulations (again) Angélique!👏

I am happy to share that the work from @maxgg.bsky.social at @crick.ac.uk engineering a lung-on-chip from human iPSC is published in #ScienceAdvances @science.org in the new year.

Thanks Gabriele! 😀

Very happy to see this out! Work led by
@jaksonluk.bsky.social together with an amazing team @crick.ac.uk Jakson et al established a scalable and reproducible multicellular system based on human stem cells to mimic the human alveolar space in a micro-physiological system. Congratulations everyone!👏

Thanks Jeremy! 😃

Built to breathe: mini ‘lungs’ recreate individual response to infection Lung-on-chip device exposes earliest stages of tuberculosis infection, and opens doors to investigate diversity in disease progression and personalised treatment.

Lab-grown lung models have traditionally been grown from a mixture of cells, making it hard to tell how a disease or treatment will affect an individual person.

These new models by @maxgg.bsky.social’s team and AlveoliX are grown from a single person’s stem cells ⤵️ www.crick.ac.uk/news/2026-01...

Last couple of days to vote for your favourite 'Featured image' from 2025 ❤️🔬!
focalplane.biologists.com/2025/12/19/v...

Pre-Christmas vibes at @crick.ac.uk 🎄

Why solutions to antimicrobial resistance are urgently needed Summary: This Editorial discusses the growing global problem of antimicrobial resistance, and new and emerging opportunities for developing real-world solutions, involving both basic science and clini...

‘Why solutions to antimicrobial resistance are urgently needed‘ sergemostowylab.bsky.social & I had the opportunity to write an editorial for @dmmjournal.bsky.social ‘s collection celebrating 100 years of @biologists.bsky.social you can read it here: journals.biologists.com/dmm/article/...

Mycobacterium tuberculosis overcomes phosphate starvation by extensively remodelling its lipidome with phosphorus-free lipids - Nature Communications Here, the authors show that Mycobacterium tuberculosis manipulates lipid metabolism to overcome host restriction, by remodelling its lipidome and utilising host lipids as an alternative phosphate sour...

We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development.

www.nature.com/articles/s41...

A thread.

A new role for lipoproteins LpqZ and FecB in orchestrating mycobacterial cell envelope biogenesis | mBio Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), remains the world’s deadliest bacterial infection, in part because the bacterium’s unique cell envelope makes it highly resistant to antibioti...

Of course I like all the papers that we publish, but this is actually a very cool story, a great example of 'bush mechanics' in mycobacteria.
A new role for lipoproteins LpqZ and FecB in orchestrating mycobacterial cell envelope biogenesis | mBio journals.asm.org/doi/10.1128/...

Academia is just a job. And you need 29.95 quid to find out why...

Good point. Much easier than that! I am at the state where I can only remember the name of the person and barely one word related to the email and cannot find it 😅

YouTube video by KeystoneSymposia Tuberculosis Meeting Promo

📢 Early-Career TB Researchers: Submit short talk abstracts & scholarship apps by Nov. 24! Join us Mar 23-26, 2026 in Cape Town for cutting-edge TB & global health. 🎥Highlights: youtu.be/YcKVeGWqXSM
Submit: keysym.us/KSTB26
@maxgg.bsky.social @breealdridge.bsky.social #KSTB26 #tuberculosis #TB

2021 sounds modern times to me 🤣

In the era of chatGPT, Claude, Grok, DeepSeek, Perplexity etc and finding an email in outlook using keywords is literally impossible….

👇👇Last days to submit your abstract to be considered for a short talk! Deadline 24 November!https://www.keystonesymposia.org/conferences/conference-listing/meeting/travel/c42026

PhD training needs a reboot in an AI world As machines get better at data analysis and writing tasks, doctoral training must evolve to make the most of artificial-intelligence outputs.

...Students will need to develop sufficient expertise to identify when AI systems produce plausible but incorrect outputs — which poses a dilemma because this requires the very skills that AI is starting to replace...
www.nature.com/articles/d41...

VPS13C/PARK23 initiates lipid transfer and membrane remodeling for efficient lysosomal repair Perturbations in lysosome integrity are tightly linked to neurological disorders and ageing, but the underlying pathogenic mechanisms are incompletely understood. Using an unbiased proteomic approach,...

Proud to share a preprint of our paper on how bridge-like lipid transport protein VPS13C senses lysosomal membrane tension in anticipation of membrane lesions to initiate net ER-to-lysosome lipid transfer for efficient lysosomal repair www.biorxiv.org/content/10.1...