Sandhya Koushika's Avatar

Sandhya Koushika

@wormlockholmes.bsky.social

Cellular neurobiologist TIFR India who loves genetics, live imaging and worms. Science is fun, let's go exploring. Sci comm, write bad poetry, 2 girl mom lab: https://tinyurl.com/5n7s6ens https://scholar.google.co.in/citations?user=c4zDSQ8AA

2,422 Followers  |  476 Following  |  275 Posts  |  Joined: 19.10.2023  |  1.8899

Latest posts by wormlockholmes.bsky.social on Bluesky

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Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance Plasmids are now the primary vectors of antimicrobial resistance, but our understanding of how human industrialisation of antibiotics influenced their evolution is limited by a paucity of data predati...

Super interesting-dig in

Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance | Science www.science.org/doi/10.1126/...

27.09.2025 01:36 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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The curious case of the tigers who changed their stripes A century ago, Indiaโ€™s tigers were on the brink of extinction. Slowly, their numbers have rebounded. But that ecological success has prompted a dire problemโ€”and a race to save many of them from geneti...

A 19-page article in the National Geographic that covers the work of @uramakri.bsky.social @ncbsbangalore.bsky.social @tifr.res.in on black tigers, mutation load and corridors for tiger migration.

Important story and impactful work.
๐Ÿ‘๐Ÿพ

www.nationalgeographic.com/animals/arti...

16.09.2025 03:23 โ€” ๐Ÿ‘ 2    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

What a feast....

01.09.2025 15:01 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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This award aims to highlight outstanding research by active neuroscientists working in countries underrepresented in neuroscience publications and conferences. @network-alba.bsky.social @sfn.org @ibroorg.bsky.social @fens.org

21.08.2025 16:01 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Our worm lab is recovering from a mite attack. Trainees devoted hours to cleanup

A mite or two or an army
They are hateful and smarmy
Our helpless little ones
Crushed by their whirling carny

Hello give up not
Gather all the stock
Pick, bleach, clean
Burn to death a game well fought

21.08.2025 09:03 โ€” ๐Ÿ‘ 11    ๐Ÿ” 1    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0
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๐ŸšจOnly 4 days to apply!!!๐ŸšจJoin the SDB SciComm Internship! Gain hands-on experience writing stories on the latest developmental biology discoveries๐Ÿ”ฌConnect with top mentors & earn $500 to attend the SDB Annual Meeting ๐ŸŽ‰! ๐Ÿ‘‰ www.sdbonline.org/science_comm... #SciComm #DevBio

12.08.2025 13:29 โ€” ๐Ÿ‘ 13    ๐Ÿ” 11    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 3

Thank you--this is cool

12.08.2025 07:09 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

How widespread is heat-dependent sterility. Is this only in C. elegans? Does it happen in other nematodes or other cold-blooded animals?

12.08.2025 06:23 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Foliar mRNA spray induces protein synthesis in monocot crop and dicot model plant species In planta gene expression via exogenous mRNAs has a wide range of potential biotechnological applications from genome editing to plant protection and to circumventing tissue culture. Yet, regarding mR...

๐Ÿ˜ฎ Just WOW!!

Spray GFP mRNAs on plant leaves and the leaves translate this and you get glowing leaves.

www.biorxiv.org/content/10.1...

12.08.2025 06:22 โ€” ๐Ÿ‘ 51    ๐Ÿ” 12    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 5

Really interesting preprint on how the nervous-system modulates heat-dependent fertility. Work from @ethanewe.bsky.social from @odedrechavi.bsky.social lab. May well be relevant in a planet that is heating up.

12.08.2025 06:15 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Loved this @heiman.bsky.social

11.08.2025 05:40 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Read today

"Comparison is the thief of Joy"

True that

09.08.2025 14:27 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Our dept @tifr.res.in โ€ฌran an MSc by research for ~25yrs. Our last batch graduated this month. Several headed to excellent PhD programs, some to jobs.

Congratulations and good luck for many fun adventures.

๐Ÿ‘๐ŸพSohan Seal from my lab headed for a PhD to @mpi-cbg.de. 2nd from L, row 2

30.07.2025 10:07 โ€” ๐Ÿ‘ 9    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ˜” Doing science has taken on elements of a corporation w/ writing=one "vertical". Output of research as patents and IP seems to be another. Metrics is a temple at which we worship at.

Sometimes overlooked is serendipity, small groups that meander & in this context the idea that writing is thinking.

10.07.2025 07:30 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Important.......

08.07.2025 23:30 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

โญ ๐ŸŒŸ image

08.07.2025 16:12 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Organ clocks for post-menopausal women taking estrogen or not taking estrogen

Organ clocks for post-menopausal women taking estrogen or not taking estrogen

New organ clock data support the anti-aging benefits of estrogen for postmenopausal women. Reviewed here in context with previous and other recent reports.
erictopol.substack.com/p/new-anti-a...

05.07.2025 17:09 โ€” ๐Ÿ‘ 286    ๐Ÿ” 57    ๐Ÿ’ฌ 17    ๐Ÿ“Œ 4
Worm Show 2025
YouTube video by Morris Maduro Worm Show 2025

Bummed I missed the worm meeting this year but happy Worm Show was posted on YouTube. Bravo Morris and Curtis! www.youtube.com/watch?v=HXgU...

05.07.2025 02:39 โ€” ๐Ÿ‘ 9    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

We are looking forward to the Worm Meeting 2027 and thank
Suhong Xu(Zhejiang University School of Medicine, Hangzhou, China),
Kavita Babu (Indian Institute of Science, Bangalore, India), and
Erik Andersen (Johns Hopkins
University Baltimore, USA)
for organising. #worm25

02.07.2025 18:34 โ€” ๐Ÿ‘ 36    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Worms with neurons, a bracelet? Promise to buy. Missing #Worm25

02.07.2025 07:22 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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As itโ€™s my first time joining Worm Meeting, I was excited to participate in Worm Art show as well.
This yearโ€™s topic is resilience. In times of scarcity, worms gather holding one another to reach new grounds. Alone - they are fragile, together - they rise. Even the sky yields in unity. #worm25

27.06.2025 04:20 โ€” ๐Ÿ‘ 40    ๐Ÿ” 10    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 1

Role of clathrin adaptor complex AP3 in secretion of dense core vesicles from the Sahu lab, NBRC.

Badal from my lab has added an experiment testing the role of AP3 in secretion of neuropeptides in C. elegans.

02.07.2025 06:08 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

โค๏ธ

30.06.2025 10:22 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Favorite moment of the day: "Do Genetics" -Nobel Prize Winner Gary Ruvkun #worm25

30.06.2025 06:26 โ€” ๐Ÿ‘ 25    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
WormBase site will be frozen and migration to Genome Alliance

WormBase site will be frozen and migration to Genome Alliance

Paul Sternberg with important WormBase news #worm25

29.06.2025 03:47 โ€” ๐Ÿ‘ 26    ๐Ÿ” 11    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 4

Folks at #worm25 please post. For those of us who did not make it we have to experience it vicariously through your posts.

30.06.2025 09:53 โ€” ๐Ÿ‘ 17    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

โ€œDo you have any advice for aspiring young scientists?โ€

โ€œDo genetics.โ€ *mic drop*

#worm25

30.06.2025 02:01 โ€” ๐Ÿ‘ 92    ๐Ÿ” 22    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

For #worm25, here are updated lists of 200+ researchers for the #Celegans community to easily follow:

C. elegans #1 (150 full) - go.bsky.app/HP1h3nW
C. elegans #2 (50+) - go.bsky.app/J7soTHG

==> Reply to this if you'd like to be added!

cc: @genetics-gsa.bsky.social

#CeleganSky ๐Ÿชฑ ๐Ÿงช 1/n

29.06.2025 19:20 โ€” ๐Ÿ‘ 35    ๐Ÿ” 21    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 1

๐Ÿ‘Œ๐Ÿฝ

30.06.2025 01:43 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Nice study

27.06.2025 10:00 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@wormlockholmes is following 20 prominent accounts