Chaz Hong MD PhD

Miracle drugs don’t come out of nowhere — Harvard Gazette Healthcare, innovation experts say funding cuts to university labs will slow or stop basic research on which breakthroughs are built.

Spot on…for all cures - past, present & future -come from research. #SaveNIH

NIH Funding Has Stagnated Since 2003 This Viewpoint explores how funding has changed at the National Institutes of Health over time and discusses how continued investment is necessary to maintain the current level of biomedical research.

"Maintaining our current level of progress in biomedical research requires continued additional investment simply to keep pace."

This Viewpoint explores how funding has changed at the US National Institutes of Health (NIH) over time. https://ja.ma/3RQPP11 #MedSky

Thank you to organizers of 1st Ferroptosis conference in US. We learned so much! Congrats to Brent Stockwell, who coined the term! Our work on novel mechansim of #ferroptosis regulation by GPCR & its therapeutic potential will add to this area! Stay tuned! #SpartansWill
@msu-medicine.bsky.social

Honor to give psychiatry lecture on phenotypic approach to drug discovery at Pine Rest Christian Mental Health Services, 2nd largest of its kindl! We need to find paths for new therapies in psychiatry. Our patients & loved ones are waiting. Thank you, Dr. Nagy Youssef for hosting me. #SpartansWill

graph of NIH basisfor new drugs

A pie graph worth keeping in mind as the NIH budget plummets jamanetwork.com/journals/jam... for 356 new FDA drugs approved

Meanwhile, exercise, low sodium diet, statins, BP meds, and vaccines go underutilized or out of reach of millions....

State interference: How not to do science.
Lysenko convinced Stalin to reject genetics in favor of #Lamarkism, leading to disastrous effects on Soviet economy.

USA's “Secret Sauce," is our Research Universities & Academic Freedom, now threatened by political interference. #StandUpForScience2025

Is "batshit crazy" a swear word?

I just couldn't help myself...

This is a head scratcher. All I did was post that "without research, we're doomed." Or maybe mock Elon for mocking hard working Americans?

#StandUpforScience2025

Years ago, using chemical genetics in zebrafish, I elucidated the role of #PI3K in vein specification. Just spoke to someone who has #VenousMalformation d/t somatic activating mutation in PI3K subunit. Learning how this knowledge is helping him made my day! #SpartansWill
@zebrafishrock.bsky.social

What batshit crazy stuff are they saying?! This is like blaming Poland for Hitler & Stalin’s invasion in 1939! #StandWithUkraine

Come join an amazing department.

A bold move by MSU! "A more unified approach to medical education supports the creation of a critical mass of talented clinician scientists to enable high-impact research, attracting funding, & increasing institutional reputation.” #SpartansWill
www.healthsciences.msu.edu/one-team-one...

Assistant/Associate/Full Professor Tenure System - East Lansing, Michigan, United States - Grand Rapids, Michigan, United States Working/Functional Title Assistant/Associate/Full Professor Tenure System Position Summary The Department of Medicine at Michigan State University is making a transformative investment to build our re...

WE'RE HIRING!! @msu-medicine.bsky.social
is recruiting outstanding #CancerBiology scientists, especially those w/ expertise in #CancerImmunology, #CancerMicroenvironment, #TumorMetabolism, & #NutritionMicrobiome tumorigenesis links. #SpartansWill
careers.msu.edu/jobs/assista...

Millions, maybe you also, are alive & well today because of research.
Medicine without Reasearch is just Sorcery…
#SaveNIH

NIH Budget Cuts Are a “Short-Sighted” Setback for US Science An NIH policy to reduce funding for indirect costs to 15 percent, although temporarily blocked nationwide, sparks widespread concern and criticism among scientists.

www.the-scientist.com/nih-budget-c...

Henry Ford + MSU researchers collaborate to shift pancreatic cancer outlook from bleak to bright Henry Ford Health and MSU researchers are teaming up to change the outlook for pancreatic cancer patients. With cutting-edge research on genetic indicators and promising RAS inhibitors, the team is wo...

Collaboration b/t our super star recruit @jennyklomp.bsky.social & @henryfordhealth.bsky.social
colleague @hccvpdac.bsky.social will brighten the outlook for pancreatic cancer patients!! #SpartansWill
@nullalleles.bsky.social @msu-medicine.bsky.social
msutoday.msu.edu/news/2025/he...

Spent the first day at my new office in Doug Meijer Medical Innovations Building in Grand Rapids. Three of us from @msu-medicine.bsky.social are the very first occupants of this awesome space! Bit lonesome here, so we’re hiring! And is Detroit next? Stay tuned! #SpartansWill!

Inhibition of GPR68 induces ferroptosis and radiosensitivity in diverse cancer cell types Scientific Reports - Inhibition of GPR68 induces ferroptosis and radiosensitivity in diverse cancer cell types

Hong lab is on a roll in 2025! Our latest paper showing GPR68 inhibition induces #ferroptosis & #radiosensitivity in diverse cancer cell types like lung & pancreatic cancer cells. Therapeutic synergy with radiation therapy. #SpartansWill rdcu.be/d8rGf

New grant ideas for 2025 NIH:

"Genetic disorders: Accident or reason to blame your parents"

"Fluoride, mind control drug or drug to control your mind"

"Polio, was it really that bad?"

Cool visualization of ERK activation! @jennyklomp.bsky.social & @nullalleles.bsky.social

anatomypubs.onlinelibrary.wiley.com/doi/epdf/10....

w/ pH-sensing probe, we visualize acidic microdomains in tissues of live whole animals, including extracellular spaces of myotome & w/i T-tubules, opening up cool questions regarding their role in health & disease. Link to paper 👇. #SpartansWill.
@zebrafishrock.bsky.social @msu-medicine.bsky.social

Truly thankful to Will & his mother Emily who has glioblastoma, for visiting our lab at MSU & sharing their experience of living with GBM & wonderful care they received at @henryfordhealth.bsky.social We learned so much & are inspired by your courage. #SpartansWill
@msu-medicine.bsky.social

Been nursing a nasty head cold. Whoever design these medicine packets deserve to be put in a special purgatory.

Blue birds huddling together for warmth

Mass General Brigham Researchers Find Too Much Sitting Hurts the Heart New study shows that being sedentary increases the risk of the most common types of heart disease, even among those who get enough exercise .

“Too much sitting hurts the heart, while ‘fart walk’ after meal protects the heart.” Did Confucius write this?