Santhi K. Ganesh, MD

@pdmace2.bsky.social @jasonkovacic.bsky.social @heatherlgornik.bsky.social @n-bouatia-naji.bsky.social @markelindsay.bsky.social

We are thrilled to share that Michigan Medicine has been awarded a new, international research grant for more than $8.5 million by the Leducq Foundation to advance research into fibromuscular… | Michi... We are thrilled to share that Michigan Medicine has been awarded a new, international research grant for more than $8.5 million by the Leducq Foundation to advance research into fibromuscular dysplasi...

Honored and grateful to receive transformative support from the 𝗟𝗲𝗱𝘂𝗰𝗾 𝗙𝗼𝘂𝗻𝗱𝗮𝘁𝗶𝗼𝗻 of our research on 𝗙𝗶𝗯𝗿𝗼𝗺𝘂𝘀𝗰𝘂𝗹𝗮𝗿 𝗗𝘆𝘀𝗽𝗹𝗮𝘀𝗶𝗮. Excited to begin work with our 𝗔𝗟𝗜𝗚𝗡-𝗙𝗠𝗗 Network and proud to partner with Jason Kovacic, Stéphanie Debette, Nabila Bouatia-Naji, Manuel Mayr, and Mark Lindsay. #FMD

Comparison of Research Spending on New Drug Approvals by the NIH vs the Pharmaceutical Industry This cross-sectional study examines National Institutes of Health and pharmaceutical industry investments in recent drug approvals.

99% of new medicines developed by the pharmaceutical industry depend on NIH research jamanetwork.com/journals/jam...

From Science Advances - a new collection on Advancing the Science of Women’s Health. www.science.org/toc/sciadv/c...

Heart disease in women is far too often misdiagnosed or dismissed

A (not so) shocking 84% of female cardiologists surveyed reported treating women whose symptoms were ignored or misdiagnosed

This is disgraceful. Advocate for better awareness.
#CVprev #Cardiosky
#HeartAndSoul

This account is for sharing info with US scientists, both extramural and intramural to NIH, about attacks on science in the US.

Education is power, and we can help advocate for science and medicine together. 💪🧪

We are a team of NIH people. Please ask us questions you might have.

Pregnancy-Associated Myocardial Infarction in Alberta: A Population-Based Study Cardiac disease is the leading cause of maternal mortality in developed countries, and myocardial infarction (MI) is an important cause of pregnancy-a…

www.sciencedirect.com/science/arti... #SCAD

Arterial Hypertension in Women: State of the Art and Knowledge Gaps | Hypertension Hypertension is the leading risk factor for cardiovascular disease and premature death among women globally. However, there is a fundamental lack of knowledge regarding the sex-specific pathophysiolog...

www.ahajournals.org/doi/10.1161/... #FMD

Umich faculty with NIH funding: please DM me if you’re hearing of study section disruptions in your subfield.

Pretty neat - the placenta-tropic lipid nanoparticle formulation had an order of magnitude greater mRNA delivery than current standards.

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia - Nature A platform for mRNA lipid nanoparticle delivery to the placenta to treat pre-eclampsia is shown to improve fetal and maternal health in mice and has potential clinical applications in obstetric d...

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia

www.nature.com/articles/s41...

A New Vision for Women's Health Research: Transformative Change at the National Institutes of Health Read online, download a free PDF, or order a copy in print.

Agree 💯 that more work is needed to address gaps in women's health research in the recent National Academies report, including CVDs.

www.science.org/content/arti...

nap.nationalacademies.org/download/28586

Applications are now OPEN for the 2025 Human Genetics and Genomics GRC and GRS!! 🎉 🧬

📅 GRS: July 5-6, 2025
📅 GRC: July 6-11, 2025
📍 Portland, Maine

@calliao.bsky.social and I are co-chairs for the GRS, with Shamil Sunyaev and @eimearekenny.bsky.social as the GRC chairs 👀

Links to apply below 👇

Dongwon and team are terrific!

I know many of you have been awaiting us launching transcript expression data in gnomAD. We were waiting for the GTEx v10 release which is now out so we are finally able to launch this. Enjoy!!

Prevalence and Risk Factors for Secondary Hypertension in Young Adults | Hypertension BACKGROUND: The prevalence of secondary causes of hypertension in young adults is unknown, and therefore, there is no consensus about the indication of screening of secondary hypertension (2HTN) in th...

Age 18-40, nearly 1/3 with hypertension had a form of secondary hypertension, of which renovascular hypertension was the etiology in 18.4%

www.ahajournals.org/doi/10.1161/...

Terrific to see your and @pdmace2.bsky.social patient support activities and all the engagement - great work!

Outstanding presentation by @santhikganesh.bsky.social to our UH Harrington HVI and FMDSA virtual support group: What the patient should know about FMD/SCAD genetics. Able to host 250 people from around the world. I appreciate her making complex genetic concepts accessible. Pardon rough images.

Phase 1 Study of AAV9.LAMP2B Gene Therapy in Danon Disease | NEJM Danon disease is a rare, X-linked, monogenic cardiomyopathy caused by mutations in the lysosomal-associated membrane 2 gene (LAMP2), which encodes the LAMP2 protein. In male patients, the predomina...

The era of precision therapy for inherited cardiovascular disease is here. To date, we had almost nothing to offer patients with severe inherited cardiomyopathy.

We are now on the verge of a new chapter with dozens of genetic-based therapies entering clinical trials.

www.nejm.org/doi/full/10....

Report: Every dollar of NIH research funding doubles in economic returns Research funded by the National Institutes of Health (NIH) generated $2.46 in economic activity for every $1 of funding in 2023, a total of $92.9 billion, according to an

Research funded by NIH generated $2.46 in economic activity for every $1 of funding in 2023 [a total of $92.9 billion]

www.fiercebiotech.com/research/rep...

Dr. Nanette Wenger, the queen of hearts Heart disease was once considered a man's disease. Dr. Nanette Wenger changed that. But the 93-year-old cardiologist says her work is not yet done.

Dr. Wenger’s charge to the next generation of researchers in women's cardiovascular health: “Investigate, educate, advocate, and legislate”

At #AHA24, Dr. Nanette Wenger reminds us we’re all ‘standing on the shoulders of giants’ in healthcare. As we celebrate 100 years of Scientific Sessions, we honor the pioneers who paved the way and look ahead to a new century of innovation.

What a privilege to hear a talk from Dr. Bruce Beutler, Nobel Laureate, at #AHA2024 on defining innate immunity in human diseases using forward genetic approaches. Inspiring work from an incredibly accomplished physician-scientist.

Welcome to societies/journals joined 🦋👇 #AHA24 #CardioSky

ACC @accintouch.bsky.social
AHA Sciences @ahascience.bsky.social
AHA Journals @ahajournals.bsky.social
JAMA @jamacurrent.bsky.social
ASPC @aspcardio.bsky.social
Am J Prev Card @ajpcardio.bsky.social
J Card Fail @jcardfail.bsky.social

Recently back from a lovely visit @Duke to support PRVH research and patient care, at our 3rd International PRVH Symposium hosted and led by @ColemanDM_vasc. Terrific to see all the progress for this rare disease since we first convened in 2019 in Ann Arbor, MI. #PCORI #HTN #FMD
www.prvh-pcor.org

I will speak about "Genetics and Genomics of FMD and SCAD: What Patients Should Know" at the FMD and Arterial Dissection Support Group Webinar Tuesday, November 19, 2024. Look forward to updating and answering questions.

Registration link: www.fmdsa.org/fmd-and-arte....

All - Bluesky Directory A curated collection of all things relating to the Blue Sky social media platform.

Hello! Just getting set up here- this directory is helpful. blueskydirectory.com/starter-pack...