Mauro Castelló Sanjuán

Ha passat un any.

Temps insuficient per a un dol tan gran.

Hui és dia de fer memòria pels que ja no estan

i de cuidar a totes les víctimes.

Però cal recordar que s'ha de continuar lluitant,

perquè encara no s'han atés les nostres demandes:

VERITAT.

JUSTÍCIA.

REPARACIÓ.

29.10.2025 08:15 — 👍 10    🔁 3    💬 0    📌 1

4-Me working with @rubengonzalez.bsky.social. Text caption "Got to supervise my own post-doc (Rubén)"

22.10.2025 09:17 — 👍 1    🔁 0    💬 0    📌 0

2-A screenshot of my phone gallery showing all the sheets of manually recorded data. Text caption "This is a Snapshot of what my life has been"

3-The fly incubator with fly drawings all around, all customized. Text caption "Mum let me decorate my room"

22.10.2025 09:17 — 👍 1    🔁 0    💬 1    📌 0

I will think about this next time! Sorry I missed it here. Here is the description of the pics:

1- A cartoon of a sick Drosophila melanogaster, wearing a mask, and surrounded by four viruses of different colours (the viruses of the study)

22.10.2025 09:17 — 👍 1    🔁 0    💬 1    📌 0

Persistent viral infections impact key biological traits in Drosophila melanogaster Persistent viral infections in insects are not as harmless as once believed. This study reveals how such infections in fruit flies alter survival, reproduction, behavior, and gene expression, offering...

(5/5)
Thanks to all members of the @salehlabparis.bsky.social for support and teamwork; couldn't have done it without you 🫶

Thanks to @pasteur.fr for hosting me during my PhD journey😄👨‍🔬

The corrected proofs are out! Read the full article at @plosbiology.org : plos.io/4olpuXmm

17.10.2025 14:07 — 👍 9    🔁 3    💬 0    📌 0

Having shared that...

(4/5)
We found that:

*Persistence reduces fly survival

*Hosts trade reproduction for immunity

*Persistently infected flies have impaired movement and altered sleep, but keep circadian rhythm

*Different viruses trigger distinct transcriptional responses

*And more!

17.10.2025 14:07 — 👍 5    🔁 0    💬 1    📌 0

(3/5)
But first, I wanna share some sneak peeks of how this work has come to be, how I made the lab home, and the bonding that comes with working closely:

17.10.2025 14:07 — 👍 6    🔁 0    💬 1    📌 1

(2/5)
In our latest work, we established persistent viral infections to examine their impact on this model organism.
We followed survival and other life history traits, and we also performed a transcriptomic analysis over time… (The data is available for you to play with it! 💻🧬🪰)

17.10.2025 14:07 — 👍 5    🔁 0    💬 1    📌 0

I'm so excited to share this with all of you!
This is the very first paper where I am the first author 🥹
Let me share some insights about our work 👇🧵(1/5):

How do persistent viral infections impact the host?

What happens when a fly becomes persistently infected by a virus?

17.10.2025 14:07 — 👍 16    🔁 8    💬 2    📌 0

Cartoon illustration depicting a sick Drosophila melanogaster surrounded by different viruses, symbolizing the impact of persistent viral infections on the model organism. Image credit Rubén González.

Persistent viral #infections in #insects are not as harmless as once believed. @salehlabparis.bsky.social &co show how such infections in #FruitFlies alter survival, reproduction, behavior & gene expression, revealing the hidden costs of #viral persistence @plosbiology.org 🧪 plos.io/4olpuXm

13.10.2025 13:08 — 👍 40    🔁 14    💬 1    📌 2