MJ´s lab

Dysregulation of mTOR Signaling after Brain Ischemia In this review, we provide recent data on the role of mTOR kinase in the brain under physiological conditions and after damage, with a particular focus on cerebral ischemia. We cover the upstream and ...

Hi everyone!

Take a look at our review:

"Dysregulation of mTOR Signaling after Brain Ischemia"

www.mdpi.com/1422-0067/23...

Pharmacological inhibition of mTORC1 reduces neural death and damage volume after MCAO by modulating microglial reactivity - Biology Direct Ischemic stroke is a sudden and acute disease characterized by neuronal death, increment of reactive gliosis (reactive microglia and astrocytes), and a severe inflammatory process. Neuroinflammation i...

Happy to share with you our publication in Biology Direct on the use of Rapamycin as a modulator of microglial response following ischemic stroke.

Hope you find it interesting!

biologydirect.biomedcentral.com/articles/10....

The dynamics of oligodendrocyte populations following permanent ischemia promotes long-term spontaneous remyelination of damaged area Stroke is a major public health concern, with limited clinically approved interventions available to enhance sensorimotor recovery beyond reperfusion.…

Very pleased to share with you the latest publication conducted in our laboratory. It describes an endogenous mechanism of brain tissue repair mediated by oligodendrocytes following cerebral ischemia.

I hope you find it interesting!

www.sciencedirect.com/science/arti...

Glial Cells as Therapeutic Approaches in Brain Ischemia-Reperfusion Injury Ischemic stroke is the second cause of mortality and the first cause of long-term disability constituting a serious socioeconomic burden worldwide. Approved treatments include thrombectomy and rtPA in...

Hi everyone!

It is a pleasure to share with you our review:

"Glial Cells as Therapeutic Approaches in Brain Ischemia-Reperfusion Injury"

www.mdpi.com/2073-4409/10...