I have also developed novel algorithms, using opencv, for the quantification of condensates properties in microscropy pictures. Check my github for more information! github.com/mas-gu/llps_...
11.08.2025 10:14 โ ๐ 3 ๐ 1 ๐ฌ 0 ๐ 0@masgu.bsky.social
Research associate @hillerlab.bsky.social #NMR #chaperone #structuralbiology #hsp70
I have also developed novel algorithms, using opencv, for the quantification of condensates properties in microscropy pictures. Check my github for more information! github.com/mas-gu/llps_...
11.08.2025 10:14 โ ๐ 3 ๐ 1 ๐ฌ 0 ๐ 0I have created the video showcasing the PDIA6 condensate dynamics and function using Blender and the Molecular Nodes module! Visualizing science like never before. #Blender #MolecularNodes @bradyajohnston.bsky.social
11.08.2025 10:14 โ ๐ 4 ๐ 0 ๐ฌ 1 ๐ 0Our results show PDIA6 condensates recruit key chaperones (BiP, ERdj3, Grp94) to enhance proinsulin folding & prevent misfolding, driven by Caยฒโบ. This opens new perspectives for tackling protein misfolding diseases like diabetes! @natcellbio.nature.com
11.08.2025 10:14 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0Thrilled to share my first corresponding author paper as a project leader in @hillerlab.bsky.social โช Amazing work from first author @annaleder.bsky.social We discovered multi-chaperone condensates in the ER that revolutionise the current vision of protein folding!
www.nature.com/articles/s41...
Shreyan Datta has demonstrated exceptional performance in our lab. I highly recommend him to anyone seeking an outstanding PhD candidate!
30.07.2025 14:40 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0Great work from @annaleder.bsky.social in my chaperone sub-group at the Hiller Lab!
12.06.2025 12:50 โ ๐ 3 ๐ 0 ๐ฌ 0 ๐ 0Two postdoctoral positions in the group of Dr. Malene R. Jensen at the Institute for Structural Biology in Grenoble, France, protein kinase (MAPK) cell signaling pathways (incl NMR, X-ray crystallography and cryo-electron microscopy) www.jensen-nmr.fr #NMRjobs #NMRchat #NMR ๐งฒ
05.06.2025 12:46 โ ๐ 7 ๐ 2 ๐ฌ 0 ๐ 0Merci Mathieu!
05.06.2025 12:55 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0Thanks, glad you like it!
03.06.2025 07:40 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0Itโs fully adaptable to study other nucleotide-driven machines, dissecting functional cycles, regulation, and cofactor effects with unprecedented resolution. #MolecularMachine
02.06.2025 09:16 โ ๐ 2 ๐ 0 ๐ฌ 0 ๐ 0Applied to the Hsp70 BiP NBD, in-cyclo NMR reveals all 11 microscopic kinetic rates of ATP binding, hydrolysis & product release โ showing ADPยทPi release, not ATP hydrolysis, is the rate-limiting step controlling the cycle duration.
02.06.2025 09:16 โ ๐ 2 ๐ 0 ๐ฌ 1 ๐ 0Thrilled to share our new method in-cyclo NMR that lets us watch molecular machines in action โ decoding molecular machine kinetics with atomic precision and exceptional time resolution in one go! ๐ Check it out: doi.org/10.1038/s414... #NMR #StructuralBiology
02.06.2025 09:16 โ ๐ 23 ๐ 5 ๐ฌ 4 ๐ 0Great to be back at the @enc-conference.org #ENCISMAR2025 . Enjoying the conference and the beautiful wildlife.
06.04.2025 21:46 โ ๐ 4 ๐ 0 ๐ฌ 0 ๐ 0