Guillaume Mas's Avatar

Guillaume Mas

@masgu.bsky.social

Research associate @hillerlab.bsky.social #NMR #chaperone #structuralbiology #hsp70

88 Followers  |  107 Following  |  12 Posts  |  Joined: 06.12.2024  |  1.8271

Latest posts by masgu.bsky.social on Bluesky

I have also developed novel algorithms, using opencv, for the quantification of condensates properties in microscropy pictures. Check my github for more information! github.com/mas-gu/llps_...

11.08.2025 10:14 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I have created the video showcasing the PDIA6 condensate dynamics and function using Blender and the Molecular Nodes module! Visualizing science like never before. #Blender #MolecularNodes @bradyajohnston.bsky.social

11.08.2025 10:14 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Our results show PDIA6 condensates recruit key chaperones (BiP, ERdj3, Grp94) to enhance proinsulin folding & prevent misfolding, driven by Caยฒโบ. This opens new perspectives for tackling protein misfolding diseases like diabetes! @natcellbio.nature.com

11.08.2025 10:14 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Thrilled to share my first corresponding author paper as a project leader in @hillerlab.bsky.social โ€ช Amazing work from first author @annaleder.bsky.social We discovered multi-chaperone condensates in the ER that revolutionise the current vision of protein folding!
www.nature.com/articles/s41...

11.08.2025 10:14 โ€” ๐Ÿ‘ 19    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Shreyan Datta has demonstrated exceptional performance in our lab. I highly recommend him to anyone seeking an outstanding PhD candidate!

30.07.2025 14:40 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Great work from @annaleder.bsky.social in my chaperone sub-group at the Hiller Lab!

12.06.2025 12:50 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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> Malene R. Jensen @ IBS Grenoble Research team of CNRS research director Malene Ringkjรธbing Jensen at the Institut de Biologie Structurale, Grenoble, France

Two postdoctoral positions in the group of Dr. Malene R. Jensen at the Institute for Structural Biology in Grenoble, France, protein kinase (MAPK) cell signaling pathways (incl NMR, X-ray crystallography and cryo-electron microscopy) www.jensen-nmr.fr #NMRjobs #NMRchat #NMR ๐Ÿงฒ

05.06.2025 12:46 โ€” ๐Ÿ‘ 7    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Merci Mathieu!

05.06.2025 12:55 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Thanks, glad you like it!

03.06.2025 07:40 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Itโ€™s fully adaptable to study other nucleotide-driven machines, dissecting functional cycles, regulation, and cofactor effects with unprecedented resolution. #MolecularMachine

02.06.2025 09:16 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Applied to the Hsp70 BiP NBD, in-cyclo NMR reveals all 11 microscopic kinetic rates of ATP binding, hydrolysis & product release โ€” showing ADPยทPi release, not ATP hydrolysis, is the rate-limiting step controlling the cycle duration.

02.06.2025 09:16 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Thrilled to share our new method in-cyclo NMR that lets us watch molecular machines in action โ€” decoding molecular machine kinetics with atomic precision and exceptional time resolution in one go! ๐Ÿš€ Check it out: doi.org/10.1038/s414... #NMR #StructuralBiology

02.06.2025 09:16 โ€” ๐Ÿ‘ 23    ๐Ÿ” 5    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 0

Great to be back at the @enc-conference.org #ENCISMAR2025 . Enjoying the conference and the beautiful wildlife.

06.04.2025 21:46 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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