MS Bioworks

The Complex by Blue Man Group
Intact by Au Pairs
Other science puns....

Desert Island Discs - Professor Dame Carol Robinson, scientist - BBC Sounds Dame Carol Robinson, scientist, shares the soundtrack of her life with Lauren Laverne.

Carol Robinson on Desert Island Discs - have a listen friends: www.bbc.co.uk/sounds/play/...
An inspirational scientist & friend. An example of combining scientific excellence, courage, hard work and really importantly; kindness. (Yes I’m biased, but it’s true nevertheless)
@kavlioxford.bsky.social

Jennifer Doudna is named 2026 Priestley Medalist The award recognizes the biochemist for discoveries on ribozyme function and CRISPR gene editing, and international science leadership

@acs.org is recognizing Jennifer A. Doudna with the Priestley Medal for her discoveries on ribozyme function, the Dicer RNase enzyme, double-stranded RNA processing, and CRISPR gene editing, along with her impactful international science leadership. cen.acs.org/people/award... #chemsky 🧪

Group Leader – Molecular Systems Biology Unit Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...

Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!

Analytical development and application of a targeted liquid chromatography-tandem mass spectrometry assay for chimeric aducanumab A sensitive and specific liquid chromatography-tandem mass spectrometry assay was developed for the quantification of chimeric aducanumab (chAdu), a therapeutic antibody targeting pathological amyl...

Success! We've now run almost 2000 mouse cortex and plasma samples through this assay so expect more publications referencing it very soon. Much thanks to the Skyline team and @maccoss.bsky.social #modelad #teammassspec #proteomics www.tandfonline.com/doi/full/10....

a man is holding a guitar in front of a microphone and looking at the camera . ALT: a man is holding a guitar in front of a microphone and looking at the camera .

RIP OZZY

YouTube video by Chroma Context Rot: How Increasing Input Tokens Impacts LLM Performance

If you learn one thing about LLMs this week it should be this:
youtu.be/TUjQuC4ugak?...

What does it mean? Try, you're not wave, you're a graph database. #AI #LLM

Wow Rob, come for the finance, stay for the romance!

Benchmarking the AI-based diagnostic potential of plasma proteomics for neurodegenerative disease in 17,170 people Co-pathology is a common feature of neurodegenerative diseases that complicates diagnosis, treatment and clinical management. However, sensitive, specific and scalable biomarkers for in vivo pathologi...

Can AI reveal risk & co-pathology of multiple neurodegenerative diseases from a single blood sample? We explored AI-based diagnostic power on high rank plasma proteomics (N=17,170). www.medrxiv.org/content/10.1... #neuroskyence #neurosky #Alzheimer #compneuro #AI #datascience #neurology

What's the purpose of the model? If all that matters is the sequence then it doesn't matter, but if your looking at some property of the peptide that could be biased by the presence of the mod then you would at least want to see a +/- result.

Eighteen million years of diverse enamel proteomes from the East African Rift - Nature The isolation of dental proteins from fossils deposited 1.5 million to 18 million years ago in the Turkana Basin in Kenya, a tropical region, demonstrate the promise of dental enamel for palaeoproteom...

It’s finally out! 18 million year old enamel proteins from the Turkana Basin, Kenya @paleoproteomicist.bsky.social #paleoproteomics #proteomics 🧪 ⚒️

www.nature.com/articles/s41...

Dude, send him to Wholefoods. You can literally dump anything there and they return it for you.

Microscoop is live in Nijmegen!
A big thank you to the Roepman Lab and the Syncell team for an exciting and productive week of installation, training, and scientific exchange!
From biovalidation to imaging and seminar discussions, the enthusiasm was contagious.
#Microscoop

Imputation versus integrating noise and calling it an identification. Binary differences don't have to be a bad thing.

See also

www.science.org/doi/10.1126/...

For folks wondering where the hot #proteomics is happening send your CV to Monte Rosa Therapeutics. Lots of cool stuff going on there

cen.acs.org/pharmaceutic...

Stopped in to see a friend and see if he was having any fireworks for the 4th of July... that would be a yes #Merica #4thofJuly Happy Independence Day folks!

A transformer model for de novo sequencing of data-independent acquisition mass spectrometry data - Nature Methods Cascadia is a mass spectrometry-based de novo sequencing model that uses a transformer architecture to handle data-independent acquisition data and achieves substantially improved performance across a...

If you asked me 5 years ago if it would be possible to use a de novo tool on DIA data, I would have thought it would only exist in science fiction. Love being proved wrong. Great work from Justin Sanders. #proteomics #massspectrometry
www.nature.com/articles/s41...

Diagram of Mascot DIA: Mascot Distiller processes DIA runs into peak lists and detects precursor masses in MS1 and MS2 scans; these are sent to Mascot Server for database searching; finally, Distiller downloads the PSMs and performs MS1 quantitation.

We are working on Mascot DIA, which is a universal spectrum-centric solution for DIA analysis. What is spectrum-centric searching meant to solve? Find out in our blog:

www.matrixscience.com/blog/the-pro...

#proteomics #massspec

ChatGPT?

Over the past 5 years, everyone on our team has played an important role in our mission. The brilliant minds on Team #Syncell have been instrumental in shaping the future of next generation #proteomics. Thank you for joining us on this journey. Can’t wait for the next 5 years! 🥳

New release! MaxQuant 2.7.0 & Perseus 2.1.5 introduce metadata tools that enhance both public data reusability and personal research workflows:
- Export metadata as SDRF
- Annotate output tables with SDRF
Tutorial: bit.ly/3TO9GyV
Preprint: bit.ly/4eMwqt3
#TeamMassSpec

Syncell is #hiring! Want to join a team of innovators that is shaping the future of next-generation #proteomics?
We're searching for:
⭐️ Sr Product Marketing Manger
⭐️ Sr Territory Sales Executive - EMEA
⭐️Inside Sales/Lead Generation Specialist
www.syncell.com/careers/

24TB wow!

You need a good size SSD, 4TB, as a working drive. You can back that up to a mechanical in the same machine. 256GB of RAM doesn't do any harm. GPU? Maybe to future proof.

⏳ Last chance to register!
Discover how Dr. Cristiana Lungu uses optoproteomics and a two-photon laser to reveal spatial insights into epigenetic misregulation in cancer cells.
Want to explore chromatin biology with subcellular precision? Don’t miss it. ow.ly/LFuV50W4v41

Pumped to finally show off our spatial proteomics work presented a few weeks ago at the EAS Congress @eassociety.bsky.social and now live on @biorxivpreprint.bsky.social 🥳

Time for a science thread! #TeamMassSpec #SpatialProteomics #AtheroSky 🧵

www.biorxiv.org/content/10.1...

Hey Team Proteomics.

New release of MetaMorpheus now natively supports Bruker .d files for DDA PASEF.

Also now supporting .msalign as inputs.

get your copy free now while they last:
github.com/smith-chem-w...

Illumina to acquire SomaLogic, accelerating its proteomics business and advancing the company's multiomics strategy Illumina, Inc. (NASDAQ: ILMN) announced today it has entered into a definitive agreement with Standard BioTools (NASDAQ: LAB) under which Illumina will acquire SomaLogic, a leader in data-driven prote...

Big news in Proteomics this morning. Illumina acquiring Somalogic. #Proteomics

finance.yahoo.com/news/illumin...