Jase Gehring's Avatar

Jase Gehring

@skyjase.bsky.social

scientist at UC Berkeley inventing advanced genomic technologies lover of molecules, user of computers https://scholar.google.com/citations?user=63ZRebIAAAAJ&hl=en

713 Followers  |  1,377 Following  |  1,777 Posts  |  Joined: 03.10.2023  |  2.1948

Latest posts by skyjase.bsky.social on Bluesky

Many such cases

07.02.2026 17:40 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

We could have a space elevator before the decade is out, but chemists decided it wasn’t worth it to share their raw data + metadata in machine readable format

07.02.2026 17:25 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

custom tailored lab coat. gigaflex. necktie always looks good under a lab coat. this man has fucked around and he is about to find out in the best way

07.02.2026 17:01 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

you think LLMs have powerful world models? no. no man has handwriting this good, and piss-scribbling of this quality is simply out of the question. a truly intelligent system would know that

07.02.2026 16:58 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

why has machine learning been so much more successful in biology than chemistry? because biologists, in the face of staggering complexity, made their data publicly available and machine readable. chemists, meanwhile, decided a PDF of an NMR trace was good enough. a costly mistake for humanity

07.02.2026 16:54 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Super important structure. Congrats and thanks

07.02.2026 16:46 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Gonna assume this is just a joke

07.02.2026 14:58 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

very interesting. i've had similar success with misdirection in bio domain. i'm not making unsafe requests, just bypassing overly stringent safety filters. this legitimately unsafe request takes it to another level

06.02.2026 22:03 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

any excuse to use the glass cutter! i cut them in thirds and THEN i need to etch the backside πŸ—‘οΈ

06.02.2026 21:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

mmhmm ya i'm doing surface modifications and it's kinda nice. i also like to etch or notch corners for the same purpose. any excuse to use my glass cutter πŸ—‘οΈ

06.02.2026 20:25 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

that's the transition i'm talking about. our industry is already heavily automated, and there are lots of places LLMs can fill in an reduce human intervention. i think it will be a surprisingly smooth progression as we are able to offload more of the scientific cycle to AI

06.02.2026 18:33 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Hey Nick! Hope all is well with you and the escalante crew!! πŸš€

06.02.2026 17:44 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
glass slide with G L O B E printed on top, "unmod" written on bottom in scientist scrawl

glass slide with G L O B E printed on top, "unmod" written on bottom in scientist scrawl

how do we feel about glass slides with a manufacturer's logo on?

06.02.2026 17:11 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

big implications for open models. most users will be able to do a ton of useful work with just local inference

06.02.2026 16:51 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

i often get lost in the drudgery of labwork when really i'm using so many skills that are still uniquely human. for full automation, we need systems that combine LLM, world model, real-time visual motor integration, and fine dexterity. i'm angling to start working on this transition

06.02.2026 16:24 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Still only ~5% of the NIH annual budget, but overall China is on an incredible scientific trajectory.

06.02.2026 14:26 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

it is direct but also pretty dishonest and/or misleading!

05.02.2026 02:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Same. would be awesome to have direct integration with a vision/language model! someone probably has this going with local inference already

03.02.2026 23:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Ya or preview or something. I don’t think it’s available to me and I’m tired of navigating their mess to find out. very Google problems

03.02.2026 19:46 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I get Gemini from work and I’ve been waiting to use G3 in the CLI but it’s been two months and it’s still not available. Huge waste of time setting up a google cloud project

03.02.2026 18:02 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

It can really code. Feel like they’re just behind on the harness

03.02.2026 17:59 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

β€˜Sticks’ β€˜By Element’ FTW

03.02.2026 17:57 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

The world would be a better place if everyone used this representation of DNA at all times

03.02.2026 17:54 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

If and only if!

03.02.2026 16:19 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I’ve transitioned to using LLMs as interfaces to other tools. LLM +codebase, +docs, +software, +web search. Massive increase in utility over a chatbot

The base LLM without context has many issues. An LLM with appropriate context and guidance is much more powerful

03.02.2026 13:26 β€” πŸ‘ 11    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

β€œWell, look, I’ll never say no, and we will always investigate any evidence of misconduct, BUT…”

- Todd Blanche, Deputy AG

03.02.2026 12:38 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Tech companies insisting β€œthere is no bottom.” regulators urging β€œkeep looking”

03.02.2026 12:30 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

It’s better because when the work is done there is just more work but when the agent framework is done there is … ah, no, still more work

03.02.2026 12:18 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Wait I think this is a great candidate for natural language interface! CAD/Blender too!

03.02.2026 12:16 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

Something I’ve often thought about but never really learned about. Will read with interest!

02.02.2026 23:04 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

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