Ivana Gasic

Thanks Manuel! I hope you enjoy the read 😉

Lab’s 2nd story aired today!
Fantastic @ac-almeida.bsky.social cracks the cellular function of tubulin autoregulation - an over four decades old enigma!
Read on to learn how she deployed human 3D cell culture models to link tubulin homeostasis to tissue organization & viability. Bravo Ana! 👏🏻🍾

Spatio-temporal control of mitosis using light via a Plk1 inhibitor caged for activity and cellular permeability - Nature Communications Light is a powerful tool for controlling biological processes. Here, the authors demonstrate its use to modulate inhibitor activity and diffusion, enabling precise control of cell division in multicel...

Arresting mitosis with visible light! Brilliant Victoria von Glasenapp from the Gotta and Winssinger labs @UNIGE develops a cool photo-caged PLK1 inhibitor, which we deploy in 3D spheroids to control mitosis with exquisite spatio-temporal precision. Check out the original article: lnkd.in/eTnzy5Nc

When you come out of your midterm evaluation and your amazing team surprises you with these beauties 😍💐! Thank you, the ProMiCe team, for these flowers, support, and the brilliant work you are doing 🥰🙏!

Soluble αβ-tubulins reversibly sequester TTC5 to regulate tubulin mRNA decay - Nature Communications When tubulin proteins are present in excess, their encoding mRNAs are selectively degraded in a process initiated by the protein TTC5. Here, the authors show that tubulins themselves reversibly seques...

Hello Bluesky community! What a better way to introduce myself and my research team than post our lab’s first paper freshly off press 🥳🍾

We reveal how tubulins regulate the stability of their mRNA via reversible sequestration of TTC5. Bravo A. Batiuk and all coauthors 👏🏻🥂

doi.org/10.1038/s414...