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Davit Potoyan

@potoyan.bsky.social

We are a curiosity-driven theoretical/computational biophysics lab at Iowa State University. Interested in biomolecular condensates, allostery, gene regulatory networks, chromatin, the origin of life, and RNA functions

240 Followers  |  163 Following  |  3 Posts  |  Joined: 25.11.2024  |  1.679

Latest posts by potoyan.bsky.social on Bluesky

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Our RNA condensate work is finally out! Using simulations, we uncover the origin of the lower critical solution temperature (LCST) behaviour underlying thermo, iono-sensing functions in pure RNA condensates. www.pnas.org/doi/10.1073/...

04.11.2025 19:09 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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A new paper shows how LCD sequence patterns encode condensate dynamics and material properties.
πŸ”Ή Periodic repeats β†’ Elasticity-dominated
πŸ”Ή Disordered sequences β†’ Viscosity-dominated
πŸ”Ή Minimum sticker spacing is crucial for fluidity, preventing transitions to glassy states.
doi.org/10.1371/jour...

24.02.2025 01:38 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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In collaboration with @priya-r-banerjee.bsky.social we dive a little deeper into the microscopic interactions and sequence patterns that are shaping condensate activation energies pubs.acs.org/doi/10.1021/... For more context see also our prior work www.science.org/doi/10.1126/...

06.12.2024 14:22 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

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