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Stephen McLaughlin

@lmbbiophysics.bsky.social

Biophysics@MRC Laboratory Molecular Biology, Cambridge All opinions are my own

426 Followers  |  556 Following  |  13 Posts  |  Joined: 30.10.2023  |  1.989

Latest posts by lmbbiophysics.bsky.social on Bluesky

HMS - Postdoctoral Fellow in BCMP, Brown Lab We invite applicants for a postdoctoral fellow position in the Brown lab at Harvard Medical School in Boston, Massachusetts. The Brown lab uses structural, biophysical, and biochemical approaches to d...

Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526

18.11.2025 20:05 โ€” ๐Ÿ‘ 19    ๐Ÿ” 19    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the โ€šwoman in CryoEMโ€˜ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...

18.11.2025 10:18 โ€” ๐Ÿ‘ 51    ๐Ÿ” 40    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Join the LMB's PhD programme!
Applications now open for October 2026
Deadline 2nd December 2025

Join the LMB's PhD programme! Applications now open for October 2026 Deadline 2nd December 2025

Want to join the LMB as a PhD student in October 2026?
Youโ€™ve got two weeks left to apply!
Visit our website for more details: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd December 2025.

18.11.2025 14:28 โ€” ๐Ÿ‘ 6    ๐Ÿ” 12    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks to the speakers and all who attended our Next Generation Biophysics Symposium. We now looking forward to the 10th Symposium on 16th September 2026. Here is a link to catch up on what happened in this year's

14.11.2025 15:18 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Assembly, architecture and functional roles of microbial surface layers - Nature Reviews Microbiology Surface layers (S-layers) are ubiquitous protein assemblies that coat prokaryotic cells, with their functional roles increasingly coming into focus. In this Review, Isbilir and colleagues discuss rece...

Assembly, architecture and functional roles of microbial surface layers

Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kรผgelgen and @vikramalva.bsky.social.

S-layers are everywhere!

www.nature.com/articles/s41...

13.11.2025 20:13 โ€” ๐Ÿ‘ 85    ๐Ÿ” 31    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 6
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Excellent #postdoc opportunity available in @sjorsscheres.bsky.socialโ€™ group, working on new image processing algorithms for #cryoEM structure determination in their #RELION open-source software.
www.nature.com/naturecareer...
Apply by 25 NOV
#PostdocJobs #ScienceJobs

06.11.2025 15:46 โ€” ๐Ÿ‘ 27    ๐Ÿ” 23    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Our lab @mrclmb.bsky.social in Cambridge is seeking a passionate PhD student to explore transcription-coupled splicing! Join our team for an exciting project to understand human gene regulation ๐Ÿงฌ Feel free to get in touch directly #PhD #cryoEM #biochemistry

www2.mrc-lmb.cam.ac.uk/students/int...

23.10.2025 10:32 โ€” ๐Ÿ‘ 10    ๐Ÿ” 11    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Biological Laboratory | LEGOยฎ Ideas This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publโ€ฆ

I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. ๐Ÿค—
beta.ideas.lego.com/product-idea...

16.10.2025 08:07 โ€” ๐Ÿ‘ 117    ๐Ÿ” 64    ๐Ÿ’ฌ 7    ๐Ÿ“Œ 7
Join the LMB's PhD programme!
Applications now open for October 2026
Deadline 2nd December 2025

Join the LMB's PhD programme! Applications now open for October 2026 Deadline 2nd December 2025

Considering a PhD in molecular biology?
Make sure to check out the projects on offer at the LMB!
www2.mrc-lmb.cam.ac.uk/students/int...
General applications by 2nd DEC.
US Gates Scholarship applications by 15th OCT.
#PhD

03.10.2025 09:19 โ€” ๐Ÿ‘ 8    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Is that a pointer, looks more like a jedi sword!

10.09.2025 14:17 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Excited that we are only two weeks away for our Next Generation Biophysics Symposium 2025. We have a fantastic line-up of speakers. Registration is closing soon. Come in person or view on-line
#Biophysics #SingleMolecule #CryoEM #nmr #proteindynamics

19.08.2025 12:29 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0
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Desert Island Discs - Professor Dame Carol Robinson, scientist - BBC Sounds Dame Carol Robinson, scientist, shares the soundtrack of her life with Lauren Laverne.

Carol Robinson on Desert Island Discs - have a listen friends: www.bbc.co.uk/sounds/play/...
An inspirational scientist & friend. An example of combining scientific excellence, courage, hard work and really importantly; kindness. (Yes Iโ€™m biased, but itโ€™s true nevertheless)
@kavlioxford.bsky.social

10.08.2025 10:40 โ€” ๐Ÿ‘ 12    ๐Ÿ” 7    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Cryo-EM structure of the vault from human brain reveals symmetry mismatch at its caps Lรถvestam and Scheres present a cryo-EM structure of vault particles, found during tau filament extraction from progressive supranuclear palsy (PSP) brain tissue. They reveal a symmetry shift at the va...

Sofia Lรถvestam's vault structure is now online in Structure @cellpress.bsky.social. ๐Ÿฅณ

How beautifully explorative is #cryoEM! We never planned to do this. The vaults just came down with #amyloids from human brain tissue, and Sofia decided to have a closer look.

www.cell.com/structure/fu...

12.08.2025 16:05 โ€” ๐Ÿ‘ 125    ๐Ÿ” 29    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0
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Research Group Leader in Chemical/Synthetic Biology at MRC Laboratory of Molecular Biology Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...

We are looking to recruit a tenure track group leader in the field of Chemical/Synthetic Biology (in the broadest sense) to lead a research program within the Division of Protein & Nucleic Acid Chemistry ( www.jobs.ac.uk/job/DNW809/r... ) at the MRC Laboratory of Molecular Biology (LMB).

14.07.2025 12:09 โ€” ๐Ÿ‘ 27    ๐Ÿ” 33    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 4
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Postdoctoral Fellow - Costa Lab Salary for this Role: From ยฃ45,500 with benefits, subject to skills and experience. Job Title: Postdoctoral Fellow - Costa Lab Reports to: Alessandro Costa Closing Date: 03/Aug/2025 23.59 GMT Job Desc...

Less than two weeks left to apply!

Postdoc positions in my lab to study

1. initiation of DNA replication.

2. chromatin replication/epigenetic inheritance.

Great for biochemists, biophysicists & structural biologists.

Deadline 3 August 2025.

crick.wd3.myworkdayjobs.com/External/job...

21.07.2025 14:57 โ€” ๐Ÿ‘ 25    ๐Ÿ” 31    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
AstraZeneca, MRC Laboratory of Molecular Biology, Imperial College London, MRC Laboratory of Medical Sciences
Next Generation Biophysics Symposium 2025
Wednesday 3rd September 2025
Hybrid Symposium (Zoom & MRC LMB, Cambridge)
Keynote Speaker: Professor Cees Dekker
Registration open

AstraZeneca, MRC Laboratory of Molecular Biology, Imperial College London, MRC Laboratory of Medical Sciences Next Generation Biophysics Symposium 2025 Wednesday 3rd September 2025 Hybrid Symposium (Zoom & MRC LMB, Cambridge) Keynote Speaker: Professor Cees Dekker Registration open

Want to hear from experts about how new and emerging technologies can be harnessed to answer complex biological questions?
Donโ€™t mis the 2025 Next Generation Biophysics Symposium on Wednesday 3rd September!
Find out more details and register here: www3.mrc-lmb.cam.ac.uk/sites/nextgen/

15.07.2025 11:22 โ€” ๐Ÿ‘ 5    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Highly collaborative efforts that involved 6 lab members and the labs of @yiliangding.bsky.social and @rdaslab.bsky.social. We uncovered a telomerase dimer and its potential role in telomere maintenance.

11.07.2025 10:22 โ€” ๐Ÿ‘ 59    ๐Ÿ” 17    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Great opportunity for a Research Support Officer to join @cellbiol-mrclmb.bsky.social, supporting @deriverylab.bsky.social in their studies of the molecular mechanisms behind receptor sorting in endosomes.
More info: www.nature.com/naturecareer...
Apply by 10 JUL
#ScienceJobs

23.06.2025 15:11 โ€” ๐Ÿ‘ 17    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg  and Julie

A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg and Julie

๐Ÿšจ JOB ALERT ๐Ÿšจ
We're hiring a Research Assistant โ€“ no PhD needed!
Join us to explore the molecular mechanisms of receptor sorting in endosomes.
Experience in protein expression/purification, cloning & cell culture desired ๐Ÿงซ๐Ÿ”ฌ
Apply now ๐Ÿ‘‰ www.nature.com/naturecareer...

#STEMCareers #ResearchJobs

23.06.2025 13:00 โ€” ๐Ÿ‘ 49    ๐Ÿ” 32    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 5
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Excited for our program of speakers at Next Generation Biophysics 2025. Come join us as registration is now open either in person or online:
www3.mrc-lmb.cam.ac.uk/sites/nextge...

20.06.2025 13:34 โ€” ๐Ÿ‘ 8    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Measurements of molecular size and shape on a chip Size and shape are critical discriminators between molecular species and states. We describe a microchip-based high-throughput imaging approach offering rapid and precise determination of molecular pr...

Madhavi Krishnans lab with an absolutely amazing new measurement technique:
Measurements of molecular size and shape on a chip | Science www.science.org/doi/10.1126/...

09.05.2025 08:12 โ€” ๐Ÿ‘ 37    ๐Ÿ” 10    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
Schematic illustrating the structural changes undergone by MukBEF SMC complex during DNA capture and ingestion.

Schematic illustrating the structural changes undergone by MukBEF SMC complex during DNA capture and ingestion.

How do SMC complexes capture DNA? ๐Ÿงช

Led by Frank Bรผrmann, Jan Lรถweโ€™s & Mark Dillinghamโ€™s groups have identified the directional loading mechanism the bacterial SMC complex MukBEF uses to capture & ingest DNA, & found a phage inhibitor to this pathway.

Read more: tinyurl.com/4s8nrrkk

#LMBResearch

31.03.2025 14:40 โ€” ๐Ÿ‘ 68    ๐Ÿ” 36    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2

Great opportunity in a fantastic lab

14.03.2025 15:49 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Structural mechanism of LINE-1 target-primed reverse transcription Long interspersed element-1 (LINE-1) retrotransposons are the only active autonomous transposable elements in humans. They propagate by reverse transcribing their mRNA into new genomic locations by a ...

Excited to share our latest work, led by the incredible @automnenine.bsky.social (now an Ass. Prof. at Princeton)! We uncover key insights into the retrotransposition mechanisms of LINE-1 ORF2p, the enzyme responsible for writing a significant portion of our genome.
www.science.org/doi/10.1126/...

06.03.2025 21:33 โ€” ๐Ÿ‘ 112    ๐Ÿ” 38    ๐Ÿ’ฌ 8    ๐Ÿ“Œ 3
Kelly Nguyen

Kelly Nguyen

Our latest โ€˜Cell Scientist to Watchโ€™ interview is with Kelly Nguyen @kellythd-nguyen.bsky.social @mrclmb.bsky.social. We learn about Kellyโ€™s career, her advice on collaborative research and her passion for martial arts.
journals.biologists.com/jcs/article/...

10.02.2025 12:25 โ€” ๐Ÿ‘ 37    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Ingo Greger sat in front of a computer screen displaying an AMPA Receptor structure

Ingo Greger sat in front of a computer screen displaying an AMPA Receptor structure

Great position for a postdoc to join @igreger.bsky.socialโ€™s group in the LMBโ€™s Neurobiology Division, using diverse methods to study synaptic AMPA glutamate receptors.
Read more about the job here: www.nature.com/naturecareer...
Apply by 20 FEB
#PostdocJobs #ScienceJobs

03.02.2025 09:48 โ€” ๐Ÿ‘ 7    ๐Ÿ” 11    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Rising Talent Fellowship - MRC Laboratory of Molecular Biology RISING TALENT FELLOWSHIP The MRC Laboratory of Molecular Biology (LMB) is proud to launch the next application round of its three-year fully funded

The @mrclmb.bsky.social believes in the benefits of a diverse workforce, and is proud of its history in training next-gen scientists. Three-year postdoc fellowships are now available for those who self-identify as being from a (mixed) Black heritage background.
www2.mrc-lmb.cam.ac.uk/recruitment/...

29.01.2025 09:07 โ€” ๐Ÿ‘ 25    ๐Ÿ” 16    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

We (Tim Coulson & Syma Khalid) are launching a new science podcast. We will discuss recently published work of world leading scientists in an accessible and non-technical style. Topics will include, AI, search for alien life, latest treatments for diseases, quantum computers, science of football.

26.01.2025 18:49 โ€” ๐Ÿ‘ 31    ๐Ÿ” 12    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 4
Apply now!
LMB Rising Talent Fellowship
3-year postdoctoral fellowship for Black heritage scientists
Visit www.mrc-lmb.cam.ac.uk for more information

Apply now! LMB Rising Talent Fellowship 3-year postdoctoral fellowship for Black heritage scientists Visit www.mrc-lmb.cam.ac.uk for more information

The LMB Rising Talent Fellowship for Black heritage scientists is open for applicants!
With this 3 year postdoc position we want to enable scientists of Black heritage to learn & grow their experience.
To apply and for full details check here: www2.mrc-lmb.cam.ac.uk/recruitment/...โ€ฏ
Please share!

23.01.2025 12:19 โ€” ๐Ÿ‘ 18    ๐Ÿ” 35    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
John Sutherland

John Sutherland


Congratulations to John Sutherland, Group Leader in the LMBโ€™s PNAC Division, who has received the Award in Early Earth and Life Sciences โ€“ Stanley Miller Medal from @nasonline.org for his work investigating the chemical origins of life on Earth.

www2.mrc-lmb.cam.ac.uk/john-sutherl...

#LMBNews

23.01.2025 16:05 โ€” ๐Ÿ‘ 7    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@lmbbiophysics is following 20 prominent accounts