If you're into neurodevelopment, neural function and behaviour, this is a fantastic opportunity grounded in solid, impactful previous work!

🚨 We’re looking for a PhD student! 🧠🪰
Join the Münch Lab at @jlugiessen.bsky.social to study how neural circuits turn sensory input into behavior.

We use #Drosophila, combining:
🔬 Imaging
🧬 Neurogenetics
🐝 Behavior

👉 bit.ly/drosophd
🌍 munchlab.org

Feel free to share!

#PhD #neuroscience #job

#Drosophila @flybase.bsky.social requires emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to #FlyBase, and in the worst case scenario access to the website will also be lost". Please help if you can!

If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social

Last few days to apply!
Post-doctoral position 3 years Wellcome funded in UK
To investigate how experience shapes the brain
Drosophila neurogenetics, imaging, behaviour
Deadline 19/3/25
Pls RP.
#drosophila
#postdoc
#jobs
Apply here

edzz.fa.em3.oraclecloud.com/hcmUI/Candid...

And none of this (with more to come this year! :)) would be possible without the awesome support of Fondation Bettencourt Schueller!

There has never been a better time to study neural circuit development! Are you passionate about the mechanisms underlying wiring specificity? We have exciting projects in the pipeline and are looking for talented colleagues to join our team! Drop me a line if you’re interested!

Thanks to our reviewers whose input helped us significantly improve the manuscript, and to @cellpress.bsky.social for the great experience with the Cell Press Multi-Journal Submission!

Synaptic promiscuity in brain development Precise synaptic connectivity is a prerequisite for the function of neural circuits, yet individual neurons, taken out of their developmental context, readily form unspecific synapses. How does the ge...

In this context, biased adjacency is a contributor in the developmental timeline of synaptic specificity by bringing together the right neurons at the right time and location, thereby restricting partner availability before synaptogenesis. pmc.ncbi.nlm.nih.gov/articles/PMC...

Given neurons’ intrinsic drive to form synapses, perhaps the establishment of synaptic specificity is best understood as a continuous process of developmental choices where neurons are prevented from connecting with the wrong partners.

Instead, they contribute to synaptic specificity by biasing cellular adjacency—causing neurons to segregate into discrete physical domains and restricting partner availability before synaptogenesis.

We demonstrate that receptor-ligand pairs of the Beat and Side families of cell adhesion molecules, expressed between synaptic partners, are not required for synapse formation.

We now provide a mechanistic understanding of how these interactions shape neural circuit formation, linking these molecules to the cellular interactions they support.

Brain wiring determinants uncovered by integrating connectomes and transcriptomes Yoo et al. combine synaptic connectome, single-cell transcriptome, and protein interactome maps to identify brain wiring determinants in the Drosophila visual system. Matching expression of Side-II/Be...

Our study follows Yoo et al. www.cell.com/current-biol..., which first showed that Beat/Side, cell surface adhesion molecules, contribute to synaptic specificity—helping neurons form precise connections with the right partners

In this work, we studied how neurons are organized into layers during development and how this process influences the connections (synapses) they form with each other.

Biased cell adhesion organizes the Drosophila visual motion integration circuit Layer-specific brain computations depend on neurons synapsing with specific partners in distinct laminae. In the Drosophila lobula plate, axons of the…

Thrilled to share our lab's first manuscript—now in print! 🎉 This was a true team effort led by two outstanding scientists, Yannick Carrier and Laura Quintana Rio.
www.sciencedirect.com/science/arti....

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