Campàs Lab

🎉 After a two-year break, #PoLDay returned stronger than ever! Over 160 members from our community came together for a full day of interdisciplinary talks, research posters, team building games and more.🌟Thank you to all the organizers!

Read the event recap in our PoL news⬇️
tud.link/ca72se

Congrats Jesse! Very well deserved :)

It was great to have you as colleague at @poldresden.bsky.social ! I know you will do great science also at @mbisg.bsky.social. Probably we will continue to “work” together through the PoL-MBI partnership. See you soon either in Dresden or Singapore! :) Good luck with everything!

Anthony A. Hyman will become EMBL’s next Director General.

He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999.

www.embl.org/news/people-...

Green Card Interviews End in Handcuffs for Spouses of U.S. Citizens

I need everybody to read this and understand what’s going on. These are spouses of US citizens in the country legally. They have entry clearance and green cards, they’ve passed background checks and have no criminal records. ICE is taking them anyway.

Gift link:

www.nytimes.com/2025/11/26/u...

No problem with uploading. Downloading is the issue.

So slow that it effectively does not ever load for me… that is too bad

Is it just me or the new security verification step in @biorxivpreprint.bsky.social has rendered it so slow that effectively does not work anymore? Does anyone else have the same problem?

Congratulations Elias!

Congratulations!

@campaslab.bsky.social @jesseveenvliet.bsky.social labs use #gastruloids to explore axial extension in mammalian embryos
www.biorxiv.org/content/10.1...
They find novel mechanisms involving and interplay of proliferation and mechanical constraining.
#NotInTheGenes #CellsRUs

#IZFS is proud to announce Drs. Antonia Monteiro and Rong Li as our #SCZI2026 Keynote Speakers! We are honored to have them join us in Singapore to present on their science. See below for their presentation information, and a link to our program! www.izfs.org/education/11...

YouTube video by PBS NewsHour Top researchers consider leaving U.S. amid funding cuts: 'The science world is ending'

The United States was the leading destination for top scientists from all over the world.

That is ending. Politicians ended it. It will cripple our future competitiveness.

And it’s such a bitter tragedy. Almost no Americans, Conservative or Liberal, grasp what is now being stolen from them.

Merci Bertrand! We see it on the surface of the tailbud and PSM. It goes doen in the somites, likely because of inverse polarity…

Thanks André! Marc worked relentlessly… indeed a lot of work

Thank you :)

📣 New preprint! Stoked to share a fantastic collaboration with @campaslab.bsky.social!

We discover a unique mammalian mechanism for body axis elongation using mouse and human gastruloids, and confirm central findings in mouse embryos.

Check out the 🧵 👇

@mpi-cbg.de @poldresden.bsky.social

Gracias campeon 😊

You look very young 😂

Btw, this is precisely the reason to use gastruloids. We first did the mouse gastruloids, then compared to in vivo in mouse, then human gastruloids. I think that in human it is as close as possible to we can get today...

In human it is nearly impossible because of obvious reasons…

Impossible is nothing 😉 It is just very very difficult at the moment

Muchas gracias, Elias!

Really happy and proud to share my PhD work! This has been a fun and collaborative project that led to the discovery of a unique biophysical mechanism of axial elongation in mouse gastruloids and human gastruloids, and confirmed our key findings in vivo with mouse embryos. Check it out down below!

I want to finish by thanking Jesse @jesseveenvliet.bsky.social, his lab and my lab and Heidi and @ellensletten.bsky.social, for the outstanding and fun collaboration! It has been a blast! 😃 This is to many more to come 🍾🥂

Altogether, our data points to a shared physical mechanism of posterior body axis elongation unique to mammals, different from other vertebrate species!

Is this mechanism happening in vivo? We checked whether the key features of this physical mechanism of elongation, uniform cell proliferation and a posterior actin cap, are present in mouse embryos. And it seems they do!

In a nutshell, the tissue expansion caused by cell proliferation is mechanically constrained by a supracellular actin cap that redirects the forces and guides axis elongation!

We used laser ablation to check if the bulk tissue underneath would expand when we ablate the surface actin… and it does in the posterior region where there is an actin cap! But not in the anterior side

We found a supracellular actin accumulation at the tissue surface only on the posterior half of the gastruloid - a posterior actin cap. But, does this cap mechanically constrain expansion?