Baptiste Lacoste

Wow can’t wait to read! Congrats!

Wrapping up my visit to UVA, had a great time and learned about a lot of exciting stuff! Thanks @eyolab.bsky.social for hosting me!

Bien connus

Je vois que ton passage à Bordeaux a porté ses fruits! J’imagine que le 🍷 a aidé 😇

Professional advice: when celebrating your 10th year lab anniversary🍻, bring your trainees to an axe throwing club, so they can release all the anger accumulated. Let them imaging your face is on the wall 😂

NMDA receptors coordinate brain vascular development via neuron-to-endothelial tip cell crosstalk in zebrafish - Nature Communications Neurovascular interaction is critical for normal brain vascular development. Here, the authors show that neuronal NMDARs regulate brain vascular development via VEGF-induced global Ca2+ activities of ...

Cool neurovascular paper in #zebrafish #cerebrovascular #development

New findings suggesting that PROX1 compromises BBB integrity by negatively regulating BBB-associated Wnt signaling. #BBB #BloodBrainBarrier #cerebrovascular

“Elon Musk is part of the administration” that says it all… I feel sorry for all my friends south the Canadian border

Canada Impact+ Research Chairs - Multiple Disciplines Posting Reason: New Position Job Family: Academic Leadership and Faculty Union affiliation: APUO Faculty/Department: Research Management Services Campus: Main Campus Date Posted (YYYY/MM/DD): 2025/12/...

uottawa.wd3.myworkdayjobs.com/en-US/uOttaw...

There are two award values (based on achievements/seniority): $1M per year or $500,000 per year for eight years, with the possibility for a four-year extension at 50% of the initial award value per year.
For the uOttawa submission, the portal has been greatly simplified.

We actively encouraging top-quality international candidates to apply. The Impact+ program emphasizes research excellence in areas of Canada's strategic priorities, and significant potential to move research discoveries into tangible economic and social benefits.

The University of Ottawa is recruiting international talent through a special program named "Canada Impact+ Research Chairs". See link at the very bottom.

🚨 Recruitment alert ! If you consider having made significant research & training contributions abroad and wish to come to Canada, please submit your application by January 17th ! The University of Ottawa is recruiting international talent through a special program. See thread below.

🎉 New Publication in @pnas.org

Excited to share our lab’s latest research article: PIP₂ Corrects an Endothelial Piezo1 Channelopathy
pnas.org/doi/abs/10.1... (Open Access)

Nuno Loureiro, professor and director of MIT’s Plasma Science and Fusion Center, dies at 47 Nuno Loureiro, an MIT professor of nuclear science and engineering and of physics, has died at 47. A theoretical physicist and fusion scientist, and director of the MIT Plasma Science and Fusion Cente...

On his way to bring « the dream of clean, near-limitless fusion power closer to reality », Nuno Loureiro was shot at his home. A brilliant mind, husband, father and mentor is gone.

thanks Ciaran!

Metabolic, epigenetic and transcriptomic alterations in postnatal 16p11.2 deficient murine astrocytes Autism Spectrum Disorders (ASD) are associated with metabolic dysregulation. While astrocytes are integral to cerebral metabolism, their molecular and functional changes in ASD are poorly known. Using...

New preprint from the lab! For those who love astrocytes 🤩. We welcome feedback! #preprint #openaccess #astrocytes #autism

Happy holidays and best wishes from our lab!

Pervasive neurovascular dysfunction in the ventromedial prefrontal cortex of female depressed suicides with a history of childhood abuse - Molecular Psychiatry Molecular Psychiatry - Pervasive neurovascular dysfunction in the ventromedial prefrontal cortex of female depressed suicides with a history of childhood abuse

A beautiful paper from my friend @naguibmechawar.bsky.social's team ! www.nature.com/articles/s41... #cerebrovascular

They were all placed to protect Trump…

PDGFRα is required for postnatal cerebral perivascular fibroblast development Perivascular fibroblasts (PVFs) are a cell type associated with large diameter blood vessels in the brain and spinal cord parenchyma and leptomeninges…

PDGFRα is required for postnatal cerebral perivascular fibroblast development. Congrats @siegenthalerlab.bsky.social ! #cerebrovascular #fibroblasts #development

Excited to share the latest from our lab (final version, open access):

Brain Capillary Ion Channels: Physiology and Channelopathies

Physiology | @apspublications.bsky.social

journals.physiology.org/doi/full/10....

@uvmlarnermed.bsky.social

Great shot! I need to seriously update mine as well (to the risk of scaring people away 😂)

Or course, that’s why now he is in favour

Hypertension-induced neurovascular and cognitive dysfunction at single-cell resolution Hypertension is a leading cause of cognitive impairment, attributed to cerebrovascular insufficiency, blood-brain barrier disruption, and white matter…

Hypertension-induced neurovascular and cognitive dysfunction at single-cell resolution @cp-neuron.bsky.social #cerebrovascular #hypertension

Dynamic modulation of the blood–brain barrier in the healthy brain - Nature Reviews Neuroscience The blood–brain barrier was conventionally seen as a static protective structure, but a more complex, dynamic view of this barrier has now emerged. In this Review, Friedman et al. discuss the dynamic ...

Excellent new review on the blood-brain barrier, by Alon Friedman and colleague @natureportfolio.nature.com #Cerebrovascular #BloodBrainBarrier

The sad reality of humankind forgetting about history….

The brain neurovascular epigenome and its association with dementia Ziegler et al. reveal distinct genetic and epigenetic mechanisms underlying Alzheimer’s disease and cerebral small vessel disease within neurovascular cells, identifying immune-related AD risk and bro...

The brain neurovascular epigenome and its association with dementia. #cerebrovascular #epigenetics

Imagine!

Dream house! With the dome 🤩