Skeletal editing: How close are we to true cut-and-paste chemistry?
Reactions that alter organic scaffolds by a single atom are already proving useful, but time will tell if theyโll fundamentally change how molecules are made
Less than a decade ago, reactions for adding, deleting, and swapping single atoms in complex organic molecules were almost unheard of. Now thereโs a growing community of researchers working on them. cen.acs.org/synthesis/Sk... #chemsky ๐งช
12.07.2025 12:32 โ ๐ 40 ๐ 11 ๐ฌ 2 ๐ 1
I've had @danielsattler.bsky.social's mock apple pie.. It's great, even tough there is nothing resembling apples in the recipe.
05.07.2025 21:39 โ ๐ 3 ๐ 0 ๐ฌ 0 ๐ 0
Degradative Alcohol Functionalization by Titanocene Photocatalysis
Organotitanium complexes are scarcely employed in photocatalytic reactions despite their robust ligand-to-metal charge-transfer photo-chemistry. Herein, we describe the development of titanocene pho-t...
Great paper here on @chemrxiv.bsky.social from the Lipschultz lab @jeflip.bsky.social - 1st author J. Shah just gave a super talk on this Ti-cat dehydroxylation work at our ACS Conn. Valley Section symposium today - really neat rearrangements and compound fragmentations as synthetic strategy too
27.06.2025 17:20 โ ๐ 14 ๐ 3 ๐ฌ 1 ๐ 1
Just got back from another excellent Heterocyclic Compounds GRC and am excited to have been elected Vice-Chair. I look forward to putting together an exciting program in 2027! Happy to hear any cool ideas for session topics.
27.06.2025 19:33 โ ๐ 8 ๐ 0 ๐ฌ 0 ๐ 0
Really excited to share this work. Lots of fun and opportunities with Cp-ligated Ti complexes. Especially proud of Jagrut for spearheading our efforts when he transferred into the group in summer 2023.
11.06.2025 14:48 โ ๐ 7 ๐ 1 ๐ฌ 0 ๐ 0
speaker
This week marked the 3rd SBU-BNL Photochemistry Supergroup, with a great poster session and 10 speakers from @stonybrooku.bsky.social Chemistry & MSCE, @brookhavenlab.bsky.social @queenscollegecuny.bsky.social, @hofstrau.bsky.social, and @adelphiu.bsky.social! Thanks to SBU ORI for support!
15.05.2025 13:18 โ ๐ 3 ๐ 1 ๐ฌ 0 ๐ 0
Home | Jill Alty
I'm excited to share that I'll be joining the Chemistry Department at Stony Brook University as a tenure-track Assistant Professor this fall! My group will use fundamental organic transformations to advance polymeric biomaterials. Check out jillalty.com for more information.
28.04.2025 12:57 โ ๐ 56 ๐ 6 ๐ฌ 3 ๐ 2
Postdoctoral Associate
Click the link provided to see the complete job description.
We are looking for a new postdoc to join @lipshultzsbu.bsky.social to work on synthetic methods enabled by catalytic photochemistry of catalyst-substrate complexes! Please apply here by May 8: stonybrooku.taleo.net/careersectio... #chempostdoc
23.04.2025 13:21 โ ๐ 2 ๐ 3 ๐ฌ 0 ๐ 0
Great news: NIH postbac program is recruiting again! If your grad school plans were affected by program cutbacks or admissions freezes this year I highly encourage you to apply, this could be a perfect opportunity. Please repost.
www.training.nih.gov/research-tra...
10.04.2025 01:22 โ ๐ 211 ๐ 198 ๐ฌ 5 ๐ 1
Asymmetric Carbon Insertion!
08.04.2025 14:38 โ ๐ 23 ๐ 2 ๐ฌ 0 ๐ 0
It also involved a fun collaboration with Yuezhi Mao
that shed light on how stereochemistry was induced (spoiler alert: Dynamic Kinetic Resolution of the indole).
08.04.2025 12:22 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0
Synthesis of quinoline-3-carboxylates by a Rh(II)-catalyzed cyclopropanation-ring expansion reaction of indoles with halodiazoacetates
Beilstein Journal of Organic Chemistry
This work was led by Ryan Zanolini and Mariam Basilaia and was inspired by one of my favorite 145 year old reactions (The Ciamician-Dennstedt Rearrangement). The work builds off of some seminal work from the Bonge-Hansen group (linked below).
www.beilstein-journals.org/bjoc/article...
08.04.2025 12:08 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0
I have been fairly quiet on Bluesky, but I figured I would break the silence to share this preprint from my group. Inspired by all the great recent skeletal editing work, we developed an atropisomer selective strategy to take Indoles to quinolines.
chemrxiv.org/engage/chemr...
08.04.2025 12:01 โ ๐ 23 ๐ 0 ๐ฌ 3 ๐ 1
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024.
That's not to mention the countless lives that biomedical research has saved.
Show me a better investment than that.
www.forbes.com/sites/michae...
12.03.2025 20:47 โ ๐ 2040 ๐ 1154 ๐ฌ 23 ๐ 72
๐ A new way to celebrate in the Lipshultz Group! Our first paper warrants a sweet treat, and we've decided to make it a tradition. Here's to many more paper cakes! ๐
19.02.2025 15:50 โ ๐ 3 ๐ 1 ๐ฌ 0 ๐ 1
picture of Gustafson Group and Rotation students hard at work at the Bench at Stony Brook
I guess it's time for an actual post. Celebrating the end of my first semester at Stony Brook with post doc @grustin.bsky.social and a talented group of rotation students at the aptly named (but not chemistry themed) The Bench
11.12.2024 23:56 โ ๐ 6 ๐ 0 ๐ฌ 0 ๐ 0
Postdoctoral Associate
Click the link provided to see the complete job description.
First post and Iโm excited to connect with #chemsky! My group has a broad interest in molecular inorganic and organometallic #chemistry with a focus on developing new platforms for controlling the selectivity of (electro)catalytic reactions. We also have an open postdoc position, see ๐ for info!
20.11.2024 00:15 โ ๐ 11 ๐ 5 ๐ฌ 1 ๐ 0
Digital chemist & chemistry automation nerd | Lives in a historical canalside cottage | "Aggressively sciency" | Views are mine | She/they. Macclesfield, UK
A curated selection of out-of-context nonsense spoken and Slacked by the newsroom of scientists and science-adjacent punks at @cenmag.bsky.social.
Associate Professor of Chemistry/Biochemistry at UC Santa Cruz - organic chemistry/ biosynthesis/biocatalysis - dogs/Oilers hockey ๐จ๐ฆโก๏ธ๐บ๐ธ
Professor in biocatalysis at Jiangnan University, Wuxi, China.
Incoming Assistant Professor of Chemistry at Stony Brook University. Now: AOB Postdoc at MIT in Kiessling Group. Then: PhD at UNC in Leibfarth/Alexanian Groups.
Chemistry Ph.D. Candidate (Rice University) | SDSU Alum | Violinist | Gamer | Poetry | (He/Him)
โ๏ธ๐ป๐ฎ๐ณ๏ธโ๐
Assistant professor @rwjms.bsky.social in Biochemistry and Molecular Biology. We study proteostasis using cutting-edge genomics. serebreniklab.org
Ph.D peptide development chemist with a synthesis job. Hoping to one day grow up to be a process chemist.
Assistant Professor of Chemistry at NYU Abu Dhabi
PhD in organic chemistry, electronic music lover, amateur cook and baker. (he/him)
Senior Lecturer in Organic Chemistry at QUB. My group invent new reactions and use them to make useful molecules. Views my/our own.
https://mclaughlinresearchgroup.com/
We explore many fields of chemistry and biology (many of them concerning enzymes).
Located at McGill University, Montreal.
Student-ran account: posts not by Dr. Auclair unless indicated.
RP/follow โ endorsement.
https://www.auclair-group.mcgill.ca
4th Year DPhil Student in Organic Chemistry at the University of Oxford
Research Group in the Department of Chemistry at the National University of Singapore (NUS). Transforming chemical & carbohydrate synthesis through base metal catalysis, radical cross-coupling & molecular editing.
Molecular chemist, Current @JCC Childs postdoc fellow w/@christhechang @Princeton chemistry. PhD w/ A. Radosevich @ChemistryMIT
Temple University chemistry professor, some other stuff too.
Assistant professor of organic chemistry at Aalto University. Natural product total synthesis, theoretical chemistry, and chemistry education. He/Him.
Group website: https://etosgroup.fi/
CNRS researcher in Organic Chemistry at Aix Marseille University - France
I make Dad jokes on NPR and also write books and other things.