Gustafson Group

Reposting this. about one more week to the deadline!

Facile Trifluoromethylation of Arenes and Heterocycles via a Bench Stable Photocaged Trifluoromethylation Reagent Herein we report a simple radical aromatic trifluoromethylation process that utilizes a cationic, aromatic sulfonate ester as a trifluoromethyl radical photocage. This chemistry allows for the rapid a...

Check out our 2nd preprint of the week! It was a privilege to collaborate with @gustafsonlabsbu.bsky.social to demonstrate that our recently developed radical photocages enable quick and simple photo-induced trifluoromethylation of small molecule organics and API's.

chemrxiv.org/engage/chemr...

Check out our latests work in collaboration with @taylorlab-chembio.bsky.social! We evaluated their biomolecular photocaged trifluormethylation reagent on small molecules, finding it effected rapid trifluoromethylation of diverse aromatics, including several APIs.
chemrxiv.org/engage/chemr...

The Stony Brook Chemistry Department is searching for a Chemical Biologist at the Associate or Full professor Level. Come join us on Long Island and do some great science!
apply.interfolio.com/174211

Skeletal editing: How close are we to true cut-and-paste chemistry? Reactions that alter organic scaffolds by a single atom are already proving useful, but time will tell if they’ll fundamentally change how molecules are made

Less than a decade ago, reactions for adding, deleting, and swapping single atoms in complex organic molecules were almost unheard of. Now there’s a growing community of researchers working on them. cen.acs.org/synthesis/Sk... #chemsky 🧪

I've had @danielsattler.bsky.social's mock apple pie.. It's great, even tough there is nothing resembling apples in the recipe.

Degradative Alcohol Functionalization by Titanocene Photocatalysis Organotitanium complexes are scarcely employed in photocatalytic reactions despite their robust ligand-to-metal charge-transfer photo-chemistry. Herein, we describe the development of titanocene pho-t...

Great paper here on @chemrxiv.bsky.social from the Lipschultz lab @jeflip.bsky.social - 1st author J. Shah just gave a super talk on this Ti-cat dehydroxylation work at our ACS Conn. Valley Section symposium today - really neat rearrangements and compound fragmentations as synthetic strategy too

Just got back from another excellent Heterocyclic Compounds GRC and am excited to have been elected Vice-Chair. I look forward to putting together an exciting program in 2027! Happy to hear any cool ideas for session topics.

Really excited to share this work. Lots of fun and opportunities with Cp-ligated Ti complexes. Especially proud of Jagrut for spearheading our efforts when he transferred into the group in summer 2023.

speaker

This week marked the 3rd SBU-BNL Photochemistry Supergroup, with a great poster session and 10 speakers from @stonybrooku.bsky.social Chemistry & MSCE, @brookhavenlab.bsky.social @queenscollegecuny.bsky.social, @hofstrau.bsky.social, and @adelphiu.bsky.social! Thanks to SBU ORI for support!

I'm excited to share that I'll be joining the Chemistry Department at Stony Brook University as a tenure-track Assistant Professor this fall! My group will use fundamental organic transformations to advance polymeric biomaterials. Check out jillalty.com for more information.

We are looking for a new postdoc to join @lipshultzsbu.bsky.social to work on synthetic methods enabled by catalytic photochemistry of catalyst-substrate complexes! Please apply here by May 8: stonybrooku.taleo.net/careersectio... #chempostdoc

Great news: NIH postbac program is recruiting again! If your grad school plans were affected by program cutbacks or admissions freezes this year I highly encourage you to apply, this could be a perfect opportunity. Please repost.

www.training.nih.gov/research-tra...

Asymmetric Carbon Insertion!

It also involved a fun collaboration with Yuezhi Mao
that shed light on how stereochemistry was induced (spoiler alert: Dynamic Kinetic Resolution of the indole).

Synthesis of quinoline-3-carboxylates by a Rh(II)-catalyzed cyclopropanation-ring expansion reaction of indoles with halodiazoacetates Beilstein Journal of Organic Chemistry

This work was led by Ryan Zanolini and Mariam Basilaia and was inspired by one of my favorite 145 year old reactions (The Ciamician-Dennstedt Rearrangement). The work builds off of some seminal work from the Bonge-Hansen group (linked below).

www.beilstein-journals.org/bjoc/article...

I have been fairly quiet on Bluesky, but I figured I would break the silence to share this preprint from my group. Inspired by all the great recent skeletal editing work, we developed an atropisomer selective strategy to take Indoles to quinolines.
chemrxiv.org/engage/chemr...

NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024.

That's not to mention the countless lives that biomedical research has saved.

Show me a better investment than that.
www.forbes.com/sites/michae...

🎉 A new way to celebrate in the Lipshultz Group! Our first paper warrants a sweet treat, and we've decided to make it a tradition. Here's to many more paper cakes! 🎂

picture of Gustafson Group and Rotation students hard at work at the Bench at Stony Brook

I guess it's time for an actual post. Celebrating the end of my first semester at Stony Brook with post doc @grustin.bsky.social and a talented group of rotation students at the aptly named (but not chemistry themed) The Bench

First post and I’m excited to connect with #chemsky! My group has a broad interest in molecular inorganic and organometallic #chemistry with a focus on developing new platforms for controlling the selectivity of (electro)catalytic reactions. We also have an open postdoc position, see 👇 for info!