It's a full queue kind of day #chemsky
06.02.2026 14:06 — 👍 4 🔁 0 💬 0 📌 0
Freezer defrosting day means freezer sorting day #chemsky
22.01.2026 17:35 — 👍 1 🔁 0 💬 0 📌 0
First thiol smell of the new year. And it's not even a particularly noxious one! #chemsky
19.01.2026 16:46 — 👍 7 🔁 1 💬 2 📌 1
This is our freezer for the next few hours #chemsky
05.12.2025 18:11 — 👍 7 🔁 1 💬 1 📌 0
Come find us at @concordia.ca Loyola campus for CBGRC this Friday!
17.11.2025 15:16 — 👍 0 🔁 0 💬 0 📌 0
NEW PREPRINT:
An extensive structure-activity relationship investigation of pantetheinamides and their ability to inhibit Salmonella typhimurium.
We investigate the mechanisms of action of these compounds and their use with in vivo mouse models.
doi.org/10.1101/2025...
30.10.2025 19:54 — 👍 2 🔁 1 💬 2 📌 0
From the Auclair lab: Dr. Jacob Pierscianowski, Dr. Dustin Duncan, Dr. Blue Lan, Dr. Rohit Kholiya, Suzana Diaconescu-Grabari, Ahmed B. Abdelaal, Aracelli Chang, Shay Heans, Dr. Sanjay Campbell, Dr. Alexandre Pierret.
With collaboration from the groups of Profs. Schmeing, Findlay, and Lupien.
30.10.2025 19:54 — 👍 0 🔁 0 💬 0 📌 0
NEW PREPRINT:
An extensive structure-activity relationship investigation of pantetheinamides and their ability to inhibit Salmonella typhimurium.
We investigate the mechanisms of action of these compounds and their use with in vivo mouse models.
doi.org/10.1101/2025...
30.10.2025 19:54 — 👍 2 🔁 1 💬 2 📌 0
Here's some more balanced centrifuge arrangements #chemsky
23.10.2025 14:24 — 👍 2 🔁 0 💬 0 📌 0
We're incredibly proud to announce Dr. Jacob Pierscianowski has officially defended his PhD thesis!
Congratulations to Dr. Jake on the amazing work.
10.10.2025 18:40 — 👍 1 🔁 0 💬 0 📌 0
Good Wordle yesterday.
08.10.2025 15:38 — 👍 0 🔁 0 💬 0 📌 0
Update: purified it anyways. Fraction looks reasonably pure. Now let's see the activity tests. #chemsky
04.10.2025 22:12 — 👍 1 🔁 0 💬 0 📌 0
The Auclair Lab welcomes two new members!
Maya Gaylor, co-supervised by Prof. Lupien in Microbiology and Immunology, will be working on our antimicrobial projects.
Dr. Alana Rangaswamy is a recent graduate from the Keillor lab @uottawa.ca and will focus on enzyme and depolymerization efforts.
03.10.2025 18:10 — 👍 0 🔁 0 💬 0 📌 0
Admin got up yesterday at 7 in the morning to perform a transformation that probably didn't work. One (1) colony on the plates. This is the #chembiosky life.
23.09.2025 15:08 — 👍 1 🔁 0 💬 0 📌 1
Fun fact: we scheduled our lab cleanup day a few weeks ago, and the second we finished up, we got a notification that we were having a safety inspection the very next Monday.
Talk about good timing #chemsky
19.09.2025 22:11 — 👍 8 🔁 0 💬 0 📌 0
Many members of the Auclair lab hosted and attended the student-led Careers After Chemistry conference! #CAC2025 #chemsky
12.09.2025 20:52 — 👍 0 🔁 0 💬 0 📌 0
Literal green chemistry #chemsky
10.09.2025 17:11 — 👍 4 🔁 1 💬 0 📌 0
Doing a little setup for our new baby 👀
04.09.2025 13:23 — 👍 0 🔁 0 💬 0 📌 0
New instrument 🔜🔜🔜
03.09.2025 16:23 — 👍 0 🔁 0 💬 0 📌 0
Register | CAC 2025
Sign up for McGill Chemistry's Careers After Chemistry 2025 conference! Registration ends September 5.
cacmcgill.wixsite.com/cac2025/regi...
29.08.2025 17:58 — 👍 0 🔁 0 💬 0 📌 0
The Auclair lab went tree trekking recently! Super fun teambuilding exercise.
28.08.2025 14:34 — 👍 0 🔁 0 💬 0 📌 0
Very happy to meet 2020 Nobel Prize laureate @e-charpentier.bsky.social at @ircm.bsky.social!
20.08.2025 14:48 — 👍 2 🔁 0 💬 0 📌 0
‼️NEW PAPER ALERT
In Antimicrobial Agents and Chemotherapy, we replace an enzyme-vulnerable amide bond with a thiazole to produce potent antiplasmodial and antimalarial pantothenamide mimics. A collaboration between the Auclair lab @mcgill.ca and the Saliba lab at ANU.
doi.org/10.1128/aac....
🧵
13.08.2025 17:10 — 👍 1 🔁 1 💬 1 📌 1
Another day, another paper 😌
13.08.2025 17:13 — 👍 4 🔁 1 💬 0 📌 0
- Our pantothenamide mimics avoid degradation by pantetheinases thanks to the bond substitution
- Sub-micromolar antiplasmodial activity in vitro
- Excellent selectivity for plasmodial enzymes vs. human enzymes
- Computational analysis included to gain insight into SARs
13.08.2025 17:10 — 👍 0 🔁 0 💬 0 📌 0
Key notes:
- Made possible by Annica Chu, Dr. Mina Nekouei, Dr. Blue Lan, and Dr. Alexandre Pierret of the Auclair lab, in collaboration with Xiangning Liu from the group of Prof. Kevin J. Saliba
- These molecules follow the parasite CoA pathway and become potent, low-cytotoxicity antimetabolites
13.08.2025 17:10 — 👍 0 🔁 0 💬 1 📌 0
Professor of Biology. Ecology, evolution, genetics, in natural and urban habitats. VP of Canadian Society of Ecology and Evolution. Passionate about connecting kids with nature, advocating for grad students, postdocs, science funding. Proud Canadian!
Chemist & head of department Materials Chemistry @BAMresearch with interest in materials science 📚 & ☕️. My patronus is a double espresso. My views. She/her
A young research group at York University in Toronto. Specializing in synthesis and catalytic activation of fluorinated molecules.
http://leresearchgroup.com
Science policy reporter @cenmag.bsky.social. Based near LA. I write a lot about science funding and diversity in STEM.
Email: k_vasquez(at)acs.org
Signal: kvasquez.12
Once upon a time, I was an atmospheric chemist.
All views and opinions are mine.
Doudna Lab at UC Berkeley, Innovative Genomics Institute founder, CRISPR co-inventor and Nobel laureate innovativegenomics.org/
Concordia University, in Montreal, Canada, is North America’s top-ranked university founded in the past 50 years.
Située à Montréal, l’Université Concordia est la mieux classée en Amérique du Nord parmi celles fondées au cours des 50 dernières années.
Suivez les projets de recherche et l'activité scientifique de la Faculté des sciences! Un institut, 6 départements et les 400 scientifiques qui y enseignent.
Département des sciences biologiques
L’UQAM offre plus de 375 programmes d’études et rayonne dans de nombreux domaines de recherche et de création.
Biologist recognized worldwide for her groundbreaking work leading to the revolutionary CRISPR-Cas9 genome engineering technology.
Visit: <www.emmanuelle-charpentier.org>
Lieu de haut savoir scientifique, l’IRCM est un institut de recherche biomédicale de réputation internationale situé en plein cœur du milieu universitaire montréalais.
late to the party as always
Assistant Professor in the Dept M3 @uniofnottingham.bsky.social: Milling expert researching low carbon fuels, mechanochemistry, critical raw materials and life cycle analysis. Rocket science is simple; it's the engineering that's hard
Assistant Professor at Leiden University. Covalent inhibitors and chemoproteomics for antibiotics. Views my own. he/him/his. https://orcid.org/0000-0001-5420-4824
Big fan of total synthesis and catalysis | PhD from the Lautens group @UofT | Former undergraduate @UBC
Chemist, 🧲 spectroscopist, mother, Associate Teaching Prof. of Chemistry at University of Denver. Loves reading romance and nonfiction 💖📚, currently writing a narrative nonfiction book on spectroscopy🚨Opinions and thoughts and posts are my own!
Synthetic organic chemistry at the University of Groningen and the Stratingh Institute for Chemistry | #ChemNobel 2016 | Making smart molecules & forging stereocenters since '88
https://benferinga.com
Organic chemists that are fascinated with atropisomerism. Recently moved from SDSU to Stony Brook University.
Professor of Chemistry
University of Chicago
Single-Atom Skeletal Editing
(Interspersed with doomposting and AI skepticism)
Husband, Dad, Crossword Addict
http://levingroup.uchicago.edu
D2R | DNA to RNA is a research initiative at McGill University taking an inclusive Canadian approach to developing genomic-based #RNA therapies for rare diseases, infectious diseases and cancer.
www.mcgill.ca/dna-to-rna/
www.youtube.com/@D2RMcGill
