Takahisa Date's Avatar

Takahisa Date

@tdate.bsky.social

Postdoc in Nose lab at UTokyo | Neurobiology | Drosophila larval locomotion

9 Followers  |  30 Following  |  4 Posts  |  Joined: 23.09.2025  |  1.3518

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Thanks, Bella!

23.01.2026 12:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Wonderful collaboration between the Nose lab (UTokyo), Hiroshi Kohsaka (UEC), the Gershow lab (NYU), and the Zwart lab @maartenzwart.bsky.social (Univ. of St Andrews).

23.01.2026 03:18 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Highlights
・A02l neurons are tonically active and transiently suppressed during muscle contraction.
・EM connectomics analyses reveal that A02l neurons excite inhibitory premotor networks to maintain muscle relaxation.
・Optogenetic activation and inhibition bidirectionally change larval behavior.

23.01.2026 03:17 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Excited to share a preprint of my PhD work!
www.biorxiv.org/content/10.6...

We identified a class of segmental interneurons in the Drosophila larval VNC (the analog of the spinal cord) that gate motor output via tonic inhibition.

23.01.2026 03:13 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0

Tonically active interneurons gate motor output in Drosophila larvae https://www.biorxiv.org/content/10.64898/2026.01.19.700243v1

21.01.2026 22:15 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

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