Dr Jasleen Jolly

Characterising microstructural retinal changes in children with inherited retinal dystrophies – a retrospective observational cross-sectional study - Graefe's Archive for Clinical and Experimental Oph... Purpose Trials exploring novel treatments for inherited retinal diseases (IRDs) have utilised microstructural retinal changes for outcome measures, but such changes in children are incompletely descri...

How early can we detect retinal changes in children with inherited eye disease?

Our latest paper’s findings suggest the retina starts remodelling before symptoms appear, offering new insights into early disease stages and future treatments.

🔗 Read more: link.springer.com/article/10.1...

Dynamic neuropathophysiological changes in Charles Bonnet Syndrome: change in alpha power at the onset of a reported hallucination vision2025florence.com/abstracts/ by @jkjolly.bsky.social (in abstract book); EEG changes associated with hallucinations caused by #CBS; #neuroscience #vision2025

A group of people sitting around a table with delicious food

Great start to @arvoinfo.bsky.social 2025 meeting with the #ISCEV meeting followed by a catch up with my #unimelb colleagues. Come to my presentation on Thursday for #ClinicalTrial results.

NADSN White Paper - Inclusive STEMM Official launch of the new NADSN white paper: Towards a fully inclusive environment for disabled people in STEMM

Very excited to announce the launch of @nadsn.bsky.social white paper. Towards a fully inclusive environment for disabled people in STEMM. Please join us 31st March www.eventbrite.co.uk/e/nadsn-whit...
#NADSNWhitePaper #DisabledInSTEMM
Without inclusion the workforce is weak and science suffers

an older lady sat on a blue sofa with her daughter giving her a hug

Did you know that lifestyle and genetics can influence our chances of developing age-related macular degeneration (AMD)? Start the new year by answering five simple questions and we'll estimate your risk of AMD. Take our risk checker: https://buff.ly/3P9EKqz

In the UK disabled women are nearly twice as likely to experience sexual violence than non disabled women.

This is why I’m asking men to be aware of how they approach a situation where a disabled woman may need assistance.

Be the aware safe nice helpful dude in your approach, actions & words.

If you are a man & need to offer assistance to a blind woman just think about how you can make the situation as safe as possible.

Introduce yourself & give an immediately explanation. “Hi I’m Mike, there is a car blocking the way how can I best assist you?”

Never touch without asking.

brainlife.io: a decentralized and open-source cloud platform to support neuroscience research - Nature Methods brainlife.io is a one-stop cloud platform for data management, visualization and analysis in human neuroscience. It is web-based and provides access to a variety of tools in a reproducible and reliabl...

Discover how brainlife.io is revolutionising neuroimaging research by enhancing FAIR data practices. With tools for standardisation, visualisation, and reproducibility, this platform empowers scientists to tackle complex data pipelines with ease.
Read more: www.nature.com/articles/s41...

I am incredibly proud of Kwame Baffour-Awuah, first author on the paper. This work was inspired by the essay he entered in the Esme Umbrella's medical student essay competition. It was a pleasure to work with Kwame on this.

I am really excited to share with you our new paper! In this review we compare Charles Bonnet Syndrome to phantom limb and tinnitus syndrome, we noticed that the commonality between these conditions is a lack of sensory input.
t.co/qGkMxSZXGh

Test–retest variability of mesopic microperimetry‐associated parameters in patients with retinitis pigmentosa: REPEAT Study Report No. 2 Purpose Understanding test–retest variability (TRV) of mesopic microperimetry is critical for defining meaningful treatment effects in retinitis pigmentosa (RP) trials. This study uniquely evaluates.....

I am thrilled to share our recent publication! We examined the test–retest variability of microperimetry in patients with retinitis pigmentosa. Our study finds volume sensitivity provides spatial insights and potential as a robust endpoint.
onlinelibrary.wiley.com/doi/10.1111/...

Longitudinal assessment of structural and functional changes in rod-cone dystrophy: a 10-year follow-up study Emerging clinical trials for inherited retinal disease (IRD) require an understanding of long-term progression. This longitudinal study investigated t…

Understanding long-term progression in inherited retinal diseases is vital for successful clinical trials. Our 10-year study of rod-cone dystrophies investigated changes in retinal structure and function. Read more about our key findings here: www.sciencedirect.com/science/arti...

Our study of 432 participants provides a robust normative dataset for MAIA microperimetry and we were able to compare hill-of-vision models. Full discussion and results are available here: iovs.arvojournals.org/article.aspx...

We have developed a novel nanopore sequencing approach to measure X-inactivation skew, linking it to disease severity in X-linked retinal disorders. Read all about it in our paper here:
genome.cshlp.org/content/34/1...

Neurochemistry and functional connectivity in the brain of people with Charles Bonnet syndrome - Holly Bridge, Abigail Wyllie, Aaron Kay, Bailey Rand, Lucy Starling, Rebecca S. Millington-Truby, Willi... Background: Charles Bonnet syndrome (CBS) is a condition in which people with vision loss experience complex visual hallucinations. These complex visual halluci...

In this recent paper, we used MRI scanning to measure how the chemistry in the visual brain differs in people with Charles Bonnet syndrome and those who have sight loss but no hallucinations. See our surprising results here: journals.sagepub.com/doi/10.1177/...

Longitudinal assessment of female carriers of choroideremia using multimodal retinal imaging Background/aims Female choroideremia carriers present with a spectrum of disease severity. Unlike in men, the rate of disease progression has not been well characterised in carriers. This longitudinal...

Our longitudinal study revealed progressive retinal degeneration in female choroideremia carriers, emphasising the need for detailed multimodal imaging & functional testing in addition to retinal severity classification when assessing disease progression. bjo.bmj.com/content/earl...

Scotopic microperimetry reveals reduced rod & cone sensitivity in early choroideremia. Could this tool be key in tracking progression in clinical trials? Read our full article here: tvst.arvojournals.org/article.aspx...

Frontiers | Retinal vascular reactivity in carriers of X-linked inherited retinal disease – a study using optical coherence tomography angiography

Female carriers of X-linked inherited retinal diseases can show highly variable disease progression. We are the first to investigate vascular reactivity as a potential disease biomarker. Functional OCT-A is a useful tool to assess dynamic retinal microvascular changes.

Retinal Characteristics of Female Choroideremia Carriers: Multimodal Imaging, Microperimetry, and Genetics To describe visual function and retinal features of female carriers of choroideremia (CHM), using multimodal imaging and microperimetry.Cross-sectiona…

Female carriers of choroideremia with severe phenotypes face reduced visual function and retinal thinning. Learn how multimodal imaging and microperimetry can be used to aid detection. www.sciencedirect.com/science/arti...

Investigating the impact of asymmetric macular sensitivity on visual acuity chart reading in choroideremia Introduction Degeneration in choroideremia, unlike typical centripetal photoreceptor degenerations, is centred temporal to the fovea. Once the fovea is affected, the nasal visual field (temporal ret...

Standard VA tests may overestimate difficulties in choroideremia. In our recent paper, we highlight the need for alternatives like single-letter optotypes. onlinelibrary.wiley.com/doi/10.1111/...

96% of glaucoma patients reported comfort, and 93% rated community clinics as comparable to hospitals. A promising model, with room for enhanced patient education. Read more in our article here: bmjopen.bmj.com/content/14/1...

Optical coherence tomography in children with inherited retinal disease Recent advances have led to therapeutic options becoming available for people with inherited retinal disease. In particular, gene therapy has been shown to hold great promise for slowing vision los...

Understanding inherited retinal diseases in kids is vital for early treatment success. This review delves into #OCT findings across 8 key conditions. www.tandfonline.com/doi/full/10....

Renegotiating identity: The cognitive load of evaluating identity and self-presentation after vision loss When a person is diagnosed with a condition leading to vision loss, life cannot go on as before. As well as developing new ways to manage their daily …

A new study highlights the cognitive toll of managing identity after vision loss. Balancing past identities, disability visibility, & self-presentation choices creates a hidden cognitive burden. Read more here: www.sciencedirect.com/science/arti...

ISCEV and IPS guideline for the full-field stimulus test (FST) - Documenta Ophthalmologica The full-field stimulus test (FST) is a psychophysical technique designed for the measurement of visual function in low vision. The method involves the use of a ganzfeld stimulator, as used in routine...

It was an honour to be part of the team that was asked to create the new ISCEV and IPS guidelines for Full-Field Stimulus Testing (FST). These will promote consistency of testing and reporting, and harmonising the protocols used. See the full details here: link.springer.com/article/10.1...

Recently, I have left a toxic academic work environment and I am looking to rebuild a supportive community and my own sense of self-worth. I will be sharing some of the papers I have published in 2024.

Small white baby seal lying next to large brown mother seal on the beach. Noses are pointing to each other. Baby is 1 week old.

It was amazing to go to the rest coast of England and see baby seal pups learning to fend for themselves. They only get mothered for 3 weeks!