Dr. Peter Hall

Possible genetic clues to ME/chronic fatigue syndrome identified in massive study DNA analysis of more than 15,500 people with the debilitating condition identifies eight tentative “genetic signals”

For #ME/CFS, genomics assessed in >15,000 indviduals
with 8 genomic loci identified.
"Validation of ME/CFS as a biomedical condition and an important corrective to psychologizing ‘all in the mind’ perspectives on the disease”
www.science.org/content/arti...
www.research.ed.ac.uk/en/publicati...

Our Brain—Immune Axis Gets A Jolt Facts, data and analytics about biomedical matters

A rundown on the big advances we’re seeing on the brain-immune axis

erictopol.substack.com/p/our-braini...

I’m floored … this is pretty astounding. #SARS-CoV-2 #Covid19

Neural anticipation of virtual infection triggers an immune response - Nature Neuroscience Serino et al. show that seeing an infectious avatar approach the body in virtual reality triggers an immune response, indicating that the brain prepares the body to fight infections even for perceived...

Infection-related visual stimuli are enough to prime the immune response via the brain
#immune #brain
www.nature.com/articles/s41...

Enjoying the silence.

#summermorning #enjoythesilence #summer #nature #silhouette #sunrise

The story behind the photograph of a starving Gaza baby Photographer Ahmed al-Arini told BBC Newshour he had to catch his breath between each photograph.

www.bbc.co.uk/news/videos/...

People in Gaza are ‘walking corpses’, says Unrwa, as agency says it has 6,000 aid trucks ready to enter – Middle East crisis live Philippe Lazzarini says Unrwa findings show one in five children is malnourished in Gaza City and says agency has food and medical supplies

Oh my god, this has to stop. Let the trucks in…
www.theguardian.com/world/live/2...

Online misogyny seeping into classrooms in 'frightening' ways, teachers and experts say | CBC News A Dalhousie researcher has found misogynistic comments from students are disrupting  learning environments as teachers deal with degrading remarks and male-supremacist sentiments.

Even in post-secondary, we are seeing some highly misogynistic language popping up in online venues, with little to no moderation. Definitely not helping the situation, as it maintains an illusion of endorsement or credibility.
www.cbc.ca/news/canada/...

I was explaining to my Ukrainian colleague the phrase ‘There’s no such thing as a free lunch’. She told me the equivalent in Ukrainian is ‘The only free cheese is in the mousetrap’ - which is so much better

The mechanisms by which ultra-processed foods (UPF) drive obesity, an outstanding review article
"the evidence is sufficiently strong to justify immediate public health efforts to reduce UPF consumption."
www.nature.com/articles/s41...

A brilliant @science.org review on the brain's glymphatics, the channels for eliminating metabolic waste products, and their relationship to Alzheimer's diseases
www.science.org/doi/10.1126/...

Why happens when you put SARS-CoV-2 in with human neural (retinal) tissue in culture (organoid)?
It induces Alzheimer’s-like pathology.
www.science.org/doi/10.1126/...

A beautiful start to the day here today. Photo taken on Glastonbury Tor at sunrise.

Long COVID Rates Higher in Women: Evidence Grows New research shows long COVID strikes more women than men, illuminating more clues to how the illness works.

www.medscape.com/viewarticle/...

The lady and the rose. St Michael's tower on Glastonbury Tor.

Budapest Pride draws huge crowds in defiance of Orban legal threats - BBC News Tens of thousands have gathered for the LGBTQ march in Hungary's capital, despite a police ban and warning from PM Viktor Orban.

Budapest Pride draws huge crowds in defiance of Orban legal threats - BBC News
www.bbc.com/news/article...

There is remarkable extent of bi-directional cross-talk between the nervous system and Type 2 immunity (vs infectious parasites, allergens, irritants, and toxins). A new and superb review @sciimmunology.bsky.social
www.science.org/doi/10.1126/...

Good afternoon, Christchurch…

Things are bleak but they’re also funny. Ah, duality.

Pharmacotherapy and non-invasive neuromodulation for neuropathic pain: a systematic review and meta-analysis There remains a substantial unmet need for effective and safe treatments for neuropathic pain. The Neuropathic Pain Special Interest Group aimed to up…

Benefits of pharmacotherapy and rTMS for neuropathic pain; great review! “Pharmacotherapy and non-invasive neuromodulation for neuropathic pain: a systematic review and meta-analysis” - Lancet Neurology #pain #TMS
www.sciencedirect.com/science/arti...

Epigenetic (methylation, biological) age is associated with increased risk of dementia and brain structural changes (including atrophy). From UK Biobank's 280,000 participants, ~4,800 cases of dementia over 14-year follow-up
www.neurology.org/doi/10.1212/...

On the dysregulation of the immune system after infection resulting in #LongCovid, 2 new studies @natimmunol.bsky.social
www.nature.com/articles/s41...

Physical activity changes during midlife link to brain integrity and amyloid burden INTRODUCTION Evidence suggests that midlife physical activity may reduce Alzheimer's disease (AD) risk. In at-risk individuals, we investigated midlife physical activity changes in relation to AD-re...

A really nice study showing that increasing physical activity in midlife is associated with more favourable brain morphology indicators (medial temporal lobe) and reduced amyloid burden. #brainhealth #exercise
alz-journals.onlinelibrary.wiley.com/doi/full/10....

Honored to speak at Harvard’s Radcliffe Institute workshop on #LongCOVID. I am energized by our 2 days of brainstorming about the road ahead. The challenges are real, but I’m leaving hopeful. Millions living with Long Covid are counting on our progress—we must keep keep pushing forward!!!

A male Violet-headed Hummingbird perched at @tapirvalley.bsky.social #CostaRica

#birds #nature

The metabolic syndrome and young-onset dementia, from a nationwide cohort of ~2 million people
www.neurology.org/doi/abs/10.1...

Adherence to life’s essential 8 is associated with delayed white matter aging Adherence to LE8 is associated with delayed brain ageing, with genetic factors such as APOE4 potentially moderating this effect in specific age and sex groups. The overall benefit from a healthier lif...

Delayed brain aging associated with adherence to lifestyle and health risk factors www.thelancet.com/journals/ebi...

Risk of Dementia in Individuals With ED Visits or Hospitalizations Due to Cannabis This cohort study uses Ontario health administrative data to assess the association between cannabis-related acute care encounters and dementia diagnosis.

Hospitalization due to cannabis use associated with 23% increased risk of dementia diagnosis within the 5 years following (nb even worse for hospitalizations due to alcohol however).
jamanetwork.com/journals/jam...

"Even if we have AGI today, we have years of trying to figure out how to integrate it into our existing human world."
Great piece by Ethan with a memorable quote by Tyler Cowen!

Understanding the sport viewership experience using functional near-infrared spectroscopy - Scientific Reports Scientific Reports - Understanding the sport viewership experience using functional near-infrared spectroscopy

Just in time for the playoff season: Can brain activity signal interest in a sport when viewing a game in real time? Yes, but depends on the type of gameplay event being viewed. Hint: it’s not scoring chances.. #NHL #hockey #brain
@thehockeynews.bsky.social
www.nature.com/articles/s41...