Hi! Tse4's action is a great blueprint for new antimicrobials. It makes ion channels to couple membrane depolarization with lethal K+
efflux. This synergizes with other effectors, suggesting a powerful strategy for new combination therapies to fight resistance.
29.09.2025 20:42 — 👍 1 🔁 0 💬 1 📌 0
Thrilled to share that two of our papers with @jrpenades.bsky.social & GoogleDeepMind
are now out in @cellpress.bsky.social
1️⃣Microbial piracy: tinyurl.com/yvf6t3b3
2️⃣AI co-scientist mirrors experimental science: tinyurl.com/2dym92kj
@imperialcollegeldn.bsky.social
@imperiallifesci.bsky.social
09.09.2025 15:06 — 👍 15 🔁 7 💬 0 📌 2
A bit late but it has been a fantastic ETOX25 conference organized by @pbernalt6ss.bsky.social and @davidalbesa.bsky.social A fantastic opportunity for @casandratan.bsky.social from @fillouxlab.bsky.social to attend and to reunite a whole crew of Imperial College London Alumni.
04.08.2025 13:39 — 👍 8 🔁 2 💬 0 📌 0
Albesa Lab – Structural Microbiology Laboratory
📢 Job alert! The Structural Microbiology Laboratory (albesalab.org) has two new openings! We are looking for a PhD student and a Research Technician to join our team.
Project: "Structure-function studies of Type VI secretion system toxins".
www.biofisika.org/en/join-us
Apply before 30th September
07.08.2025 08:03 — 👍 3 🔁 7 💬 0 📌 0
Last week was a fantastic opportunity for @lucasceseti.bsky.social to share his work on Xanthomonas and Dicty at #ETOX25 🦠
The Basque Country was the place to hear great science on toxins🤩
08.07.2025 14:56 — 👍 8 🔁 4 💬 0 📌 1
We absolutely had a great time discussing about toxins, effectors and secretion systems. It's amazing how life always finds a way to overcome obstacles. Thank you @pbernalt6ss.bsky.social and @davidalbesa.bsky.social for organising and giving us the opportunity to share our work!
09.07.2025 07:44 — 👍 11 🔁 3 💬 0 📌 0
The cryo-EM structure of an adaptor-effector complex reveals the mechanism of a widespread pore-forming toxin family https://www.biorxiv.org/content/10.1101/2025.07.04.663240v1
07.07.2025 20:17 — 👍 4 🔁 1 💬 0 📌 1
A massive thank you to all the incredible participants and speakers who made ETOX 2025 in the Basque Country an unforgettable event! Your insights, discussions, and passion for bacterial protein toxins have truly advanced the field. We're already looking forward to next time! #ETOX2025
06.07.2025 18:30 — 👍 19 🔁 10 💬 0 📌 2
Check out our latest preprint! We show that the same antibacterial toxin requires different immunity proteins depending whether it’s intra or extracellular
01.06.2025 07:37 — 👍 60 🔁 31 💬 3 📌 0
@pbernalt6ss.bsky.social and @davidalbesa.bsky.social opening #ETOX2025. Looking forward to some hot science in the next couple of days.
29.06.2025 17:10 — 👍 9 🔁 2 💬 1 📌 0
It’s been a pleasure to attend and present my research at #ETOX2025! It’s amazing to see all the exciting science happening in the field!
03.07.2025 16:01 — 👍 10 🔁 2 💬 0 📌 0
#ETOX2025
02.07.2025 12:55 — 👍 8 🔁 4 💬 0 📌 0
View across the valley from Arantzazulab
Horses grazing
Sanctuary of Arantzazu
Alter inside Sanctuary of Arantzazu
#etox25 great conference and fabulous location!
30.06.2025 14:25 — 👍 12 🔁 3 💬 0 📌 0
New research reveals the mode of action of the Pseudomonas aeruginosa #T6SS Tse4 toxin. Tse4 forms ion-selective, voltage-sensitive channels in bacterial membranes, coupling cell depolarization with K⁺ efflux. This highlights a key antibacterial strategy. #PFPsky
doi.org/10.1371/jour...
06.06.2025 21:49 — 👍 36 🔁 9 💬 2 📌 3
Carme Rovira research group of computational enzymology.
https://sites.google.com/site/roviralab
https://www.icrea.cat/community/icreas/17551/carme-rovira-virgili/
Microbes & mucus 🤩 | Gut Microbial Ecology | Wageningen University, NL
Assistant professor interested in all things cell envelope. Wellcome CDA fellow. University of Warwick. https://webby-lab.owlstown.net
Structural Microbiologist studies molecular details of C. difficile at Newcastle University, UK. (she/her) Interested in science, politics, theatre, and so much more. Views my own. https://salgadolab.org/
#MSCA Postdoctoral Fellow at CIC bioGUNE (Bilbao, Spain) || Host-microbe interactions || Fungal Immunology || Innate immune memory || Trained immunity || Immunometabolism || Microbiota
#SinCienciaNoHayFuturo #MycoSky
https://linktr.ee/aizepellonrodriguez
Microbiology editor at a multidisciplinary open-access journal.
Born & raised in Asturias, Spain.
In the UK since 2008.
Dad ×3, husband ×1.
Posts in English and Spanish.
LinkedIn: http://bit.ly/CesarSanchez
The views expressed are my own.
Pues eso.
Bethesda Declaration Signer.
Postdoctoral Fellow at the NIH.
NIH Fellows United/UAW 2750 Steward.
All opinions are my own.
PhD student in the Roe lab.
Interested in pathogenic E. coli, toxins and compound discovery 🧫 Based at @uofglasgow.bsky.social
Postdoctoral fellow | Villa lab | UCSD | Genomics | Emerging Scientist and Photographer | 🌱🪴🪻😍🤟🏼 |
Microbiologist 🧫 with a huge passion for small bugs. Lost pieces of her heart in multiple locations around the globe.
A PhD student in the Cascales lab
Senior postdoctoral research scientist at ETH Zürich. Microbiology, bacterial pathogenesis, host-pathogen interactions, antibiotic persistence, pathogen transmission. Aussie 🇦🇺 expat in Switzerland 🇨🇭. Formerly University of Melbourne.
Immunologist curious about viruses, cancer, evolution and all things human
Likes all #systems thinking and still working out all the #omics 🤓
#immunosky #medsky #idsky
PhD student in Enninga lab, Institut Pasteur. Shigella, microscopy and cytoskeleton 🦠🔬🧫
scientist, immunologist who is into bacterial toxins and osteoclasts. passionate teacher, mother of three and other things....
Research Fellow at Northumbria University: phage, synthetic biology, sialic acid, transport proteins. He/him.
Professor at Montpellier University, IHPE Lab, France.
http://ihpe.univ-perp.fr/ihpe-charriere-guillaume/
Curious and interested in many aspects of phagocyte biology, vibrios, amoebae, oysters, host-pathogen co-evolution, and comparative immunology.
Postdoc at the Dunn School (University of Oxford) researching how Salmonella evades the Immune system
