Hallou Lab

Connections between physics and metabolism in brain functions Human metabolism; Cell biology; Biophysics

Delighted to share my last paper published in iScience @cp-iscience.bsky.social on the 'Connections between physics and metabolism in brain functions':

www.cell.com/iscience/ful...

Many congratulations @evapillai.bsky.social 👏😀!!

Beautiful and important study from @franzelab.bsky.social showing how Piezo1 controls not only axon guidance but also brain mechanical properties via cell-cell adhesion 👇!!

Many congratulations @evapillai.bsky.social, @sudimukherjee.bsky.social and to all authors 👏🎉😀!

It was fun to write this with the other speakers of the great (eponymous!) symposium organised by Professor Fanny Mochel (Institut du Cerveau – Paris Brain Institute) and Professor Angela Garcia-Cazorla Cazorla (Barcelona Children's Hospital Sant Joan de Déu)!

In this perspective, we discuss the connections between mechanobiology and metabolism, and how innovative approaches, such as spatial mechano-transcriptomics, can provide new insights on the physiopathology of inherited metabolic disorders.

Connections between physics and metabolism in brain functions Human metabolism; Cell biology; Biophysics

Delighted to share my last paper published in iScience @cp-iscience.bsky.social on the 'Connections between physics and metabolism in brain functions':

www.cell.com/iscience/ful...

Absolutely delighted to be hosting Dr Mo Lotfollahi from the Wellcome Sanger Institute (@sangerinstitute.bsky.social) for our next external seminar at the Kennedy Institute of Rheumatology University of Oxford (@ox.ac.uk)!

Please join us in person if you are in Oxford on Monday 👇

Absolutely delighted to be hosting Dr Mo Lotfollahi from the Wellcome Sanger Institute (@sangerinstitute.bsky.social) for our next external seminar at the Kennedy Institute of Rheumatology University of Oxford (@ox.ac.uk)!

Please join us in person if you are in Oxford on Monday 👇

Postdocs wanted - Please spread the word! We are looking for one bioinformatician and 1-2 cell biologists with different expertise! See the job ad below for more information and links to the job descriptions!

@marineluciano.bsky.social recreates intestinal Villi geometry by growing epithelial cells on wavy rolling substrates. Unexpected intrication of curvature effects is observed. Thanks to all! @caterinatomba.bsky.social @sgabriele.bsky.social @sciencesunige.bsky.social
www.biorxiv.org/content/10.6...

💡 Have you ever wondered how #circulating #tumor cells squeeze through narrow #capillaries during hashtag#metastasis ?

💥 We did, check out our latest publication just out #NatureMaterials: rdcu.be/eZHxJ

Enjoyed “A dominant character”, @samanthsubramanian.bsky.social’s biography of JBS Haldane which is also - perhaps mostly - a love letter to the scientific mindset. “To be open to the unknown strangeness of the world”

Cellular Interfaces reloaded: Join us for the @sfb1348.bsky.social International Meeting on „Mechanochemical signals at cellular interfaces" in Münster from May 27–29, 2026.
Registration opens in February! Limited spots – first come, first serve! More info: tinyurl.com/ypyzd23w
@uni-muenster.de

Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de

Congratulations to Byung Ho for spearheading this work and our HFSP team!
Curious about the formation of networks of thin lumens and some physics behind it? Take a look at the paper.

Byung Ho is looking for PI positions and he has amazing ideas and leadership.

www.nature.com/articles/s41...

Biophysics of organoids In this review, Weichselberger, Moore et al. discuss how physics-based approaches illuminate organoid development and homeostasis by integrating mechanical, chemical, and informational processes. They...

Interested in the biophysics of organoids? We just published a review in Dev Cell—take a look! dlvr.it/TPyTb8 #Organoids #Biophysics

Background of DNA strand with logos of King's College London and the Leverhulme Trust and text 21 January 2026 Robustness of morphogenesis via mechano-chemical feedbacks Professor Edouard Hannezo Institute of Science and Technology Austria (ISTA) Force Talks Mechanics of Life Leverhulme DSP seminar series

Join our next #ForceTalk with Prof Edouard Hannezo @ehannezo.bsky.social of @istaresearch.bsky.social on "Robustness of morphogenesis via mechano-chemical feedbacks"

🗓️ 21 January 2026
🕒 15:00 - 16:00 GMT

Online & open to all 👉 www.kcl.ac.uk/events/force...

#mechanobiology @kingsnmes.bsky.social

If you are considering where to publish new research on extracellular/non-autonomous/geometric/physical cause and effect in development, consider our @dev-journal.bsky.social special issue, with @rashmi-priya.bsky.social!

Contextualizing TH17 cells in cancer - Nature Reviews Immunology T helper 17 (TH17) cells can have both pro-tumour and antitumour effects. Understanding how they are regulated by environmental and regulatory cues according to context will inform strategies to harne...

New year, new paper! Thrilled to share that our review “Contextualising TH17 cells in cancer” is out now!

Congratulations to Declan & team for a fantastic, in depth overview🥳

Go give it a read here:
doi.org/10.1038/s415...

@natrevimmunol.nature.com
@kiroxford.bsky.social

And here is the link to access the whole pdf. Enjoy!

I strongly believe that focusing on information & computation during Development provides an important framework, that encapsulates the genetic, chemistry & mechanics, but focusses on organisation, dynamics & logic.
PDF: tinyurl.com/4hn34t8w

Hi @maikbischoff.bsky.social ! Can you please add me. Many thanks 😀!

How does signalling control cortical tension?

Using optogenetics and AFM, we show that myosin recruitment and cortical tension increase proportionally with RhoA signalling.

More here:
www.biorxiv.org/content/10.6...

Super work by Pierre Bohec with Guillaume Salbreux and @dianakhorom.bsky.social

Awesome opportunity to figure out the role of cytoplasmic bridges in choanos (or mESCs, if you're into those things somehow)

Beautiful study 🤩! Many congratulations @nmoris.bsky.social and to all authors 👏 🎉!!

Great quote
Waddington
Seen @DBT_inStem
#Embryo #CellsRUs #NotInTheGenes

Researchers win prestigious Kennedy Trust grant awards Two Kennedy researchers have been awarded highly competitive Kennedy Trust Transition Fellowships, supporting their journey towards independent research leadership, and another receiving a Research Ig...

Absolutely delighted to share that I have been awarded a Kennedy Trust Research Ignition Award with my colleague Dr Ruby Peters from Sheffield to develop a new label-free/AI-driven method for measuring tissue stiffness as a diagnostic and prognostic tool !! 🧬🔬💻⚙️

www.kennedy.ox.ac.uk/news/researc...

Many thanks Berta 😊!

Many thanks Diana 😀! I hope all is well for you!

Researchers win prestigious Kennedy Trust grant awards Two Kennedy researchers have been awarded highly competitive Kennedy Trust Transition Fellowships, supporting their journey towards independent research leadership, and another receiving a Research Ig...

Absolutely delighted to share that I have been awarded a Kennedy Trust Research Ignition Award with my colleague Dr Ruby Peters from Sheffield to develop a new label-free/AI-driven method for measuring tissue stiffness as a diagnostic and prognostic tool !! 🧬🔬💻⚙️

www.kennedy.ox.ac.uk/news/researc...

Of course, home made, with chunky bits of pickles and onion👌😉!!