#symbiosky

Heritable symbiont producing nonribosomal peptide confers extreme heat sensitivity and antifungal protection on its host | PNAS Insects frequently form associations with maternally transmitted symbiotic bacteria. This transmission mode ensures that symbiont-conferred effects...

It turns out, this symbiotic bacterium highly expresses a horizontally acquired NRPS operon, resulting in the production of a small, antifungal molecule.

Grateful to have worked on a fun project with @nancy-moran.bsky.social

The results are a bit more complicated:
www.pnas.org/doi/10.1073/...

Heritable symbiont producing nonribosomal peptide confers extreme heat sensitivity and antifungal protection on its host | PNAS Insects frequently form associations with maternally transmitted symbiotic bacteria. This transmission mode ensures that symbiont-conferred effects...

Super excited to share the results of one of my favorite projects, out now in PNAS! We uncovered the mechanism of protection against fungal pathogens in the aphid-Fukatsuia symbiosis. (1/2)

www.pnas.org/doi/10.1073/...