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Department for Cell and Developmental Biology, MedUni Vienna

@celldevbiomuw.bsky.social

News from the Department of Cell and Developmental Biology @meduniwien.ac.at

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Latest posts by celldevbiomuw.bsky.social on Bluesky

Impaired Autophagic Flux in Skeletal Muscle of Plectin‐Related Epidermolysis Bullosa Simplex With Muscular Dystrophy You have to enable JavaScript in your browser's settings in order to use the eReader.

🚨New publication from the Winter Lab!

Published in the Journal of Cachexia, Sarcopenia and Muscle (JCSM), this study demonstrates that the protein aggregation pathology characteristic of EBS-MD is linked to impaired autophagic flux.

🔗 onlinelibrary.wiley.com/doi/epdf/10....

17.07.2025 12:26 — 👍 2    🔁 0    💬 0    📌 0
Biallelic NSUN3 Variants Cause Diverse Phenotypic Spectrum Disease: From Isolated Optic Atrophy to Severe Early-Onset Mitochondrial Disorder | IOVS | ARVO Journals

🧬 The Bittner/Schmidt lab contributed to a study by Patrick Yu-Wai-Man et. al. in @arvoiovs.bsky.social, describing new cases of biallelic NSUN3 variants, linked to mitochondrial disorders, by disrupting mt-tRNAMet methylation and mitochondrial translation.
🔗 iovs.arvojournals.org/article.aspx...

12.06.2025 20:40 — 👍 2    🔁 0    💬 0    📌 0
Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis | Journal of Experimental Medicine | Rockefeller University Press In this study, Gawish et al. show that RNA editing of the actin cross-linker FLNA is similarly regulated in mice and humans and that the targeted induction

📢 New publication from the Vesely group in @jem.org!
Led by Riem Gawish, this study shows that edited Filamin A in myeloid cells can protect mice from chemically induced colitis.
Congratulations to all involved in this exciting collaborative work!

🧬 👉 rupress.org/jem/article/...

08.06.2025 06:13 — 👍 3    🔁 1    💬 0    📌 0
Copy Number Determination of Sperm-Borne Small RNAs Implied in the Intergenerational Inheritance of Metabolic Syndromes. A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms

📝News from the Schaefer Lab!
Sperm carry far fewer small RNAs than typically used in injection experiments. ⚠️This study quantifies them for the first time - raising important questions about how we model RNA-based inheritance.
🔗 doi.org/10.1261/rna....

04.06.2025 20:38 — 👍 5    🔁 0    💬 1    📌 0

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