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@ipbstoulouse.bsky.social

Better understanding towards better therapeutics in #Cancer, #Infection and #Inflammation (@cnrs.bsky.social et Université de Toulouse) in #Toulouse https://www.ipbs.fr

615 Followers  |  261 Following  |  69 Posts  |  Joined: 12.11.2024  |  1.7756

Latest posts by ipbstoulouse.bsky.social on Bluesky

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Membrane-associated effluxosomes coordinate multi-metal resistance in Mycobacterium tuberculosis - The EMBO Journal Bacterial pathogens must withstand metal-induced stress during infection, yet the mechanisms by which they sense and respond to toxic metal ions remain incompletely understood. Here, we uncover a prev...

How can bacterial pathogens weather metal ion stress during infection?
@pierredupuy.bsky.social, @oneyrolles.bsky.social et al implicate ‘effluxosomes’, membrane clusters of metal-binding chaperones & exporters coordinating M. tuberculosis resistance to toxic metals
link.springer.com/article/10.1...

13.02.2026 12:09 — 👍 8    🔁 5    💬 1    📌 0
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Tuberculose : comment la bactérie évacue les métaux toxiques pour résister au système immunitaire Le bacille de la tuberculose survit dans les cellules immunitaires en neutralisant des métaux toxiques comme le zinc.

#ResultatScientifique🔎| La bactérie responsable de la tuberculose est capable d'évacuer les métaux toxiques pour résister au système immunitaire

✍️ @oneyrolles.bsky.social
🤝 @ipbstoulouse.bsky.social
📕 buff.ly/4R5iaMB
▶️

13.02.2026 15:00 — 👍 10    🔁 8    💬 0    📌 0
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🥳 𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐥𝐚𝐭𝐞𝐬𝐭 𝐰𝐨𝐫𝐤 𝐬𝐡𝐨𝐰𝐢𝐧𝐠 𝐡𝐨𝐰 𝐩𝐨𝐥𝐲𝐬𝐢𝐚𝐥𝐲𝐥𝐚𝐭𝐢𝐨𝐧, 𝐚 𝐫𝐚𝐫𝐞 𝐩𝐫𝐨𝐭𝐞𝐢𝐧 𝐦𝐨𝐝𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧, 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐞𝐬 𝐢𝐧𝐟𝐥𝐚𝐦𝐦𝐚𝐭𝐨𝐫𝐲 𝐦𝐨𝐧𝐨𝐜𝐲𝐭𝐞 𝐦𝐨𝐛𝐢𝐥𝐢𝐳𝐚𝐭𝐢𝐨𝐧 𝐟𝐫𝐨𝐦 𝐭𝐡𝐞 𝐛𝐨𝐧𝐞 𝐦𝐚𝐫𝐫𝐨𝐰.

✍️ Aurélien Boyancé, Nelly Gilles, @yoannrombouts.bsky.social & coll. @ipbstoulouse.bsky.social

📖 shorturl.at/IDwza

👇 A short thread...

13.01.2026 06:20 — 👍 18    🔁 10    💬 2    📌 1
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Albertus Viljoen Leads Indo-French Collaborative Research on Mycobacterial Biofilms - IPBS-Toulouse The Indo-French Centre for the Promotion of Advanced Research (IFCPAR/CEFIPRA) fosters cutting-edge scientific collaboration between[…]

𝐖𝐞 𝐚𝐫𝐞 𝐩𝐥𝐞𝐚𝐬𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐞𝐱𝐜𝐢𝐭𝐢𝐧𝐠 𝐧𝐞𝐰𝐬 𝐢𝐧 𝐈𝐧𝐝𝐨-𝐅𝐫𝐞𝐧𝐜𝐡 𝐬𝐜𝐢𝐞𝐧𝐭𝐢𝐟𝐢𝐜 𝐜𝐨𝐥𝐥𝐚𝐛𝐨𝐫𝐚𝐭𝐢𝐨𝐧 🇮🇳🇫🇷

With IFCPAR/CEFIPRA funding, Albertus Viljoen will co-coordinate a project with Prof. Madhavan K. Nampoothiri (CSIR-NIIST, India) on mycobacterial biofilms and antimicrobial resistance.

More details: shorturl.at/EI0VY

08.01.2026 17:24 — 👍 2    🔁 0    💬 0    📌 0
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🚨 We are excited to announce that @virginiestevenin.bsky.social has been awarded a starting grant from the @frm-officiel.bsky.social to establish her research team at IPBS and study the nutrition of pathogenic bacteria inside human host cells.
More info: shorturl.at/U6zSa

#MicroSky #Salmonella

18.12.2025 04:48 — 👍 18    🔁 4    💬 0    📌 1
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🚨 We are excited to announce that @virginiestevenin.bsky.social has been awarded a starting grant from the @frm-officiel.bsky.social to establish her research team at IPBS and study the nutrition of pathogenic bacteria inside human host cells.
More info: shorturl.at/U6zSa

#MicroSky #Salmonella

18.12.2025 04:48 — 👍 18    🔁 4    💬 0    📌 1
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🚨 𝐍𝐞𝐰 𝐩𝐫𝐞𝐩𝐫𝐢𝐧𝐭 𝐟𝐫𝐨𝐦 𝐨𝐮𝐫 𝐥𝐚𝐛, 𝐚𝐧𝐝 𝐚 𝐟𝐢𝐫𝐬𝐭 𝐢𝐧 𝐭𝐡𝐞 𝐓𝐁 𝐟𝐢𝐞𝐥𝐝! 🚨

We’re thrilled to share our new study revealing how the chromatin regulator SP140 preserves protective T cell immunity during #tuberculosis infection by restraining harmful type I IFN responses.

📖 𝗥𝗲𝗮𝗱 𝘁𝗵𝗲 𝗽𝗿𝗲𝗽𝗿𝗶𝗻𝘁: shorturl.at/r5jd9

11.12.2025 06:07 — 👍 22    🔁 9    💬 1    📌 0
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𝗜𝗣𝗕𝗦 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵𝗲𝗿𝘀 𝗶𝘀𝗼𝗹𝗮𝘁𝗲𝗱 𝗵𝘂𝗺𝗮𝗻 𝗿𝗲𝗴𝘂𝗹𝗮𝘁𝗼𝗿𝘆 𝗯𝗼𝗻𝗲 𝗺𝗮𝗿𝗿𝗼𝘄 𝗮𝗱𝗶𝗽𝗼𝗰𝘆𝘁𝗲𝘀 𝗳𝗼𝗿 𝘁𝗵𝗲 𝗳𝗶𝗿𝘀𝘁 𝘁𝗶𝗺𝗲!

These anucleate fat cells still metabolize lipids and glucose, support blood cell production, and may shape the bone marrow niche and hematopoiesis.🩸

📖 shorturl.at/bunUV
#Hematopoiesis #Adipocytes #BoneMarrow

05.12.2025 12:48 — 👍 3    🔁 2    💬 0    📌 0

Hey friends. I’m looking for a postdoc interested in studying host-pathogen interactions and immunology of tuberculosis. Send me some good people! We have a great group here! Email me joanne@pitt.edu. Thanks!

04.12.2025 17:12 — 👍 24    🔁 30    💬 1    📌 1
Intravital lung microscopy unveils T cell dynamics in mouse tuberculosis lesions Protective immunity to Mycobacterium tuberculosis (Mtb) depends on the ability of T cells to access and engage infected cells within lung lesions, yet these spatiotemporal interactions remain poorly d...

www.researchsquare.com/article/rs-8...

📖 Emma Lefrancais and coll.

#Microsky #Immunosky

03.12.2025 17:43 — 👍 1    🔁 0    💬 0    📌 0
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IPBS researchers created LiveLung-TB, a BSL-3 imaging platform that visualizes real-time immune responses in Mtb-infected lungs. They found most CD4 T cells fail to reach infected cells, revealing physical barriers that limit TB immunity—a new window into host-pathogen dynamics! 🔬🫁
#Tuberculosis

03.12.2025 17:43 — 👍 11    🔁 5    💬 2    📌 0
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Comment les filaments d'actine s'organisent à l'intérieur des cellules et des tissus vivants En utilisant la microscopie de fluorescence résolue en polarisation, les biologistes et physiciens de l'Institut Fresnel, associés à une équipe internat

#RésultatScientifique 🔎 | Comment les filaments d'actine s'organisent à l'intérieur des cellules et des tissus vivants

🔬 @institutfresnel.bsky.social 🤝 @univ-amu.fr @centralemed.bsky.social @cnrs.fr
📍 @cnrs-dr12.bsky.social

26.11.2025 09:57 — 👍 15    🔁 11    💬 1    📌 0
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We are thrilled to congratulate @lucianabalboa.bsky.social, co-leader of our IPBS/CNRS-CONICET lab, for receiving a special mention in the L’Oréal-UNESCO “For Women in Science” Award 2025. This honor recognizes her exceptional career & dedication to research in infectious diseases.
shorturl.at/Gfo4a

13.11.2025 06:46 — 👍 3    🔁 1    💬 0    📌 1
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A huge thank you to our PhD students, the organizing committee, and our guest speakers @mblokesch.bsky.social, F. Mechta-Grigoriou & E. Crubezy for making the 10th IPBS Student Symposium such a success.
Kudos to everyone involved!

On to the 11th Symposium! 🎉

05.11.2025 14:07 — 👍 5    🔁 2    💬 1    📌 0
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Un immense merci à nos doctorants, au comité organisateur et à nos orateurs invités @mblokesch.bsky.social, F. Mechta-Grigoriou & E. Crubezy, pour la réussite de ce superbe 10e Symposium des étudiants de l’IPBS.
Bravo à toutes et à tous !

Cap sur le 11e Symposium !

05.11.2025 14:06 — 👍 9    🔁 2    💬 0    📌 0

Exciting #postdoc opportunity in KL Ung's group!
Understanding the molecular mechanisms of cell wall remodeling in pathogens

Learn more: shorturl.at/gPuFV
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Protein #Biochemistry #StructuralBiology #Biophysics #CryoEM

04.11.2025 05:34 — 👍 6    🔁 10    💬 0    📌 0
Early-life Immune Imprinting and Inflammatory Diseases - IPBS-Toulouse Our team studies neonatal immunity. We are particularly interested in mapping the mucosal cell subsets[…]

Exciting #postdoc opportunity in T. Gensollen's group!
How early-life interactions between the immune system and microbiota shape lifelong immune imprinting and disease risk
Learn more: shorturl.at/F8hqE
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Immunology #Microbiology #Microbiota #Omics

04.11.2025 05:32 — 👍 4    🔁 4    💬 0    📌 0
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La protéine Moésine régule le remodelage osseux en modulant la fusion et l’activité des ostéoclastes - IPBS-Toulouse Des chercheurs de l’Institut de Pharmacologie et Biologie Structurale (IPBS) ont mis en évidence un[…]

Des chercheurs de l’IPBS (@chrisverollet.bsky.social et coll.) ont découvert que la protéine moésine régule les ostéoclastes, les cellules qui résorbent l’os. Sans elle, les os s’affaiblissent. Une piste prometteuse contre l’ #ostéoporose.

📘 @jcb.org shorturl.at/OhNSa

27.10.2025 17:29 — 👍 4    🔁 3    💬 0    📌 1
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Moesin Protein Controls Bone Remodeling by Regulating Osteoclast Fusion and Function - IPBS-Toulouse Researchers at the Institut de Pharmacologie et Biologie Structurale (IPBS) have uncovered a pivotal role[…]

Too much cell fusion can break your bones, literally!
IPBS researchers @chrisverollet.bsky.social & coll. found that moesin keeps bone-resorbing cells (osteoclasts) in check.
Without it, bones weaken, a discovery that could inspire new #osteoporosis treatments.

📘 @jcb.org shorturl.at/N0Esc

27.10.2025 17:17 — 👍 5    🔁 3    💬 0    📌 0
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phd-pub.ipbs.fr La saison 2025-2026 du PhD-Pub Toulouse ouvre ses portes !Vous êtes doctorant à Toulouse, toutes disciplines confondues, et souhaitez partager vos recherches avec le grand public dans une ambiance conviviale ?

Vous êtes doctorant-e-s à Toulouse, toutes disciplines confondues, et souhaitez partager vos recherches avec le grand public dans une ambiance conviviale ?
Rejoignez le PhD-Pub Toulouse !
📍 Lieu : Pub l’Autruche,Toulouse
📢 Les inscriptions pour la saison 2026 sont ouvertes
-> phd-pub.ipbs.fr

14.10.2025 11:33 — 👍 1    🔁 0    💬 0    📌 0
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Le PhD-Pub Toulouse, c'est 4 présentations de 10 minutes, accessibles et interactives, des échanges libres entre le public et les doctorants, alors rejoignez nous pour échanger et s'amuser en parlant science le 21 octobre.
Tous les informations et les portraits des doctorants : phd-pub.ipbs.fr

14.10.2025 09:26 — 👍 1    🔁 0    💬 0    📌 0
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Pink October campain: In 2025, IPBS researchers advance the fight against breast cancer with innovative therapies and patient-focused treatments. Together, we progress science and hope for a cancer-free world.
www.ipbs.fr/a-year-of-ca...

#PinkOctober #BreastCancer #IPBS #Research #Hope

13.10.2025 08:55 — 👍 1    🔁 0    💬 0    📌 0
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Un point faible du bacille de la tuberculose identifié Dans une étude parue dans PNAS, des scientifiques dévoilent que la survie d

#ResultatScientifique🔎| Un transporteur spécifique du bacille de la tuberculose pourrait être la cible de médicaments ?

✍️ @oneyrolles.bsky.social
🤝 @ipbstoulouse.bsky.social
📕 @pnas.org | buff.ly/XAynagm

23.09.2025 14:00 — 👍 5    🔁 4    💬 0    📌 0
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Inorganic sulfate is critical for Mycobacterium tuberculosis lung tissue colonization and redox balance | PNAS Tuberculosis remains the deadliest infectious disease caused by a single pathogen, highlighting the urgent need for novel therapies. A deeper under...

Excited to share Wendy Le Mouëllic’s PhD work, now published in @pnas.org!
It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance.
Huge congrats to Wendy & colleagues!
shorturl.at/WbFQC

23.09.2025 03:32 — 👍 64    🔁 31    💬 3    📌 1
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Another memorable #TBVACHORIZON WP1 working group meeting in Basel, Switzerland! Grateful to #TBVI and many thanks to Daniel Pinschewer and colleagues for the warm welcome and inspiring discussions.
@unibas.ch @horizoneu.bsky.social

19.09.2025 11:45 — 👍 4    🔁 1    💬 0    📌 1

We are looking to hire post-docs to work on T cell responses to M. tuberculosis infection using murine and NHP models. If you know T cells and wanna work on the top global infectious killer check us out. BSL3 experience not required. The NIH intramural program in Bethesda MD is an amazing place!

17.09.2025 17:50 — 👍 19    🔁 15    💬 0    📌 2
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Prof. Raju Mukherjee visits IPBS as SSHN laureate - IPBS-Toulouse IPBS welcomes Prof Raju Mukherjee, visiting professor and laureate of the SSHN program of the[…]

Very please to welcome visiting Prof. Raju Mukherjee, SSHN laureate!
@ifiofficiel.bsky.social

www.ipbs.fr/prof-raju-mu...

25.08.2025 16:04 — 👍 1    🔁 0    💬 0    📌 0
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From tuberculosis to rheumatoid arthritis: A glycobiology breakthrough enters the valorization phase
👏 @yoannrombouts.bsky.social
Thanks @frm-officiel.bsky.social
More info: shorturl.at/i3sQd

29.07.2025 09:39 — 👍 3    🔁 1    💬 0    📌 0

@chrisverollet.bsky.social @etienne-meunier.bsky.social

18.07.2025 05:33 — 👍 0    🔁 0    💬 0    📌 0
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Big news from IPBS! Our researchers are coordinators or partners in 8 cutting-edge projects funded by @agencerecherche.bsky.social

From DNA vaccine electroporation to drug-resistant pathogens, bone health, allergy, and proteasomes, IPBS is driving innovation in biomedicine!
urls.fr/gt6JZf

18.07.2025 05:29 — 👍 5    🔁 1    💬 2    📌 0

@ipbstoulouse is following 20 prominent accounts