Megan Harwig 🔬

Know anyone looking for a microscopy sales position? Check out this job at Oxford Instruments plc: www.linkedin.com/jobs/view/43... 🔬

BigVolumeBrowser: a new 3D multi volume/mesh/point clould (SMLM) data viewer Hello everyone, I’d like to share with you another 3D viewer for FIJI, BigVolumeBrowser (full documentation link). It‘s a first initial public release, so there is still space for improvements. Le...

Finally, the first public release of #BigVolumeBrowser, so after teasers, you can try it yourself. For details, please check the announcement post (1/2)
forum.image.sc/t/bigvolumeb...

We are hiring an Imaging Scientis. Apply here: go.mbl.edu/AS1887

We are looking for perfusion/microfluidics systems that are compatible with OKO chambers on our Dragonfly spinning disk confocal microscopes in our core. Does anyone have any recommendations of products you love that do not leak? 🔬🧪🧬🥼

Glia Responses after Injury with Laser Ablation in Zebrafish- Oxford Instruments Discover how the Kucenas Lab uses our confocal microscopes and precise laser ablation to study glial development, injury response, and dynamics in Zebrafish.

Soon our core will be getting a MicroPoint4 tool for our Dragonfly 620SR. Anyone else have a MicroPoint tool? What has been your favorite application?

andor.oxinst.com/learning/vie...

Research Scientist I Medical College of Wisconsin - Research Scientist I - Milwaukee WI 53201

Come work with us at MCW! This position is in the Translational Metabolomics-Preclinical Imaging Shared Resource. This position involves imaging mice, rats and other small animal models with multimodal imaging.

careers.peopleclick.com/careerscp/cl...

It has been a dream come true to lead a rotation in the @mblscience.bsky.social Physiology course - thanks to the amazing Directors @gladfelterlab.bsky.social and @brangwynnelab.bsky.social, course staff, TAs, and students!

A logo showing a stylised computer monitor, with a cube in the style of a volume electron microscopy dataset. The text below reads "CCP-volumeEM - Collaborative Computational Project for Volume Electron Microscopy"

If you work in #VolumeEM, please fill in our survey to help us build a Collaborative Computational Project for volumeEM!

Survey link: forms.office.com/e/eMAJGCKUnc

we're aiming to identify the needs of the community in order to build a roadmap for all-things data-related in #vEM

The recording of our recent webinar, "Next-generation expansion microscopy: 20× magnification in one step" by @shiweiw.bsky.social, is now available! You can access it at: bio-protocol.org/webinar/deta...

#Webinar #LifeSciences

Our groundbreaking Dark Sectioning technique is now published in Nature Methods! 🎉 It supercharges existing imaging systems:
🔬 Widefield → Confocal
🔬 Single-photon → Multiphoton
🔬 2D-SIM → 3D-SIM
Now integrated in Airy PolarSIM and #FlexSIM!
doi.org/10.1038/s415...
#Microscopy #Fluorescence

Revolutionizing High-Speed Dynamic Fluorescence Imaging with Deep Learning-Enhanced Denoising Techniques Researchers have unveiled a groundbreaking advancement in the field of fluorescence microscopy, designed to resolve one of the most significant challenges facing scientists: image degradation due to noise in dynamic in vivo imaging. This innovative method, recently published in the journal PhotoniX, presents a self-supervised deep learning approach known as Temporal-gradient empowered Denoising (TeD). The newly developed technique stands to revolutionize the way researchers capture and analyze high-speed biological processes, which are often severely obscured by noise.

Revolutionizing High-Speed Dynamic Fluorescence Imaging with Deep Learning-Enhanced Denoising Techniques

Researchers have unveiled a groundbreaking advancement in the field of fluorescence microscopy, designed to resolve one of the most significant challenges facing scientists: image degradation…

BioTechniques Image Competition 2025 Submit your scientific images to the BioTechniques Scientific Image Competition 2025! Enter now for the chance to win a US$200 gift card.

⭐ The 2025 BioTechniques Image Competition is now open! 🔬

You have until 17 June to submit up to ten scientific images or illustrations that you’ve taken or created during your research.

Prizes, rules and how to enter >>> www.biotechniques.com/life-science... 🧪

#imaging #microscopy

Practical guidelines for cell segmentation models under optical aberrations in microscopy. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.09.002

🤖 How resilient are deep learning models to real-world imperfections in microscopy?

🔗 Practical guidelines for cell segmentation models under optical aberrations in microscopy, DOI: doi.org/10.1016/j.cs...

📚 CSBJ Quantum Biology and Biophotonics: www.csbj.org/qbio

#CellSegmentation #Microscopy

Today is the deadline to apply! Come hang out with our team in Boston and learn to think about bioimage analysis and how to use many fun open source tools!

Did you know that Bioimage Archive has a specific database for people to share AI-ready imaging datasets? I did not until @yanlanmao.bsky.social told me! Please deposit! If people regularly submitted, it would have a huge collective impact on bioimage analysis. www.ebi.ac.uk/bioimage-arc...

Efficient, standards-based #bioimaging data management is essential for research and reuse. Join the presentation about “A Journey to #FAIR Bioimage Data,” a contribution to
@ebi.embl.org's STANDFLOW project webinar series.

🗓️ July 2, 2025 | 02:30–03:30 pm

👉 Register: www.ebi.ac.uk/training/eve...

📄 A recent review article covers the latest in next-generation #Fluorophores and site-specific labeling strategies for different types of biomolecules, including info on their application in areas such as #SuperResolution #Microscopy: bit.ly/3Fhbeh9

#Fluorescence

A suite of bridged rhodamine dyes for fluorescence microscopy, named BriDyes, offers excellent brightness, photostability, solubility, cell permeability, and resistance to photoblueing.

www.nature.com/articles/s41...

Image-processing methods for electron microscopy of biological specimens The focused issue on Image-processing methods for electron microscopy of biological specimens is introduced. The virtual issue is available at https://journals.iucr.org/special_issues/2025/imageprocessing.

Carlos Oscar S. Sorzano et al.: Image-processing methods for electron microscopy of biological specimens ... #IUCr https://journals.iucr.org/paper?S2059798325004449

By democratizing bioimage analysis, BiaPy is paving the way for faster, more inclusive scientific breakthroughs, bringing us closer to understanding the building blocks of life.

https://mappingignorance.org/2025/05/15/biapy-analising-bioimages-made-easy/

Seeing Is Believing: The Microscopes Powering Modern Life Sciences As someone who works closely with life science researchers and imaging technologies, I often get a surprisingly common question: "You sell microscopes? Like for high school labs? Or on Amazon? Or for ...

Ever wonder which microscopes power today’s life science breakthroughs? 🧬🔬 I put together a quick guide—from brightfield to holography.
Check it out 👉 www.linkedin.com/pulse/seeing...

#Microscopy #LifeSciences #Biotech #SpatialBiology #ImagingScience #SciComm

MicroscoPills: your bite-sized dose of microscopy concepts Podcast · Dr Alessandro Esposito · Unlock the tiny world with short episodes on microscopy and its application to biology and biomedical research. Discover how these tools visualise life at the molecu...

Good morning! Today we publish three new #MicroscoPills about #confocal #microscopy.

E03 - What is it and why is it useful in #biology
E04 - Confocal microscopy history and evolution
E05 - The role of the confocal #pinhole

Follow us on Spotify

open.spotify.com/show/20hJTM4...

#science

Light-microscopy-based connectomic reconstruction of mammalian brain tissue - Nature A technique called LICONN (light-microscopy-based connectomics) allows mapping of brain tissue at synapse level and simultaneous measurement of molecular information, thus enabling quantification of c...

Thanks to expansion microscopy, clever labeling, and modern segmentation approaches, doing connectomics with #light #microscopy has become feasible - huge congratulations Mojtaba & the Danzl lab at @istaresearch.bsky.social !
www.nature.com/articles/s41...

FREE Help with Bioimage Analysis!

Light sheet microscopy Light sheet microscopy is a technology that enables near-isotropic imaging of large biological specimens over time. It opens new avenues to study biological processes with unprecedented imaging speed…

Deadline extended to 19 May! 🧪 Learn about light sheet #microscopy, sample preparation, data processing and #ImageAnalysis. Apply now for EMBO Practical Course on Light sheet microscopy in Dresden, Germany, 11–22 August

meetings.embo.org/event/25-lsm
#EMBOlsm #imaging #EMBOevents

You can now apply until the 4th of June !!
#EMBOBioImage www.embl.org/about/info/c...

Ad for the Bioimage Analysis Beginnings Bootcamp at the Broad Institute. Where & When Broad Institute, 415 Main Street, Cambridge MA (in-person only) Monday–Friday, August 4–8, 20259:00 AM – 5:00 PM About the Bootcamp Learn core bioimage analysis skills using open-source tools for light microscopy in this hands-on, in-person course. The Bootcamp covers annotation, segmentation, and deep learning fundamentals. Fee: $600 (Academic/Non-Profit) | $1000 (Industry/For-Profit) For more information email ImagingAdmin@broadinstitute.org

BIG NEWS - for the first time ever, we're running a Bioimage Analysis Beginnings Bootcamp. Learn #bioimageanalysis from awesome folks, and gain familiarity with some new tools as well as how to pick the right tool in the first place. Aug 4th-8th - apply here (soon!) forms.gle/d2fCXsrWHVP8...

Trump's NIH director takes questions at Medical College of Wisconsin amid broad research cuts President Trump's new NIH director took questions from Medical College of Wisconsin researchers, including one whose research grant had been canceled.

"I’ve heard a lot of panic in the community as if the support that the federal government has for science has ended and that science is no longer the priority. One of the reasons I was delighted to be able to come here was to assure people that is not true" #NIH
www.jsonline.com/story/news/p...

On April 19, 1898, Camillo Golgi described what we now know as the #Golgi apparatus - a structure so pretty and unusual it took over fifty years for the scientific community to agree it wasn’t just an artefact.
April 19 is #GolgiDay! Mark your calendars to honour the best organelle.

Where do proteins go in cells? Next-generation methods map the molecules’ hidden lives Nature - Spatial proteomics is helping biologists to uncover how cells work by mapping where proteins operate.

If you want to understand how cells function, you have to work out what proteins interact with — and where

https://go.nature.com/3RgNXOZ